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26 Cards in this Set
- Front
- Back
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CIs nitroglycerin
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Right ventricular MI
ED meds within the past 2 days |
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Argatroban,bivalirudin, and lepirudin are all anticoagulants that work how? What are the ADRs of argatroban and lepirudin, respectively.
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Direct thrombin inhibitors = they block the active site of thrombin (factor II)
argatroban is hepatotoxic lepirudin can cause fatal anaphylactic reactions |
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What are the uses for streptokinase, urokinase, and tPA?
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thrombolytics
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What is unique to tPA (alteplase) compared to other thrombolytics?
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it selectively activates plasmin that is already bound to fibrin, which is targeted to areas that have already begun to clot
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What is the approved use for clopidogrel and MOA?
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standard tx for all pts receiving stents. MI, CVA prophylaxis in pts at high risk (CAD)
ADP-mediated platelet aggregation inhibitor |
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In acidosis and alkalosis, what in the effect on Ca++?
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Acidosis - ↓binding
Alkalosis - ↑binding **when treating a pt with acidosis with bicarb, tetany may occur d/t decreased free Ca++. Its all bound up! |
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Interlukins that stimulate osteoclast activity
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IL-1 and 6
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Elevated PTH levels in malignancy. Three possibilities:
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Primary hyperparathryoidism (concurrently)
Tumor makes PTH Tumor makes PTH-like protein (x reacts with test) |
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PE tests (two) for hypocalcemia:
Chvostek's Trousseau's |
Tap facial nerve and watch face twitch
Inflate BP cuff above systolic pressure for 3 mins=carpal tunnel spasm |
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pt presents with right sided blindness, left hemiparesis, left sided hemisensory loss and language disturbance. Where is the occlusion?
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RIGHT internal carotid artery
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pt presents with acute vertigo, double vision, ataxia, facial numbness and droopy mouth. He just barfed. Where is the occlusion?
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vertebrobasilar aa
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pt presents with right weakness + facial weakness, and right hemianopsia. What structure is he hemorrhaging into?
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LEFT putamen
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Pt presents with right hemiparesis, sensory changes, and loss of left or right visual field. Where is the bleed?
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Left thalamus
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pt arrives in coma, he has small reactive pupils and before he presented he could not move any of his limbs. Where is the bleed?
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PONS
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Damage to this ganglion would impair the parotid gland and also which nucleus
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otic
inferior salivary nucleus or snip CN 9 |
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Wilson's disease deposits Cu+ in what area of the brain to produce tremor, spasticity, chorea, and weird bx
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lentiform nucleus
putamen and globus pallidus |
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Part of the thalamus that is apart of the limbic system
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anterior thalamus
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Damage to which part of the medulla produces ipsilateral loss of taste
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nucleus solitarius
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Damage to which part of the medulla produces Horner's syndrome?
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reticular formation
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Damage to which part of the medulla causes hoarse voice and gag reflex
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nucleus ambiguus
(is that a chick or a dude?! I can't tell by looking at it, but its got a hoarse voice, kinda ambiguus) |
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What are the dermatomes for the followings:
skull thumb nipple belly button big toe penis anus Knee jerk reflex ankle jerk reflex |
skull - C2
thumb - C6 nipple - T5 belly button - T10 big toe - L4 penis - S3 anus - S5 Knee jerk reflex - L4 ankle jerk reflex - S1 |
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How to calculate total peripheral resistance:
1. calculate the mean blood pressure Paverage = Pdiastolic + 1/3 (Psystolic-Pdiastolic) 2. TPR = mean blood pressure/cardiac output 3. BOOM |
Do a couple of practice runs
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How to calculate cardiac output:
1st cardiac output = systemic blood flow = pulmonary blood flow Ficks principle says pulmonary flow = O2 uptake/ (a-v O2 difference) Example arterial O2 = 20 ml O2/100ml blood = 0.2 venous O2 = 15 ml O2/ 100ml = 0.15 O2 uptake = 250 ml/min CO = 250/ (.20-.15)= 5,000 ml/min |
Yup
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Calculating renal clearance:
Clearance of substance X: clearence x [X]plasma = urine flow x [X]urine |
plug and chug
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How to calculate diffusion capacity of the lung:
DL = flow/alvelor pp |
k
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Damage to which part of the medulla causes contralateral body pain and temp loss?
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spinothalamic tract
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