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27 Cards in this Set
- Front
- Back
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Nadir
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Lowest value of the cell count before recovery. Typically 7-10 days.
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Indications for neutropenic precautions
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<1500 WBC count
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Chemotherapy Side Effects
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*Myelosupression, mucositis, N, V, Diarrhea
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Chemotherapy Toxicities
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*Hemorrhagic Cystitis, Neurotoxicity, Hepatotoxicity, Nephrotoxicity, Cardiotoxicity, pulmonary fibrosis
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Cytoxan: SE
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*Hemmorhagic Cystitis, *Dermatitis, *Teratogenesis(danger to fetus)
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Cytoxan: NI
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FLUSH IT, void frequently, administrate MESNA before admin of Cytoxan,
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Cytoxan treats what types of cancers?
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Breast, ovary, testicular, and bladder....think secondary sex characteristics!
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Adriamycin: SE
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*100% alopecia, *cardiotoxicity, *Red/Orange urine and other body fluids, stomatitis, photosensitivity
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Adriamycin: dosage considerations
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500 mg/m2 LIFETIME DOSE
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Fluoracil: 5-FU, Xeloda
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Xeloda is only FDA approved for metastatic cancer
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Fluouracil: SE
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*hyperpigmentation of the vein and hyperpigmentation with sun exposure
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Fluouracil: Indications
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almost all cancers
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Adriamycin: Indications
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breast, ovarian, bladder, lung cancer, and Hodgkin's lymphoma
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Taxotere: Indications
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breast, non-small cell lung cancer, stomach cancer, head and neck cancer, and metastatic prostate cancer
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Taxotere: SE
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hypersensitivity reactions, fluid retention, neurotoxicity, and skin/nail changes
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Taxotere: NI
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premedicate with Decadron
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Oncovin: indications
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almost all. Note Wilms' tumor, Kaposi's sarcoma, *neuroblastoma
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Oncovin: NI
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never exceeed 2mg IVPB
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Oncovin: SE
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neurotoxicity, peripheral neuropathy, alopecia, constipations, paralytic ileus,jaw pain and foot drop
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Biotherapy
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enhances immune response
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Avastin
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monitor BP, give SLOW
Aids immune system |
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Neupogen
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Causes bone pain, decreased platelet count, and changes in liver function
Causes body to produce WBC Decreases incidence of infection |
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Epoetin alfa: what and initiate when?
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increases RBC production for anemia
initiate with Hgb is < 12.9% stop if HCT > 40% |
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Transplant Drugs
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Cyclosporin, CellCept, Immuran
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Cyclosporin
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Solid organ transplants
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CellCept
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Give on empty stomach
For Renal or heart transplant |
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Immuran
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teratogentic, hepatotoxic
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