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31 Cards in this Set

  • Front
  • Back
where cartilage, bone derived from
support and protect soft tisue, sliding surface joints, dev and growth of long bones, repair of bone. avascular. ECM and high water content. cells nourised by diffusion
capillary sheath of dense CT.
syn and deposit ECM and fibers, not yet trapped in matrix
mature cells, surrounded by matrix, spaces called lacunae
chondrocytes reside, usually several cells one lacuna.
components of ECM
collagen II, hyaluronic acid, proteoglycans, glycoproteins
elastic cart
high content of elastic fibers, gives flex and resiliecny, ear, auditory or eustachian tube, epiglottis
prominent bundles of collagen I which gives it tensile strength, found in frictional forces such as intervertebral discs, pubic symphysis, TMJ
ground substance
btw cells and collagen and elastic fibers. highly hydrated gel with proteoglycans.
proteoglycans in cartilage
polypep chains linked with GAGs (chondrotin sulfates and keratan sulfates) bind to hyaluronic acid core.
hyaline cartilage
most widespread type,
endochondral bone formation
replacing hyaline cart model with bone
bone vs cart
bone presence of inorganic Ca salts in ground, makes matrix rigid, Ca reserve for body, highly vascularized, high tensile strength
3 types of cells in bone
osteoblast, osteocytes, osteoclasts
produce collagen I, ground sub of bone. found at surfaces and arise from periosteum and endosteum
dervied vrom osteoblasts, cells trapped within matrix, long cytoplasmic processes canaliculi
large mulit-nucleated cells arise from fusion of bone marrow precursors, role in bone remodeling, and resorb mineral and organic components
outer surface of bone covered by fibroblast like cells.
osteoprogenitor cell
differentiate into osteoblast
thin layer of cell
primary component of bone
primary bone
1st bone formed by fetus, repair bone, woven or immature bone, tooth sockets, tendon insertions
spongy bone
cancallous bone: made up of interconnected trabeculae form mesh with marrow spaces
compact bone
dense bone: solid which is a result of primary to secondary, defined organization lamellae
func unit of bone
haversian system, formed from outward in due to deposition of bone by osteoblast which then become osteocytes. continually resorbed and remodeled
bone formation
intramembranous ossification and endochondral ossification
intramembranous ossification
skull and face, mesenchymal cells to osteoblasts, deposition of minerals within matrix turns into bone, appositional growth at outer
endochondral ossification
hyaline cart is replaced with bone, longitudianl growth of long bones.
5 zones in epiphyseal plate
resting, proliferative, hypertrophic cartilage, calcified cartilage, ossification.
bone repair
mesenchymal cells differentiate to chondroblasts and osteoblasts. cartilage formation and bone differentiation and cartilage matrix will be replaced with bone matrix.