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37 Cards in this Set

  • Front
  • Back

Phenolic

-Compound that contains a phenolic group


-Actions: antioxidant, anti-inflammatory, anticancer, antimicrobial


-Herbs: abundant in nature especially in plants


-Readily accept/donate electrons

Phenylpropanoids

-Derived from phenylalanine


-Used to make hydroxy cinnamic acids which are precursors for phenylpropene, polyphenol, and coumarins

Hydroxy cinnamic acid

-Derived from phenylpropanoid; has a carboxylic acid group attached to it


-Actions: antioxidant, anti-inflammatory, anticancer, antidiabetic


-Caffeic acid, ferulic acid, coumaric acids


-Rosmarinic acid (Antioxidant, anticancer, anti-inflammatory, anti-allergic)

Phenylpropene

-Derived from hydroxy cinnamic acid; has a 3 carbon side chain with a double bond


-Actions: carminative, antimicrobial


-Herbs: Anise, fennel, clove


-Long-term use -> hepatotoxic


Polyphenol

-Has more than one phenolic group


-Precursor of flavonoids, curcuminoids, stilbenoids, and lignans

Flavinoids

-Polyphenol with 2 phenyl rings and heterocyclic ring


-Derivatives of flavones, isoflavones, flavanol, anthocyanidins

Curcuminoids

-Derived from polyphenol; phenylpropanoid dimer


-Actions: antioxidant, anti-inflammatory, anticancer, hepatoprotective, chologogue


-Curcumin (Tumeric)

Stilbenoids

-polyphenol


-Actions: antioxidant, anti-aging, phytoestrogenic


-Resveratrol - grapes, blueberries, peanuts

Lignans

-Derived from polyphenol


-Actions: phytoestrogenic, antioxidant, anticancer


-Secolsolariciresinol


-Flax, sesame seeds

Flavones

-Flavonoids with a ketone


-Actions: Antioxidant, anti-inflammatory, anticancer, antihistimine


-quercin


-onions, citrus (hesperetin, ,nariginenin), leafy vegetables, tea

Isoflavones

-Actions: phytoestrogenic, antioxidant, anticancer


-Genistein, daidzein


-soy

Phenolic acids

-Actions vary depending on structure


-gallic acid (tannins), salicylic acid, benzoic acid, ellagic acid (pomegranate)

Hydroquinone

-Drived from a phenol


-Action: urinary astringent, antimicrobial


-Arbutin found in bearberry


-Generate free radicals

Flavan-3-ols

-Lack ketone and double bond


-Actions: antioxidant, anticancer, UV absorbent


-Catechin, epecatechin


-Tea, chocolate

Anthocyanidins

-Derivative of flavonoids


-Actions: antioxidant, anticancer, anti-inflammatory, anti-adherence


-High amounts in flowers and berries

Tannins

-Phenolic compound that binds to and precipitates another compound


-Actions: Astringent, antimicrobial, antioxidant


-Hydrolyzable tannins: gallic acid glycosides, ellagic acid glycosides - witch hazel, oak, pomegranate, tea


-Condensed tannins (non-hydrolyzable): proanthocyanidins - blueberries, elderberries, grapes


-High amounts can irritate bowels, liver, and kidneys

Flavonolignans

-Derived from lignan


-Actions: hepatoprotective, antioxidant, inhibits P-glycoproteins


-Silybin (Milk thistle)


-barberry

Coumarins

-Derived from hydroxy cinnamic acid


-Actions: Antispasmodic, smooth muscle relaxant, lymphatic, antiderma, antihypertensive


-Courmarin, umbelliferone, scopoietin, aesculin


-Red clover, cinnamon, crampbark, horse chestnut


-Caution: anticoagulent, hepatoxic

Furanocoumarin

-Derived from coumarins


-Contains furan ring


-Phytochemicals: psoralen, bergamottin, aflatoxin


-rue, grapefruit, wild parsnip, giant hogweed


-Caution: Photosensitizer, grapefruit inhibits phase I liver detox, hepatotoxic

Pthalides

-Derived from coumarins


-Has a lactone group


-Actions: Relax smooth muscles, lowers blood pressure


-3-n-butylphthalide


-Celery, garden angelica, don quay

Benzoquinones

-

Napthoquinone

-quinone fused to benzene ring


-Actions: antimicrobial, vermifuge, dark red brown pigments, antioxidant/provident, laxative


-Juglone, Vit K, Coenzyme Q10


-Black walnut, henna

Quinone

-Hydroquinone + benzoquinone

Anthraquinones

-Quinone with two benzene rings


-Actions: Stimulating laxative, antimicrobial, possible anti-depressant


-Anthraquinone, sennoside A


-Senna, rhubarb root, aloe resin, St. John's wort


-Can affect electrolyte balance and interact with drugs

Alkaloids

-Derived from phenylalanine

Protoalkaloids

-Actions: Mixed effects on NS, sympathomemetic, hallucinogenic


-Mescaline, ephedrine


-Ephedra, peyote, San Pedro cactus, bitter orange


-Caution: pregnancy and blood pressure

Indoles

-Alkaloid with an indole group


-derived from tryptophan


-Action: interacts with serotonin receptors


-DMT, serotonin 5 hydroxytryptamine, ergotamine, reserpine

Piperidine

-Actions: mixed effects on NS


-Indian tobacco (lobeline - induces vomiting), black pepper (piperidine - carminative, increases drug absorption), poison hemlock (conine - paralysis)


-Caution: pregnancy


Imidazole

-pilcarpine (jaborandi)


-Action: stimulates parasympathetic NS

Pyrrolidine & pyridine

-Nicotinc acid (pyridine)


-Nicotine (Pyridine & pyrrolidine)

Tropanes

-Effects NS


-Actions: analgesic, anticholinergic, sympathomimetic


-Tropane alkaloid, atropine, scopolamine, hygrine


-Deadly nightshade, jimson weed, coca


-Caution: narrow therapeutic index, death

Isoquinolines

-Actions: Antimicrobial, bitter, antimalarial


-Berberine, hydrastine


-goldenseal, barberry, oregon grape


Quinolines

-Actions: antimicrobial, antimalarial, bitter


-Quinine, quinoline


-Cinchona tree, tonic water

Quinolizidine alkaloids

-Actions: emmenogogue, antiarrhythimic


-N-methylcystisine, sparteine


-Blue cohosh

Purine

-Actions: stimulant, diuretic, bronchodilator


-caffeine, theobromine


-Coffee, tea, chocolate


-Caution: pregnancy

Pyrrolizidine

-Actions: unknown


-Symphytine


-Comfrey, borage, coltsfoot


-Caution: hepatotoxic

Organosulfur compounds

-Organic compound that contains sulfur


-Actions: antimicrobial, antioxidant, anticancer, detoxifier


-suloraphane, allicin, amino acids


-onions, garlic, scallions, brussel sprouts


-Induces phase II liver detox