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24 Cards in this Set

  • Front
  • Back
c-myc
oncogene *t(8:14)*, burkitt's lymphoma
bcl-2
oncogene (t(14:18)), follicular and undiff lymphomas
erb-B2
oncogene, breast, ovarian, gastric Carcinoma
ras
oncogene, colon ca
L-myc
oncogene, lung tumor
N-myc
oncogene, neuroblastoma
ret
oncogene, MEN(II and III)
Rb
tumor suppressor gene, (13q) retinoblastoma, osteosarcoma
BRCA1 and 2
tumor suppressor gene, (17q, 13q), breast and ovarian ca
p53
tumor suppressor gene, (17p-the only p) most human cancers, Li-fraumeni syndrome
APC
tumor suppressor gene, (5q) colorectal ca
WT1
tumor suppressor gene, (11q) Wilms' tumor (kidney embryo stuff)
NF1
tumor suppressor gene, (17) neurofibromatosis 1 (von recklinghaussen) cafe au lait, lisch in iris
NF2
tumor suppressor gene, (22q) neurofibromatosis 2 (bilat acoustic neuromas
DPC
tumor suppressor gene, (18q) pancreatic ca
DCC
tumor suppressor gene, (18q) colon cancer
CEA
tumor marker, colorectal/pancreatic ca (also made by gastric/breast ca)
alpha-fetoprotein
tumor marker, hepatocellular canonseminomatous germ cell toumors of testis
beta-hCG
tumor marker, Hydatidiform moles, Choriocarcinoma, Gestational trophoblastic tumors
CA-124
tumor marker, ovarian, malignant epithelial tumors
S-100
tumor marker, melanoma, neural tumors, astrocytomas
bombesin
neuroblastoma, (lung and gastric ca)
TRAP
hairy cell leukemia
alk phos
mets to bone, obstructed billiary disease, paget's