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7 Cards in this Set
- Front
- Back
what 3 things regulate epiphyseal plate activity?
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IGF-1, insulin, T3
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what things regulate continuous remodeling?
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PTH and cytokines stimulate osteoclasts
sex steroids and calcitonin inhibit osteoclasts |
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eight steps in epiphyseal plate activity
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chondrocyte --> cartilage synthesis --> calcification --> erosion --> osteoblast invasion --> osteoid --> mineralization
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what is osteomalacia?
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long standing depletion of vitamin D.
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5 roles of calcium
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1) neurotransmitter release
2) excitation-concentration coupling 3) sgnal transduction 4) enzyme cofactor 5) bone-hydroxyapatite |
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4 roles of phosphorus
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1) buffer
2) nucleic acids 3) regulatory phoshorylations 4) bone-hydroxyapatite |
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3 hormones that regulate blood calcium and phosphorus
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1) PTH
2) calcitonin 3) 1,25 (OH)2 Vitamin D3 |