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121 Cards in this Set
- Front
- Back
head fold 1) 2) |
ventral "swing" of heart and oropharyngeal membrane closure of foregut |
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formation of branchial apparatus: 1) 2) |
1) neural crest cells 2) cephalic paraxial mesoderm |
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source of all connective tissues including skeleton |
neural crest cells |
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source of all skeletal muscles |
cephalic paraxial mesoderm |
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if drugs/alcohol is involved, you usually see problems in the |
face |
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branchial apparatus includes these 4 things: |
branchial arches branchial grooves branchial pouches branchial membrane |
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there are ____ branchial arches |
6 |
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the __ arch is separated into 2 prominences: ___ & ___ |
first maxillary mandibular |
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there are ___ external grooves separating each arch |
4 |
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ectodermal lined depression |
stomodeum |
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separated from foregut by |
oropharyngeal membrane |
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forms the anterior 2/3 of the tongues |
stomodeum |
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the remnant of the oropharyngeal membrane |
palatoglossal arch |
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four internal evaginations of endoderm separating each branchial arch |
pharyngeal pouches |
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meeting of ectoderm of branchial groove w/ endoderm of pharyngeal pouch |
branchial membrane |
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3 structural components of a typical branchial arch |
ectodermal outer covering endodermal inner lining mesenchymal core |
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ectodermal outer covering |
epidermis |
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endodermal inner lining |
mucosal |
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mesenchymal core |
branchiomeric mesenchyme |
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mesenchymal core contains: |
1) blood vessel (endothelium of an aortic arch) 2) cartilaginous bar (forms from neural crest cells) 3) muscular component (forms from cephalic paraxial mesoderm (somitomeres)) 4) cranial nerve |
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the cartilage in each arch that forms from neural crest cells give rise to |
adult structures |
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branchial groove 1 gives rise to |
external acoustic canal |
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branchial grooves 2-4 give rise to |
cervical sinus (usually regresses) |
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maxillary does/doesn't have cartilage associated w/ it |
does not |
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1) Meckel's cartilage 2) dorsal part forms malleus & incus by _____ ossification 3) ventral portion regresses 4) _____ forms by intramembranous ossification |
mandibular prominence
-endochondral mandible |
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forms maxilla, zygomatic bone, & squamous portion of temporal bone by intramembranous bone formation |
maxillary prominence |
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branchial arch 1 gives rise to: |
mandibular prominence maxillary prominence |
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malleus, incus, and mandible come from which arch |
arch 1 |
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maxilla, zygomatic bone, and squamous portion of temporal bone come from which arch |
arch 1 |
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has - Reichert's cartilage - forms stapes, styloid process, upper 1/2 of hyoid bone by endochondral bone formation |
branchial arch 2 |
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which arch forms lower half of hyoid bone (by ____ bone formation) |
branchial arch 3 endochondral |
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which arches form cartilage of larynx (except epiglottis) |
arches 4 & 6 |
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branchial arch 1 innervation |
maxillary & mandibular divisions of trigeminal nerve (V2, V3) |
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branchial arch 2 innervation |
facial nerve (CN VII) |
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branchial arch 3 innervation |
glossopharyngeal n (CN IX) |
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branchial arch 4 |
superior laryngeal branch of vagus nerve (CN X) |
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branchial arch 6 derived structures innervation |
recurrent laryngeal branch of vagus nerve (CN X) |
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branchial muscles come from |
cephalic paraxial somitic mesoderm |
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branchial muscles innervation |
efferent branches of cranial nerves to branchial arches |
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arch ___: muscles of mastication mylohyoid anterior belly of the digastric tensor tympani tensor veli palatini |
branchial arch 1 |
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branchial arch 1 innervation |
V3 |
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arch __ : muscles of facial expression stylohyoid posterior belly of the digastric stapedius |
arch 2 |
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branchial arch 2 innerv |
VII |
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arch __: stylopharyngeus |
arch 3
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arch 3 innerv |
IX |
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arch __ : cricothyroid levator veli palatini constrictors of pharynx palatoglossus |
4 |
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arch 4 innerv |
superior laryngeal branch of vagus |
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arch __: intrinsic muscles of larynx |
6 |
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arch 6 innerv |
recurrent laryngeal branch of vaugs |
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- tubotympanic recess - forms pharyngotympanic canal & cavity of middle ear |
pharyngeal pouch 1 |
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epithelium of palatine tonsil and tonsilar crypts |
pharyngeal pouch 2 |
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-dorsal portion- inferior parathyroid glands - ventral portion- epithelial reticulum of thymus gland |
pharyngeal pouch 3 |
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-dorsal portion- superior parathyroid glands -ventral portion 1) ultimobranchial body 2) associates w/ neural crest cells to form parafollicular (c-cells) of thyroid gland
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pharyngeal pouch 4 |
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pharyngeal pouch structures develop ____ |
bilaterally |
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thyroid gland is _____ derived form pharyngeal pouches! |
not |
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Thyroid diverticulum 1. endodermal-lined evagination 2. just ____ to median tongue bud 3. ________ (proximal opening of thyroglossal duct) |
caudal foramen cecum |
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Descent of thyroid gland into neck 1) ____ (narrow tube connecting thyroid gland to tongue) 2) ___ structure 3) most ____ structure
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thyroglossal duct midline anterior |
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diverticulum- ___ and ____ down tongue and into neck |
expands elongates |
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thyroid gland is/isn't derived from branchial apparatus |
is not |
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congenital malformations of Thyroid gland |
1) thyroglossal duct cyst 2) thyroglossal duct sinus 3) ectopic thyroid gland |
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cyst in thyroglossal duct can form an opening on surface |
thyroglossal duct sinus |
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when the thyroid doesn't descent to normal position, can be located anywhere along the path of descent |
ectopic thyroid gland |
