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67 Cards in this Set

  • Front
  • Back
What are the two main divisions of the integument?
Skin and skin derivatives
Name some skin derivatives:
Glands (sweat, sebaceous, mammary)
Hair
Horns
Hooves
Claws
Feathers
Horns
Antlers
Combs
Wattles
What is the largest organ and what is its weight percentage?
Integument! 16% w/w
Name some integument functions:
Barrier – 2 way
Temperature regulation
Secretion
Calcium homeostasis
Protection against UV radiation
Provides for motion and external form
Used in locomotion
Behavior displays - sexual & defense
Mechanical & immune protection
Sensory
ID these regions of the integument
A - Epidermis
B - Dermis
C - Hypodermis
D - Dermal papillae
E - Epidermal pegs
What does skin use to make Vitamin D?
Dehydrocholecalciferol + uv = Vitamin D
ID these dermal structures
A - Sweat gland
B - Hair follicle
C - Sebaceous gland
What is skin contiguous with?
Body holes (mucous membranes)!!
Eyes, ears, urogenital system, respiratory system, both ends of digestive system
What cell type makes up most of the epidermis?
Keratinocytes
What are the layers of the epidermis (from superficial to deep)?
Stratum Corneum
Stratum Lucidum (maybe)
Stratum Granulosum
Stratum Spinosum
Stratum Basale
Which layer contains germinal cells for the epidermis? Which epidermal layer is characterized by actively dividing cells?
Stratum basale for both!
Basal layer of stratum spinosum can also be actively dividing.
What makes the stratum spinosum spiny?
Processing artifact - desmosomes and cell shrinkage
Identifizzle these layas:
A - Stratum basale
B - Stratum spinosum
C - Stratum granulosum
D - Stratum lucidum
E - Stratum corneum
What do keratinocytes in the stratum granulosum contain?
Keratinohyaline granules
Profilagrin
T or F:
Stratum lucidum is only present in thick skin.
True!
Whats is the fancy-ass term for skin flaking?
Desquamate
What are the two types of keratin and give examples of each.
Hard keratin (hooves, horns, feathers, some hair)
Soft keratin (most epidermis and some mucous membranes)
What are the non-keratinocyte component of the epidermis?
Melanocytes
Merkel cells
Dendritic (langerhans) cells
Macrophages
Lymphocytes
What is the embryonic origin of melanocytes? Where are they located?
Neural crest cells BITCHES!
Located in the Stratum Basale YOU KNOW!!!
Ok now its time to play WHERE'S THAT MELANOCYTE!!!
Awww, you lose! It was C
Which cells do melanocytes strive to protect?
Stem cells of stratum basale
Where are most dendritic cells located? Where are most Langerhans cells located?
Different names for the same thing - Dendritic (Langerhans) cells make up 2-4% of epidermal cell population and are located in the stratum spinosum
What are the precursors of Langerhans cells? What is the function of dendritic cells?
From bone marrow precursors. Antigen presenting cells of skin and phagocytic function
What is the possible function of Merkel cells? Where are they abundant?
Possibly mechanoreceptors and may release neuroendocrine substance. Prevalent in stratum basale of oral mucosa and base of hair follicle
What is the region where the epidermis and dermis interdigitate called?
Rete apparatus
What is another name for the dermis? What is its histological morphology?
Corium is dense, irregular CT
What are the two layers of the dermis? What is the tissue composition of each?
Papillary layer (loose to dense irr CT)
Reticular layer (dense irr CT)
T or F
The basement membrane between the dermis and epidermis is sparsely vascularized
False!
T or F:
Both reticular and papillary layers of the dermis contain hair and glands.
False! Only the reticular layer does, yo!
ID these dermal layers
A - Papillary
B - Reticular
T or F:
There are tons-o-immune cells in the papillary layer.
True!
Which of the following are covered by thick skin?
Foot pads
Tongue
Eyelid
Nasal plenum
Teat
Nasal plenum
Teat
Foot pads
Which sweat glands are present in thick skin? Which types of hair?
Merocrine sweat glands.
NO HAIR FOLLICLES!!!
What smooth muscle is attached to hair?
Arrector Pili muscles
Which sweat glands are present in thin skin?
Apocrine sweat glands in all mammals (merocrine in primates)
Steve Urkel knows what kind of skin this is. How do YOU know?
It's thick skin! No hair follicles and presence of stratum lucidum. The stratum corneum is also really really thick.
Hey Kid
What up, Play?
What kinda skin we be in?
Thin Skin!
Check out all the glands and the hair follicle right by Play!
What is the embryologic origin of a hair follicle?
Epidermis! Invades the dermis.
ID these regions of the hair follicle
A - Medulla
B - Cortex
C - Dermal papilla
ID this mess-o-hair parts
Which contains melanocytes?
A - External root sheath
B - Sebaceous gland
C - Outermost cuticle
D - Internal hair sheath
E - Arrector Pili m.
F - Outermost cuticle (sorry put it in twice)
G - Matrix (contains melanocytes)
What is the extent of the root of the hair follicle?
From surface to the bulb
What are the three main layers to a hair shaft?
Outermost cuticle
Cortex
Medulla
What does the hair cortex produce?
Tricohyaline granules and keratin
What are the types of hair follicles (by size and associated structures)?
Primary
Secondary
What are the types of hair follicles by # of follicles exiting from one opening?
Simple
Compound
ID these hair follicles by size/associated structures.
A - Primary
B - Secondary
C - Secondary
T or F:
All hairs have a cortex and medulla
False! Not all have medullae.
Contrast primary and secondary hair follicle.
Secondary is smaller, nearer the surface and has no:
medulla
sweat glands
arrector pili muscles
What type of hair usually has numerous nerve bundles and skeletal muscle associated with it?
Vibrissae (tactile hairs)
What are the main two types of skin glands?
Sebaceous and sweat glands
Describe the secretory mechanism of skin glands.
Sebaceous (holocrine)
Sweat (merorine or eccrine)
Sweat (apocrine)
ID these glands of the skin.
What does each release?
All are sebaceous glands releasing sebum.
Where are eccrine sweat glands mainly found?
Weird places (thick skin)
Foot pads – dogs and cats
Frog of ungulates
Planum nasolabiale in ox
T or F:
You should see no blebbing on merocrine sweat glands.
True!
T or F:
You should see blebbing on eccrine sweat glands.
False! They are the same as merocrine sweat glands!!!
What is sebum composed of?
IGA
FAs
Cholesterol
Vitamin D precursors
T or F:
You should see blebbing on apocrine sweat glands.
True!
T or F:
You should see apocrine sweat glands on hairy skin.
True!
ID 12 and 14
12 - sebaceous sweat gland
14 - Apocrine sweat gland
ID 6 and 7
6 - Sebaceous sweat gland
7 - Apocrine sweat gland
What is the gland morphology of the mammary gland?
Compound tubuloalveolar
Name the (3) types of glands of the anal region.
Circumanal glands
Anal glands
Glands of the anal sac
Where do anal glands open?
Open into anus
T or F:
A good veterinarian can express individual anal glands.
False! I don't care how good you are, you're still expressing anal SACS!
What is the anal gland morphology? What does it secrete in dogs? In cats? In pigs?
Modified tubuloalveolar sweat glands.
Cats/Dogs - lipid
Pig - mucus
What is the secretory mechanism of anal glands? Of glands of the anal sac?
Anal glands are merocrine
Anal sac glands are apocrine to holocrine (sebaceous)
ID the following as:
Anal glands
Circumanal glands
Glands of the anal sac
A - Anal gland
B - Glands of the anal sac
C - Glands of the anal sac
D - Circumanal gland