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23 Cards in this Set
- Front
- Back
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Which groups of antibiotics are highly polar?
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Aminoglycosides
Bacitracin Polymyxin B |
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Which groups of antibiotics are moderately polar?
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Penicillins
Cephalosporins (1st gen) |
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Which groups of antibiotics are moderately lipid soluble?
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Cephalosporins (3rd gen)
Tetracyclines LIncosamides Sulfonamides Nitrofuranes Fluoroquinolones |
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Which groups of antibiotics are highly lipid soluble?
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Rifampin
Chloramphenicol Doxycycline Macrolides |
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Which groups of antibiotics are weak organic acids?
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Penicillins
Cephalosporins Sulfonamides Nitrofurans |
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Which groups of antibiotics are weak organic bases?
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Aminoglycosides
Macrolides Lincosamides Polymyxins Rifampin Fluoroquinolones |
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Which antibiotic group is not pH dependent?
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Chloramphenicol
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Which antibiotic group is amphoteric?
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Tetracyclines
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Which bacteria are the principal challenges to resistance?
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ESKAPE
Enterococcus faecium Staphlococcus aureus Klebsiella pneumoniae Actinobacter baumanii Pseudomonas aeuriginosa Enterobacter spp. |
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Which antibiotics comprise the beta lactams?
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Penicillins
Cephalosporins Imipenem |
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What is the spectrum of activity for the Penicillin G group?
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Gram positive (narrow)
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What is the spectrum of activity for Ampicillin and Amoxycillin?
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Broad spectrum
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Which beta-lactams have broad spectrum?
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Ticarcillin, Ampicillin, and Amoxycillin
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What is the spectrum of activity for the Penicillin G group?
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Gram positive (narrow)
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What is the spectrum of activity for Ampicillin and Amoxycillin?
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Broad spectrum
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Which beta-lactams have broad spectrum?
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Ticarcillin, Ampicillin, and Amoxycillin
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T or F:
Beta lactam antibiotics are good against anaerobes. |
Tru dat!!!
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What is the major adverse effect of the beat lactams? Which specific drugs have this effect?
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Allergic reactions (penicillins and cephalosporins)
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Characterize the disposition of the beta lactams.
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Weak organic acids and highly polar.
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Which beta lactam can cross the blood brain barrier?
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3rd generation cephalosporins
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What are the four groups of penicillins in use today? Which are broad spectrum?
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Penicillin G
Aminopenicillins (broad spectrum) B-lactamase resistant Antipseudomonal (broad spectrum) |
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T or F:
The narrow spectrum penicillins are good against gram negative bacteria. |
False! G+
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What is the spectrum of activity for first generation cephalosporins? 3rd generation?
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Broad for both
1st is more for G+ 3rd more for G- |
