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31 Cards in this Set
- Front
- Back
mesenchyme
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where cartilage, bone derived from
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cartilage
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support and protect soft tisue, sliding surface joints, dev and growth of long bones, repair of bone. avascular. ECM and high water content. cells nourised by diffusion
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perichondrium
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capillary sheath of dense CT.
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chondroblast
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syn and deposit ECM and fibers, not yet trapped in matrix
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chondrocytes
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mature cells, surrounded by matrix, spaces called lacunae
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lacunae
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chondrocytes reside, usually several cells one lacuna.
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components of ECM
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collagen II, hyaluronic acid, proteoglycans, glycoproteins
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elastic cart
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high content of elastic fibers, gives flex and resiliecny, ear, auditory or eustachian tube, epiglottis
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fibrocartilage
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prominent bundles of collagen I which gives it tensile strength, found in frictional forces such as intervertebral discs, pubic symphysis, TMJ
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ground substance
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btw cells and collagen and elastic fibers. highly hydrated gel with proteoglycans.
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proteoglycans in cartilage
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polypep chains linked with GAGs (chondrotin sulfates and keratan sulfates) bind to hyaluronic acid core.
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hyaline cartilage
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most widespread type,
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endochondral bone formation
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replacing hyaline cart model with bone
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bone vs cart
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bone presence of inorganic Ca salts in ground, makes matrix rigid, Ca reserve for body, highly vascularized, high tensile strength
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3 types of cells in bone
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osteoblast, osteocytes, osteoclasts
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osteoblasts
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produce collagen I, ground sub of bone. found at surfaces and arise from periosteum and endosteum
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osteocytes
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dervied vrom osteoblasts, cells trapped within matrix, long cytoplasmic processes canaliculi
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osteoclasts
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large mulit-nucleated cells arise from fusion of bone marrow precursors, role in bone remodeling, and resorb mineral and organic components
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periosteum
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outer surface of bone covered by fibroblast like cells.
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osteoprogenitor cell
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differentiate into osteoblast
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endosteum
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thin layer of cell
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primary component of bone
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hydroxyapatite
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primary bone
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1st bone formed by fetus, repair bone, woven or immature bone, tooth sockets, tendon insertions
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spongy bone
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cancallous bone: made up of interconnected trabeculae form mesh with marrow spaces
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compact bone
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dense bone: solid which is a result of primary to secondary, defined organization lamellae
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func unit of bone
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haversian system, formed from outward in due to deposition of bone by osteoblast which then become osteocytes. continually resorbed and remodeled
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bone formation
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intramembranous ossification and endochondral ossification
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intramembranous ossification
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skull and face, mesenchymal cells to osteoblasts, deposition of minerals within matrix turns into bone, appositional growth at outer
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endochondral ossification
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hyaline cart is replaced with bone, longitudianl growth of long bones.
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5 zones in epiphyseal plate
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resting, proliferative, hypertrophic cartilage, calcified cartilage, ossification.
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bone repair
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mesenchymal cells differentiate to chondroblasts and osteoblasts. cartilage formation and bone differentiation and cartilage matrix will be replaced with bone matrix.
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