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16 Cards in this Set
- Front
- Back
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Blocks transcription of cyclins E & A
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Retinoblastoma
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Blocks CDK 2 & 4
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p21
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Induces transcription of p21
Promotes Apoptosis |
p53
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Blocks cyclin D - CDK 4
& cyclin E - CDK 2 |
p27
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-Blocks formation of Microtubules
-interferes formation of mitotic spindle |
Vincristine
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-Hydrolyzes asparagine to aspartic acid
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Asparginase
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-Adrenal corticosteroid
-Anti-inflammatory |
Dexamethasone
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inhibits metabolism of folic acid
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Methatrexate
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intercalates w/ DNA
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Doxorubicin
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inhibits purine synthesis
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Mercaptopurine
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Alkylates & cross links DNA
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Cyclophosphamide
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Pyrimidine analogue for cytosine
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Cytosine arabinoside
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Inhibits Eukaryotic Topoisomerase
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Etoposide
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Disrupts F actin
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Cytochalasin
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Stabilizes F actin
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Phalloidin
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Stabilizes Microtubule Cytoskeleton
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Taxol
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