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59 Cards in this Set
- Front
- Back
- 3rd side (hint)
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mechlorethamine
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Estramustine
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Melphalen
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Chlorambucil
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Cyclophosphamide
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Ifosfamide
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Bendamustine
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b-haloalkylamine Antineoplastic
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alkylates guanine at N-7
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Thiotepa
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Thio-organophosphate Antineoplastic
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alkylates guanine at N-7
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Carmustine
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Nitrosourea
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alkylates guanine at N-7
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Lomustine
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Nitrosourea
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alkylates guanine at N-7
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Streptozosin
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Nitrosourea Antineoplastic
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Alkylates Guanine at N-7
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Dacarbazine
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Triazene Antineoplastic
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Alkylates Guanine at O-6
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Temozolomide
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Triazene Antineoplastic
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Alkylates Guagine at O-6
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Procarbazine
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Hydrazine Antineoplastic
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Alkylates Guanine at O-6
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Busulfan
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Alkyl sulfonate
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Alkylates Guanine at N-7
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Altretamine
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Triazene Triamine Antineoplastic
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Alkylates Guanine at N-7
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Cisplatin
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Organoplatinum Antineoplastic
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Alkylates Guanine at N-7
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Carboplatin
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Organoplatinum Antineoplastic
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Alkylates Guanine at N-7
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Oxaliplatin
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Organoplatinum Antineoplastic
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Alkylates Guanine at N-7
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Azacitidine
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Cytidine analogue antineoplastic
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Inhibitor of DNA methyltransferase
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Decitabine
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Cytidine analogue
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Inhibitor of DNA methyltransferase
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Methotrexate
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Folic acid analogue antineoplastic
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Inhibits dihydrofolic reductase
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leukovorin
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folic acid prodrug/ antidote for DHFR inhibitor overdose
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Increase conc of tetrahydrofolic acid
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Flurouracil
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Uracil analogue/ antineoplastic
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Inhibits thymidylate synthetase
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Floxuridine
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Uracil analogue/ antineoplastic
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Inhibits thymidylate synthetase
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Capecitabine
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Uracil analogue/ antineoplastic
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Inhibits thymidylate synthetase
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6-mercaptopurine
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inosine analogue antineoplastic
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inhibits amidophosphoribosyl transferase
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6- thioguanine
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guanine analogue
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inhibits amidophosphoribosyl transferase
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Cytarabine
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Cytidine analogue Antineoplastic
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inhibits cytidine biosynthesis
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Gemcytidine
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Cytidine analogue Antineoplastic
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Inhibits RNA/DNA synthesis
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Fludarabine phosphate
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Guanine analogue Antineoplastic
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Inhibits RNA/DNA synthesis
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Cladribine
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Guanine analogue Antineoplastic
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Inhibits RNA/DNa synthesis
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Clorfarabine
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Guanine analogue Antineoplastic
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Inhibits RNA/DNA synehsis & inhibits ribonucleotide reductase
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Pentostatin
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Purine analogue
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Inhibits ribonucleotide reductase
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Hydroxyurea
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Hydroxyurea Antineoplastic
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Inhibits ribonucleotide reductase
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Doxorubicin
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Anthracycline Antibiotic Antineoplastic
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Intercalates in DNA and inhibits Topo II
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Daunorubicin
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Anthracycline Antibiotic Antineoplastic
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Intercalates in DNA and inhibits Topo II
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Idarubicin
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Anthracycline Antibiotic Antineoplastic
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Intercalates in DNA and inhibits Topo II
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Epirubicin
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anthracycline antibiotic antineoplastic
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Intercalates in DNA and inhibits Topo II
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Valrubicin
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anthracycline antibiotic antineoplastic
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Intercalates in DNA and inhibits Topo II
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Mitoxantrone
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Anthracenedione antibiotic antineoplastic
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Intercalates in DNA and inhibits Topo II
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Dactinomycin
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Polypeptide antibiotic antineoplastic
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Intercalates in DNA and inhibits Topo II
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Mitomycin
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Aziridine antibiotic antineoplastic
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alkylation of guanine @N-2 or cytosine @N-4
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Bleomycin
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Peptide antibiotic antineoplastic
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Induces single stranded breaks in DNA
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Vinorelbine
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Vinca alkaloid, mitotic inhibit antineoplastic
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Inhibits tubulin polymerization
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Vincristine
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Vinca alkaloid, mitotic inhibit antineoplastic
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Inhibits tubulin polymerization
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Vinblastine
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Vinca alkaloid, mitotic inhibit antineoplastic
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Inhibits tubulin polymerization
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Paclitaxel
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Taxane, mitotic inhibit antineoplastic
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inhibits microtubulin depolymerization
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Docetaxel
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taxane, Mitotic inhibitor antineoplastic
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Inhibits microtubulin depolymerization
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Ixabepilone
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Epothilone B lactam analogue, mitotic inhibitor antineoplastic
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Inhibits microtubulin depolymerization
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Etoposide
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Epipodophyllotoxin, Mitotic inhibitor antineoplastic
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InhibitsTopo II
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Teniposide
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Epipodophyllotoxin, Mitotic inhibitor antineoplastic
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inhibits topo II
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Camptothecin
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Quinoline alkaloid, mitotic inhibitor antineoplastic
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Inhibits topo I
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Topotecan
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Quinoline alkaloid, mitotic inhibitor antineoplastic
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Inhibits topo I
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Irinotecan
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Quinoline alkaloid, mitotic inhibitor antineoplastic
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Inhibits topo I
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Pegasparagase
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Pegylated Asparginase, antineoplastic
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Inhibits production of L-aspargine
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imatinib
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Phenylaminopyrimidine, Antineoplastic
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Inhibits tyrosine Kinase -PDGF-R and BCR-ABL
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Sunitimab
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Fluoroindole der. Antineoplastic
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Inhibits tyrosine kinae - PDGF-R and VEGF-R
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Dasatinib
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Piperazine thiazole der. Antineoplastic
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Inhibits tyrosine kinase - BCR ABL
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