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39 Cards in this Set

  • Front
  • Back
Central Nervous System (CNS)
Brain and spinal cord
•Processing sensory info
•Interpreting/storing info
•Making decisions
•Sending out motor commands
Peripheral Nervous System (PNS)
All nerves outside of bones of skull and spinal cord

•Carries info between body and CNS

•Somatic Nervous System
- Sensation and movement
- Cranial and spinal nerves

•Autonomic Nervous System
- Sympathetic (fight or flight)
- Parasympathetic (rest and digest)
Protection of CNS
Brain encased in bone (skull)

Spine protected by vertebrate bones
Phrenology
Study of correlation between personality and character with skull shape
Franz Joseph gall
Austrian anatomist (1700s)
Brain had 35 domains for specific mental functions
Domains grow as used (would cause enlarged skull bumps)
Ablation technique
Lesions/damage of parts of the brain
PET: position emission tomography
Based on PC tomography x ray images of radio-nucleotides emissions linked to specific chemicals
fMRI: functional magnetic resonance imaging
Measures ratio of oxygenated to deoxygenated hemoglobin
This measurement relays brain activity
"Active" brains have high ratios
Ectoderm
Outer body tissues (nails, hair)
Nervous system (including neurons in the CNS and PNS)
Blastocyte
Forms 5 days post fertilization when 100 embryonic cells form
Embryonic disc
Baby to be
15 days post fertilization: Blastocyte implants onto uterus
Placenta, sac and fluid
Remaining embryonic cells that do not compose blastocyte or embryonic disc
15 days post fertilization
Endoderm + mesoderm
Inner body tissue (organ, muscle, bone)
Neural plate
18 days post fertilization
Ectoderm thickens to form plate
Neural grove
21 days post fertilization
Bottom of neural plate grows rapidly to form grove
Neural tube
22 days post fertilization
Tops of neural grove fuse to form tube
Space inside tube = ventricular space and fills with CSF
Spina bifida
Lower portion of neural tube does not fuse
Will result in motor problems
Anencephaly
Top portion of neural tube does not fuse (no forebrain)
Will result in death
28 days post fertilization
Fore, mid, and hind brain visible
24 days post fertilization
Brain and heart development begin
100 days post fertilization
Brain looks human
Forebrain bulge
Telencephalon: cortex, limbic system
Diencephalon: thalamus, hypothalamus
Lateral and 3rd ventricles

Bulge at top of vertebrate
Midbrain bulge (Mesencephalon)
Tectum (colliculi)
Tegmentum
Cerebral aqueduct

2nd bulge in vertebrate
Hindbrain bulge
Pons
Cerebellum
Medulla
4th ventricle

3rd bulge in vertebrate
Spinal Cord Region
Central canal

Bottom of vertebrate
Cell birth (neurogenesis, gliogenesis)
First stage of brain development (prenatal)

Multipotent stem cells -->
precursor cells -->
specialized blasts -->
• nueroblast
• gliobast
Cell migration
Second stage of brain development (prenatal)

Once new cells stop dividing they are directed by signals from radial glia cells to final location in brain or spinal cord
Cell differentiation
Third stage of brain development (prenatal)

Nueroblasts become specific types of neurons
Cell maturation
Fourth stage of brain development (postnatal)

Somas remain stationary as ...

Axonal growth: growth cone of axon is repelled, by repulsion factors, or attracted, by chemotrophic factors, released by other cells to reach its target to initiate synapse formation

Dendritic growth: dendrites grow to provide surface area for synaptic connections; growth of dendrites corresponds with emergence of associated behavior

Plasticity
Ability of brain to adapt to the world by changing physical/chemical properties and functions
• environmental adaption
• injury compensation
Lance-Jones and Landmesser experiment
During experiment the spinal cord of a chick was reversed, however axons still grew to proper locations. This proving the attraction/repulsion mechanism by which axons mature.
Synaptogenesis
Fifth stage of development (postnatal)

Formation of new synapses
Synaptic development progressed by genetic programming and environmental cues
Synaptic pruning
Sixth stage of brain development (prenatal)

Fine tuning of connections through apoptosis (cell death)

Synaptic pruning: thinning of cortex from front to back
Myeologenesis
Seventh stage of brain development (postnatal)

Axon myelination: coating of axon in fatty cells
• in the CNS, the fatty cells are, oligodendrocytes
• in the PNS, the fatty cells are, Schwann cells

Cortex myelination: begins post birth and continues for at least 20 years
• simple function regions are myelinated first, then complex function regions are myelinated afterwards
"Critical Period" of postnatal development
Usually during synaptogenosis

During the CP sensory input is essential to development of synapses
• more sensory input = improved function
Strabismus
Abnormality in which children can not properly align their eyes, due to a lack of around-eye muscle coordination
• lack of coordination is a result of a lack of muscle usage during Critical Period of vision development
Hebb Experiment (1947)
Rats raised in standard cage vs. Rats raised in "enriched environment"
• Rats raised in "enriched environment" exhibit more dendritic branches, synapses, and astrocytes
• Same rats also show better sensory motor coordination and cognitive abilities

Experiment proved point that stimulating environments maximize development
Sensory function
Get/integrate info about the world
Motor function
Control movements