Brs Dermatology

Front 1

Eczematous Dermatitis

Back 1

pruritic. chemical (contact), atopy. Type 4 hypersensitivity. Acute: spongiosis + vesicles. Subacute. Chronic: acanthosis, hyperkeratosis, lichenification.

Front 2

Neurodermatitis

Back 2

Lichen simplex chronicus. Looks like chronic eszematous dermatitis. Produced by scratching. Casue of pruritus unk.

Front 3

Psoriasis

Back 3

Erythematous papules + plaques w/ silvery scaling. Nonpruritic, extensor surf. Acanthosis + *parakeratosis* + Munro abceses. A/w psoriatic arthritis.

Front 4

Pemphigus vulgaris

Back 4

Intraepidermal bullae oral => skin. Rupture => 2° infection. IgG vs desmoglein => acantholysis. Potentially fatal.

Front 5

Bullous pemphigoid

Back 5

Supepidermal bullae w/ eos. IgG vs BM. Less severe than pemphigus vulgaris

Front 6

Dermatitis herpetiformis

Back 6

Purirtic vesicles. Extensor surf. Microabscesses w/ PMN, eos at tips of dermal papillae. IgA at tips (vs. BM). A/w gluten-sensitive enteropathy. Responds to gluten-free diet.

Front 7

Erythema multiforme

Back 7

multiple types of lesions. Hypersensitivity to infection, drug, dz. Target lesion: central necrosis surr by lighter erythema

Front 8

Ocular albinism

Back 8

Dec melanin

Front 9

Oculocutaneous albinism

Back 9

Eyes, skin, hair. Inc risk: actinic keratosis, basal + SCC, malig melanoma. Turosinase-neg or pos.

Front 10

Vitiligo

Back 10

Acquired, autoimmune. Anti-melanocyte abs or descruction by other factors

Front 11

Ephelis

Back 11

freckle. inc melanin pigment in basal keratinocytes.

Front 12

Lentigo

Back 12

Benign melanocytic hyperplasia.

Front 13

Nevocellular nevus

Back 13

Common mole. Derived from melanocytes. Junctional, Compound, or Intradermal (often non pig)

Front 14

Blue nevus

Back 14

From birth. Highly pigmented melanocytes in dermis.

Front 15

Spitz nevus

Back 15

Benign. Spindle shaped cells. "juvenile melanoma" but not.

Front 16

Dysplastic nevus

Back 16

Disorderly prolif of melanocytes + dermal fibrosis + lympho infiltration. tform => Malignant Melanoma. AD Dysplastic Nevus Syndrome.

Front 17

Lentigo maligna

Back 17

Hutchinson freckle. irreg macular pig lesion on sun-exposed skin. Atypical melanocytes. Tform => Lentigo Maligna Melanoma

Front 18

Molluscum contagiosum

Back 18

Umbilicated, dome-shaped papules. DNA poxvirus. Contact

Front 19

Verruca vulgaris

Back 19

Benign papilloma by HPV (NOT 16, 18, 31, 33). Koilocytes.

Front 20

Acrochordon

Back 20

Skin tag. CT covered w/ stratified squamous

Front 21

Epidermal inclusion cyst

Back 21

Surr by stratified squamous, filled with keratinous material. Dome-shaped nodule. "Sebaceous cyst" but not.

Front 22

Dermatofibroma

Back 22

Benign. Firm nodule. +/- pigmented acanthosis. "Fibrous histoma" if histiocytosis. Intertwining bundles of collagen/fibroblasts.

Front 23

Dermatofibrosarcoma protuberans

Back 23

Slow gorwing, well-differentiated, rarely mets

Front 24

Keratoacanthoma

Back 24

Benign. ~ SCC. Regresses spontaneously

Front 25

Actinic keratosis

Back 25

Premalignant => SCC. Sunlight => rough plaques.

Front 26

Acanthosis nigricans

Back 26

Acanthosis + hyperpig. Marker of visceral malignancy or insulin R

Front 27

Xanthoma

Back 27

Yellow papules of lipid-laden histiocytes. Eyelids, tendons, joints. Hypercholesterolemia.

Front 28

Port-wine stain

Back 28

Purple-red hemangioma. A/w Sturge-Weber

Front 29

Strawberry hemangioma

Back 29

bright-red. > cherry?

Front 30

Cherry hemangioma

Back 30

dome-shaped red papule

Front 31

Cavernous hemangioma

Back 31

large, endothelal-lined in dermis and subdermis

Front 32

Sturge-Weber syn

Back 32

port-wine stain on face, ipsilateral glaucoma, hemangiomas in meninges. Convulsions, MRet, retinal detachment.

Front 33

von Hippel-Lindau dz

Back 33

multiple vascular tumors + other organ sys

Front 34

Granuloma pyogenicum

Back 34

pedunculated lesion. post-trauma

Front 35

Keloid

Back 35

Tumor-like scar from abnormal CT proliferation.

Front 36

SCC

Back 36

Scaling, indurated, ulcerated nodule. Locally invasive, infreq met. Sunlight. Lower part of face (vs BCC). Precursor = actinic keratosis. Histo: Sheets/islands neoplastic cells, keratin pearls.

Front 37

Basal Cell Carcinoma

Back 37

Most common malig skin tumor. Pearly papule w/ overlying telangiectastia. Locally invasive, rare met. Sunlight. Upper part of face (vs SCC). Histo: dark basaloid cells w/ palisade arr of nuc.

Front 38

Malignant melanoma

Back 38

Melanocytes or nevus cells. Sunlight. Radial (no met, in epi + papillary dermis) => vertical growth (reticular dermis, etc).

Front 39

Lentigo maligna melanoma

Back 39

Sunlight. From Lentigo Maligna (Hutchinson freckle)

Front 40

Superficial spreading melanoma

Back 40

Most common melanoma. Irreg border, variegated pigmentation.

Front 41

Nodular melanoma

Back 41

Begins with vertical growth => worst prognosis.

Front 42

Acral-lentiginous melanoma

Back 42

Hands + feet of dark-skinned people.