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28 Cards in this Set
- Front
- Back
Lymphatic and Immune Systems (4 functions)
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1. Maintains fluid balance
2. Protects body from infections and disease 3. Lipid absorption 4. Fluid Recovery |
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Describe Lymph.
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Clear, colorless fluid
Similar to plasma but with less protein |
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What occurs during fluid recovery of the lymphatic system?
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Absorbs plasma proteins and fluid
2-4 L/day from tissues and returns to bloodstream |
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Lymphatic Vessels layers
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1. Tunica interna [endothelium and valves]
2. Tunica Media [elastic fibers, smooth muscle] 3. Tunica Externa [thin outer layer, facilitates drainage] |
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Lymph Flow
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Vessels course through lymph node
Lymphatic trunks drain body into collecting ducts |
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Right Lymphatic Duct
(receives lymph from ?) |
From R. Arm
R. side of head and thorax Empties into R. Subclavian vein |
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Thoracic Duct
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Lymph from below diaphragm, Left Arm.
Left side of Head, Neck and Thorax empties into Left Subclavian vein. |
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Right Lymphatic duct empties into?
Thoracic duct empties into ? |
Right -> Right subclavian vein.
Thoracic --> left subclavian vein |
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What about the lymphatic system is an important diagnostic piece?
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lymphatic drainage
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Lymphatic Cells (List)
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1. Natural Killer Cells (NK) cells
2. T lymphocytes (T cells) 3. B lymphocytes (B cells) 4. Macrophages (APC) 5. Dendritic cells (APC) 6. Reticular cells (APC) |
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Which lymphatic cells are APCs (Antigen-presenting cells) ?
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Macrophages
Dendritic cells Reticular cells |
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NK Cells are responsible for ?
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Immune surveillance
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T lymphocytes mature where?
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in thymus
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B lymphocytes
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Activation causes proliferation and differentiation into plasma cells that produce antibodies
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Antigen-presenting cells do what?
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Process foreign matter and display antigenic fragments of it to certain T cells, alerting the immune system to the presence of an enemy.
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Macrophages are?
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Very large, avidly phagocytotic cells of connective tissues; from monocytes; phagocytize tissue debris, dead neutrophils, bacteria, and other foreign matter
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Dendritic cells are ?
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Branched, mobile APCs found in epidermis, mucous membranes, and lymphatic organs.
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Reticular cells are in?
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Stroma of lymph organs
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Lymphatic tissue
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Aggregation of lymphocytes in the connective tissues of mucus membranes and different organs.
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Different forms of lymphatic tissue
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1. Mucosa-associated lymphatic tissue (body passages open to exterior)
2. Lymphatic nodules (dense masses) 3. Peyer patches (ileocecal jcxn) |
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Primary Lymphatic Organs (2)
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Red Bone Marrow + Thymus
- B and T lymphocytes become immunocompetent = recognize and respond to antigens |
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Secondary Lymphatic Organs (3)
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Lymph nodes, tonsils, spleen
- have immunocompetent lymphocytes only after the cells mature in primary lymphatic organs |
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Most famous lymph node?
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Tonsils
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3 Sets of Tonsils
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1. 2 Palatine tonsils (oral cavity)
2. 2 Lingual tonsils 3. 5 Pharyngeal tonsil (adenoid) |
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Thymus (2 functions)
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1. Forms blood-thymus barrier in cortex
2. Secretes hormones - thymopoietin, thymulin, thymosins 3. Helps develop T lymphocytes 3. Promotes development of T lymphocytes |
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What are lymph nodes?
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Accumulation of lymphocytes in an area
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Lymph nodes functions (2)
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Cleanse the lymph; site of T and B cell activation.
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What are the spleen's functions? (3)
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1. Produces blood cells in extreme anemia
2. Erythrocyte graveyard 3. Stabilizes blood volume |