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55 Cards in this Set

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Natural Penicillins are DOC for?
Streptococcal infx
Syphillis
Dental infx
What are the anti-staphylococcal penicillins?
Nafcillin
Oxacillin
Dicloxacillin
Cloxacillin
Methicillin
Anti-staphylococcal penicillins are DOC for?
Staph aureus
Aminopenicillins are DOC for?
Enterococcus (w/AMG)
Listeria
Acute otitis media
Acute bacterial sinusitis
Bronchitis
Prophylaxis against endocarditis
Mezlocillin and piperacillin had action against what?
Pseudomonas
Augmentin is used for?
Beta-lactamase producing strains of staph
B. fragilis
Timentin and Zosyn are used for?
Pseudomonas
All cephalosporins are inactive against?
Listeria
Entercoccus
Which 4 cephs have MTT side chain?
Cefamandole
Cefoperazone
Cefotetan
Cefmetazole
1st generation cephs?
Cefazolin, cephalothin, cephapirin, cephalexin, cefadroxil, cephradine
1st gen cephs are DOC for?
Skin infx (cellulitis, impetigo)
Surgical prophylaxis
2nd gen cephs?
Cefamandole, cefmetazole, cefoxitin, cefuroxime, cefotetan, cefonicid, cefaclor, cefprozil, loracarbef
Most potent cephs against anaerobes?
Cefmetazole, cefoxitin, cefotetan
Ceph w/ good biliary penetration?
Cefamandole
Oral cephs are good for?
Otitis media
Sinusitis
2nd gen ceph that causes serum sickness?
Cefaclor
3rd gen cephs?
Cefotaxime, ceftazidime, cefdinir, ceftriaxone, cefixime
3rd gen cephs have NO coverage of this?
Anaerobes
3rd gen ceph with good pseudomonas coverage?
Ceftazidime
DOC for Neisseria meningitidis?
Ceftriaxone
Which 3rd gen ceph should be separated from Al, Mg, & Fe?
Cefdinir
4th gen ceph?
Cefepime
Good for what coverage?
Pseudomonas
Noscomial infx
Carbapenem agents?
Imipenem/Cilastatin
Meropenem
Carbapenem ADR?
Seizures
Use for carbapenems?
Empiric tx for mixed infx or severe noscomial infx
Ertapenem lacks coverage of these?
pseudomonas
enterococcos
acinetobacter
Ertapenem dosing?
once-a-day
Monobactam agent?
Aztreonam
Monobactam coverage?
gram negative only
Erythromycin is DOC for?
mycoplasma pneumo.
legionella
diptheria
pertussis
chlamydia trach.
Conditions treated by azith. and clarith.?
acute RTI
pharyngitis
tonsillitis
otitis media
skin and soft tissue infx
CAP
Conditions treated by ketolide?
exacerbations in COPD
acute sinusitits
CAP
CI for ketolide?
not with macrolide tx
ADR of clindamycin?
C. diff colitis
ADRs of chloramphenicol?
anemia, bone marrow suppression, gray baby sx
What causes Fanconi sx?
expired tetracyclines
Conditions treated by TTCNs?
chronic bronchitis exac.
UTIs
syphillis in PCN-allergic
Brucellosis
Lyme dx
Chlamydia
Rickettsia
What decreases TTCN absorption?
dairy products, Al, Ca, Mg, Fe
ADRs of TTCN?
teeth discoloration, photosensitivity
Uses for Tigecycline?
in pts >18 yo for skin infx including MRSA, intra-abdominal infx including B. fragilis but not pseudomonas
MOA of Bactrim?
PABA antagonist, inhibits folic acid synthesis, bacteriostatic
Bactrim is DOC for?
UTI
PCP
MOA of quinolones?
inhibit DNA gyrase and topo IV, bactericidal
Conditions treated by quinolones?
Lower RTI
UTIs
pneumonia
GI infx
CI of quinolones?
Pts <18yo
2nd gen quinolones best against?
gram negatives
3rd gen quinolones better against?
Strep. pneumo.
Metronidazole does not cover these?
aerobes
DI w/ metronidazole?
warfarin
Use for linezolid?
resistant gram + including VRE
DI with linezolid?
serotonergic agents and tyramine foods
Use for quinapristin/dalfopristin?
resistant gram +
MOA for daptomycin?
disruption of bacterial membrane fx
Use for daptomycin?
skin infx due to gram +