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21 Cards in this Set
- Front
- Back
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What are the three barriers that invading microorganisms can encounter?
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Physical barriers (skin & etc)
Innate Immunity (inflammation, defensins) Specific immunity (antibodies) |
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What are two possible detriments to the immune system?
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Self-damage (autoimmunity)
Discomfort (inflammation) |
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What cells are involved in acquired immunity?
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Lymphocytes (T and B)
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What cells are involved in innate immunity?
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Macrophages, neutrophils, NK cells
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What is the approximate temporal response for innate immunity? Acquired immunity?
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Innate - hours (2-6h)
Acquired - days (2 to 7d) |
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T or F:
Physical barriers are not a part of acquired immunity. |
True!
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What are some examples of soluble innate factors?
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Cytokines, proteinaceous and non-proteinaceous secretion
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What are some examples of soluble acquired factors?
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Immunoglobins (antibodies)
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How does the GI tract provide innate immunity?
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low pH
Peristalsis bile salts fatty acids |
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How does blood and lymphoid organs provide innate immunity?
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phagocytosis
intracellular killing direct/antibody dependent cytolysis |
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What are components of serum and serous fluid innate immunity?
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Lactoferrin
Transferrin Interferons TNF-a Lysozyme Fibronecten Complement |
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Mucociliary elevator and surfactant action are examples of innate immunity of which region?
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Lungs/trachea
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What is another name for antiviral proteins?
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Interferons
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What are the two subdivisions of the acquired immune response?
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Humoral and cell-mediated response
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What are the two main types of cells involved in the acquired immune response?
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T and B cells
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What are the three main kinds of T-cells?
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Cytotoxic T-cell (Tc)
T helper cells (TH1 and TH2) |
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T or F:
Animals can have an effective humoral response without a thymus. |
False!
Although B-cells don't come from thymus, they still need the T-helper cells for humoral response. |
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What cell type kills virus-infected and tumor cells?
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Cytotoxic-T-cell
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T or F:
Cell-mediated immunity does not involve antibodies. |
True!
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What cell produces antibodies? What cell helps this along?
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Plasma cells produce antibodies; helped by T-helper cell.
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T or F:
Both B and T cells have antibody receptors. |
False (I think); only B-cells do!
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