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10 Cards in this Set

  • Front
  • Back

Coordinated by these organs

Bone


Kidney


Intestine

Controlled by these hormones

Parathyroid


Calcitonin


1,25-dihydroxycholecalciferol (Active form of vitamin D) (kidney converts this)

Stimulator of parathyroid hormone

Low levels of Ca2+ at

Effect of PTH

CAlcium resortption from bone


Promotes Ca2+ resorption in the thick ascending limb and distal convoluted tubule


Hydroxylate 25-OH vit D into 1,25 OH vit D


Inhibits phosphate reabsorption in the proximal and distal tubule


At intestine, promotes Ca2+ reabsorption secondary to production of active vitamin D made by PTH in the kidneys

Why we don't want both phosphate and calcium high at the same time

Formation of crystals (calcium phosphate salt)


Ultimately decreases blood calcium level

Calcitonin production site

Thyroid gland

Calcitonin trigger

Ca2+ above normal

Calcitonin effects

Reduce bone resorption by reducing osteoclast action

Sex hormones that maintain bone

Testosterone


Estradiol (reduction of this after menopause associated with osteoporosis)

Glucocorticoid excess leads to

Osteoporosis


Inhibits osteoblasts


Inhibits gastrointestinal calcium absorption