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36 Cards in this Set

  • Front
  • Back
risk factors for breast cancer
early menarche
late menopause
nuligravida/1st after 30
hormone replacement w/ EtOH use
when should high risk pt start screening with mammography
10 yrs before relative dx or 25
when to start mammography on hodgkins pt.
8 years after tx
sensitivity of mammograms
75-90%
solid rubbery mass
fibroadenoma
most common breast mass
benign cyst
where are most breast cancers found
upper lateral quadrant
biopsy guided by video
stereotactic biopsies
example of a prognostic factor
lymph node (gives info on clinical outcomes, independent of therapy)
negative estrogen/progesterone receptors are assx with what prognosis
poor
what is the gail model
prediction of first breast cancer
low levels of what vitamin can lead to increased risk of breast cancer
vitamin E
aggresive genetic form of breast cancer
HER2/neu
high risk women that start mammograms early
family hx (start 10 yr after dx)
hx of hodgkins (start 8 yr after tx)
large or small breasts have better sensitivity with mammogram
small
rubbery mass in breast
fibroadenoma
nontender mass in breast
CA?
breast cancer with 100% cure rate
DCIS
two reasons to biopsy
palpable mass
abnormal mammogram
most common method of biopsy
stereotactic (video guided)
most important factor of staging breast cancer
N: lymph node involvement
most common site of lymph drainage from the breast
axilla
oncogenes that are assx with poor prognosis
HER-2/neu
ER-B-2
EGF
myc
poor prognostic indicators
large tumor
oncogenes
negative P and E receptors
hormone receptor assay is a prognostic or predictive factor
predictive (info on response to specific treatment)
lymph node status is a prognostic of predictive factor
prognostic (info on overall outcome regardless of specific therapy)
breast surgery that requires radiation
lumpectomy
contraindications to lumpectomy
pregnancy
previous XRT to breast
multicentric disease
SLE/RA
lumpectomy versus mastectomy in terms of survival
same
radiation therapy for breast cancer must be administered how often
daily
tx strategy for severe disease
chemo (always multi-drug)
hormone therapy drug classes used in breast cancer
SERMS
aromatase inhibitors
complications of breast cancer tx
secondary malignancy
ovarian failure (menopause)
lymphedema
most breast cancer pt. have or do not have a family hx of breast cancer
do not have
most common breast mass
cyst (fibrocystic change)
follow up schedule for breast cancer survivors
every 3 mo for 3 years then
every 6 mo for 2 years then
every year