Bone And Cartilage

Front 1

mesenchyme

Back 1

where cartilage, bone derived from

Front 2

cartilage

Back 2

support and protect soft tisue, sliding surface joints, dev and growth of long bones, repair of bone. avascular. ECM and high water content. cells nourised by diffusion

Front 3

perichondrium

Back 3

capillary sheath of dense CT.

Front 4

chondroblast

Back 4

syn and deposit ECM and fibers, not yet trapped in matrix

Front 5

chondrocytes

Back 5

mature cells, surrounded by matrix, spaces called lacunae

Front 6

lacunae

Back 6

chondrocytes reside, usually several cells one lacuna.

Front 7

components of ECM

Back 7

collagen II, hyaluronic acid, proteoglycans, glycoproteins

Front 8

elastic cart

Back 8

high content of elastic fibers, gives flex and resiliecny, ear, auditory or eustachian tube, epiglottis

Front 9

fibrocartilage

Back 9

prominent bundles of collagen I which gives it tensile strength, found in frictional forces such as intervertebral discs, pubic symphysis, TMJ

Front 10

ground substance

Back 10

btw cells and collagen and elastic fibers. highly hydrated gel with proteoglycans.

Front 11

proteoglycans in cartilage

Back 11

polypep chains linked with GAGs (chondrotin sulfates and keratan sulfates) bind to hyaluronic acid core.

Front 12

hyaline cartilage

Back 12

most widespread type,

Front 13

endochondral bone formation

Back 13

replacing hyaline cart model with bone

Front 14

bone vs cart

Back 14

bone presence of inorganic Ca salts in ground, makes matrix rigid, Ca reserve for body, highly vascularized, high tensile strength

Front 15

3 types of cells in bone

Back 15

osteoblast, osteocytes, osteoclasts

Front 16

osteoblasts

Back 16

produce collagen I, ground sub of bone. found at surfaces and arise from periosteum and endosteum

Front 17

osteocytes

Back 17

dervied vrom osteoblasts, cells trapped within matrix, long cytoplasmic processes canaliculi

Front 18

osteoclasts

Back 18

large mulit-nucleated cells arise from fusion of bone marrow precursors, role in bone remodeling, and resorb mineral and organic components

Front 19

periosteum

Back 19

outer surface of bone covered by fibroblast like cells.

Front 20

osteoprogenitor cell

Back 20

differentiate into osteoblast

Front 21

endosteum

Back 21

thin layer of cell

Front 22

primary component of bone

Back 22

hydroxyapatite

Front 23

primary bone

Back 23

1st bone formed by fetus, repair bone, woven or immature bone, tooth sockets, tendon insertions

Front 24

spongy bone

Back 24

cancallous bone: made up of interconnected trabeculae form mesh with marrow spaces

Front 25

compact bone

Back 25

dense bone: solid which is a result of primary to secondary, defined organization lamellae

Front 26

func unit of bone

Back 26

haversian system, formed from outward in due to deposition of bone by osteoblast which then become osteocytes. continually resorbed and remodeled

Front 27

bone formation

Back 27

intramembranous ossification and endochondral ossification

Front 28

intramembranous ossification

Back 28

skull and face, mesenchymal cells to osteoblasts, deposition of minerals within matrix turns into bone, appositional growth at outer

Front 29

endochondral ossification

Back 29

hyaline cart is replaced with bone, longitudianl growth of long bones.

Front 30

5 zones in epiphyseal plate

Back 30

resting, proliferative, hypertrophic cartilage, calcified cartilage, ossification.

Front 31

bone repair

Back 31

mesenchymal cells differentiate to chondroblasts and osteoblasts. cartilage formation and bone differentiation and cartilage matrix will be replaced with bone matrix.