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48 Cards in this Set

  • Front
  • Back
Pituitary Adenoma
Anterior Pituitary tumor
Rare in Children
May be endocrine active
Craniopharyngioma
Benign congenital: mostly in children
Not endocrine active but does expand upward
Hypothalamic Syndrome/Hypopituitarism
Compression of pituitary stalk therefore tropic hormones from hypothalamus aren't released which causes decreased pituitary hormones
Hypothalamic Hamartoma
Mass near hypothalamus
Causes change in diet, hyperactivity, euphoria, headaches and FTT
What nucleus in Hypothalamus regulates temp?
Anterior N.
What hypothalamic nuclei regulate volume and osmolarity?
SFO (Ang II), OVLT (Na) and SON (ADH)
What hypothalamic n. receives food intake inputs and what n. send outputs?
Arcuate N. receives inputs and PVN/Lat.N. send output
Kluver- Bucy Syndrome
Bilateral Temporal Lobectomy
Flat emotions, lack of fear, hypersexuality, orally fixated, visual agnosia
How does damage to the hippocampus affect memory?
Inability to form new memories
Stimulation of Amygdala produces...
Fear, frustration, anger, rage and violence
What part of the limbic system recognizes fear in others?
Left Amygdala
Urbach-Wiethe Disease
Bilateral calcification near the amygdala produces a human Kluver Bucey Syndrome
What receptor is responsible for rewarding feelings?
Dopamine D2 Receptor
Reward Deficiency Syndrome
Decrease in D2 Receptor
Impulsive behavior, compulsive behavior, personality disorders and addictive behavior
What part of the cingulate cortex regulates attention to pain?
Anterior Cingulate Cortex
Korsakoff Syndrome
Damage to mamillary bodies as a result of chronic alcoholism
Have difficulty forming new memories, temperospacial disorientation, and confabulation
Autonomic Neurotransmitters
ACh, NE and E
What neurons are shared between autonomic and somatic neurons?
Secondary Neurons
Sympathetic afferents control...
visceral pain
Parasympathetic afferents control...
unconscious reflexes
Neuroblastoma
Adrenal Gland Tumor
Pheochromocytoma
Tumor releasing catecholamines
Orthostatic Intolerance
Increased heart rate with standing, light headedness, abnormal sweating
Neurally-mediated syncope
fainting with standing
Explicit Memory
Conscious recollection of facts and experiences
Where is explicit memory located?
Short term: Hippocampus
Long term: Cortex
Implicit Memory
Unconscious, emotional and motor memory
Where is implicit memory located?
Striatum, Cerebellum and Amygdala
What type of amnesia would result from bilateral removal of the Hippocampus?
Anterograde- no new explicit memories
Part of brain activated during Working Memory
Dorsal and lateral prefrontal cortex
Damage results in problems planning, solving problems and maintaining attention
Impulsivity is regulated in what part of the brain?
Orbital and medial prefrontal cortex
Long Term Potentiation (neuroplasticity)
Increasing the number of AMPA receptors to strengthen existing synapses and produce new synapses: increases strength of communication between two neurons
Protein in neurofibrillary tangles
Tau
Alzheimer's Diagnostic hallmarks
neuronal loss, neurofibrillary tangles and amyloid plaques
Biggest risk factor for Alzheimers
Age
Mild Cognitive Impairment
Term for individuals with memory loss but no other cognitive decline
Alzheimer's susceptibility gene
ApoE
Neurotransmitter implicated in Alzheimer's
ACh
Cortical Dementias
Alzheimer's, Pick's Disease, Lewy Body Dementia
Subcortical Dementias
Parkinson's, Huntington's, Wilson's, Progressive supranuclear palsy, spinocerebellar degeneration, Olivo-ponto-cerebellar degeneration and dementia secondary to MS
Characteristics of subcortical dementias
mental and motor slowing
Pick's Disease
Rare
Frontal and Ant. Temporal lobe atrophy
Degeneration leads to disinhibition and hyperorality
Normal Pressure Hydrocephalus
Clinical symptoms:
Cognitive disturbance, gait apraxia, and urinary incontinence
Rett's Disorder
Normal development for first 5mos. of life but then gradual deceleration of head growth accompanied by loss of purposeful hand skills and hand wringing
Almost exclusively female
Childhood Disintegrative Disorder
Normal development for first two years but between ages 2 and 10 there is loss of bowel and bladder control in addition to decreased motor and social skills
Asperger Syndrome
Autistic disorder characterized by social impairment and the restrictive/repetitive behavior
**No language delay or cognitive impairment
Bipolar Disorder
One or more manic or misxed episodes
Mania: DIGFAST
Distractibility, Impulsive behavior, grandiosity, fast or racing thoughts, increased activity, decreased sleep and talking rapidly