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sites of ectopic thyroid tissue |
lingual thyroid foramen cecum of tongue accessory thyroid tissue pyramidal lobe of thyroid gland |
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these two sites of ectopic thyroid tissue are associated with downs syndrome |
lingual thyroid/forame cecum |
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most common congenital cause of a neck mass |
branchial cleft cysts |
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accounts for 20% of all neck masses in children (2-3% of cases are bilateral) |
branchial cleft cysts |
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branchial malformations include |
- branchial sinus, fistula or cyst -first arch syndrome - digeorge syndrome - ectopic glandular tissue |
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remnant of cervical sinus not midline structures |
branchial sinus, fistulas or cysts |
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branchial malformations are ___ |
lateral |
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cervical sinus would be along the ____ |
sternomastoid |
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complete branchial fistula connects pharynx w/ ___ |
exterior |
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- malformations of the ear, mandible, zygoma and palate - due to insufficient migration of neural crest cells into the first branchial arch |
first arch syndrome |
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DiGeorge Syndrome: 1) lack of ____ glands and ___ glands 2) facial abnormalities: ___ ears, ___ mouth 3) defects in ___ of heart and great vessels |
parathyroid, thmus low-set, small outflow tract |
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the development of all the organs involved in Digeorge syndrome is dependent on ________ to the region of _______ |
migration of neural crest cells pharyngeal pouches |
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all pouches are derived from |
endoderm |
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neural crest defect would affect just as much as endoderm defect |
true
|
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stomodeum 1. ___ depression 2. forms ______ of oral cavity 3. ___ pouch- anterior lobe of pituitary; glandular outgrowth of ectoderm from the stomodeum of the embryo 4. oropharyngeal membrane |
ectoderm-lined anterior 2/3 Rathke's |
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all of the face is mostly associated w/ which arch |
1 |
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frontal prominence of head includes |
head/forehead region |
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rathke's pouch (aka hypopysial diverticulum) gives rise to |
anterior pituitary |
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five facial primordia |
frontonasal prominence maxillary prominences (paired) mandibular prominences (paired) |
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the 5 facial prominences are formed from the proliferation and migration of _____ |
neural crest cells |
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the ____ is the major source of connective tissue components, including cartilage, bone, and ligaments in the ___ and ____ regions |
neural crest face oral |
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stomodeum five facial primordia nasal placodes medial and lateral nasal prominences nasolacrimal groove intermaxillary segment cutaneous sensory innerv muscles of facial expression |
development of face |
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nasolacrimal groove: forms between ______ processes and adjacent ____ swelling |
lateral nasal maxillary |
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placode = |
thickening of surface ectoderm |
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nasal placodes begin to indent and form ___ |
pits |
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you have ___ and ___ nasal prominences around the pits |
medial lateral |
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pits migrate ____ toward each other |
medially |
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you can see clefts in babies between the ____ |
pits |
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nasolacrimal groove: connects ___ side of eye w/ ____ |
medial nasal cavity |
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formed by fusion of paired medial nasal prominences |
intermaxillary segment |
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forms philtrum of lip fleshy nasal septum premaxillary part of maxilla primary palate |
intermaxillary segment |
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intermaxillary segment forms ____ palate |
primary |
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extension of intermaxillary segment |
primary palate |
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frontonasal prominence innerv |
V1 (ophthalmic division of trigeminal) |
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maxillary prominence innerv |
V2 (maxillary div of trigeminal) |
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mandibular prominence innerv |
V3 (mandibular ldiv of trigeminal) |
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face has sensory inner by branches of the |
trigeminal |
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muscles of facial expression are located in _____ (hyoid) branchial arch |
second |
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muscles of facial expression are inner by |
facial nerve (VII) |
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muscles of facial expression associated w/ arch __ |
2 |
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nasal pits and sacs: ______ - lined depressions |
ectoderm |
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oronasal membrane: 1. rupture of _____ 2. continuity between ____ and ___ cavities |
membrane nasal, oral |
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development of palate:
|
primary and secondary palate |
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primary palate: forms as part of _____ segment |
intermaxillary |
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secondary palate: - forms as ___ shelves (lateral palatine processes) that lift from ____ prominences |
paired maxillary |
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secondary palate: forms by fusion of: |
paired lateral palatine process and nasal septum |
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formed from neural crest in frontonasal and medial nasal processes |
nasal septum |
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separates oral and nasal cavities (except in region of pharynx) |
palate |
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shelves grow from proliferation of ____ |
neural crest cells |
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primary palate forms from |
intermaxillary segment |
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secondary palate forms from |
palatal shelves & nasal septum |
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incisive foramen is landmark between ___ and ___ palate |
primary and secondary |
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makes up majority of adult palate |
secondary palate |
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anterior cleft malformations: 1. cleft ___ 2. incomplete fusion of _____ with _____ |
lip maxillary prominence, medial nasal prominence |
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posterior cleft malformation: 1. cleft ____ 2. incomplete fusion of ______ and ____ |
palate lateral palatine processes, nasal septum |
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epidemiology of cleft lip: 1/1000 births occurs more frequently in ____ (80%) incidence increases slightly w/ ____ age |
males maternal |
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epidemiology of cleft palate: - 1/2500 births - occurs more frequently in ___ (67%) (palatal shelves fuse 1 week later in them) - not related to maternal age
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females |
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______ drugs (phenobarbital and diphenylhydantoin) during pregnancy increases risk of cleft lip and cleft palate |
anticonvulsant |
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causes of cleft palate: - _____ of palatal shelves -failure of shelves to _____ -inhibition of the fusion process itself - failure of the ___ to drop btwn the shelves because of microagnathia |
smallness elevate tongue |