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116 Cards in this Set
- Front
- Back
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acetaminophen (tx)
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N-acetylcystein
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salicylates (tx)
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NaHCO3 alkalinize urine dialysis
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amphetamines (tx)
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NH4Cl acidify urine
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anticholesterases organophophates (tx)
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atropine pralidoxime
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antimsucarinic anticholnergic (tx)
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physotstigine salicylate
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BB (tx)
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glucagon
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digitalis (tx)
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stop digitalis, normalize K, lidocaine, anti-dig Fab frags Mg
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iron (tx)
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deferoxamine
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lead (tx)
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CaEDTA, dimercaprol succimer penicillamine
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mercury, arsenic gold (tx)
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dimercaprol (BAL), succimer
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copper arsenic gold (tx)
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penicillamine
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cyanide (tx)
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nitrite hydroxocobalamin thixsulfate
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methemoglobine (tx)
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methylene blue and vit C
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carbone monoxide (tx)
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O2
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methanol ethylene glycol (tx)
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ehtanol dialsis fomepizole
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opiods (tx)
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naloxone/naltrexone
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benzos (tx)
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flumazenil
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TCAs (tx)
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NaHco3 serum alk
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heparin (tx)
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protamine sulfate
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warfain (tx)
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vitk FFP
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theophylline (tx)
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BB
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tPA, streptokinase (tx)
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aminocaproic acid
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atoprine like (SE)
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TCAs, clopromazine, typical neurlep, histamines, promehtazine
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coronary vasoaspm (SE)
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cocain (VC) sumatriptan VC methamphetamines ergots (VC)
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cutaneous flusing (SE)
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VANC vancomycin, adenosin, niacin, CCB
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dilated CM (SE)
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doxorubin daunorubicin
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torsades (SE)
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class 3 (satolol), class 1A (quinidine), eisarpide ;
tx: Mg |
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agranulocytosis (SE)
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clozapine carbamazepine, colchic9ne PTU, methimazole dapsone
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aplstic anemia (SE)
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chlormaphenicol, benzene, NSAIDs, PTU, ethmiazole
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direct coombs hemolytic anemia(SE)
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methyldopa
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gray baby syndrome
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chloramphenicol
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hemolysis in G6PD def patients
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IS PAIN
isoniazid, sulf, primaquine, high aspirin, ibuprofen, nitrofuantoin; dasone naphtaline |
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megalobasltic anemia (SE)
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having a blast w/ PMS
phenytoin methotrexate sulfa drugs |
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thormbotic complicatiosn (SE)
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OCPs E/P do not use in smokers >35 okay w/ HRP
no w/ migraine w/ aura |
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pulmonary fibrosis (SE)
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bleomycin amiodarone busulfan
hard to BLAB w/ pulm fibrosis |
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acute cholestatic hepatitis (SE)
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macrolides erythromycin
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focal to massive hepatic necrosis (SE)
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halothan valproic acid acetmainophen
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hepatitis (SE)
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INH
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psedumembrnaous colitis (SE)
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clindamycin ampicillin
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adrenocortial insuff (SE)
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glucocorticoid withdrawel HPA suppression
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gynecomastia (SE)
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some drugs create awesome knockers
spironolactone, digitalis, cimetidine, alcohol, estrogens ketoconazole; marijauna |
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hot flashes (SE)
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tamoxifen clomiphene SERMs
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hyothyroidsm (SE)
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lithium amiodarone
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P450 inducers
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PQRS BCG
phenytoin, quinidine, rifampin, st john's wart, barb, carbamazepine, griseoflavin |
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P450 inhibitors
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KEG SIC from acute alochol
ketoconazole, erythromycin, grapefruit, sulfonamides, isoniazid, cimetidine |
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glycolysis (RLS)
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PFK-1
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gluconeogensis (RLS)
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F16BP
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glycogneolysis (RLS)
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glycogen phosphorylase
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glycogenesis (RLS)
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glycogen synthase
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ketogenesis (RLS)
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HMG-COA synthase
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CH synthesis (RLS)
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HMG-COA reductase
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TCA cycle (RLS)
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isocitrate DH
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HMP shunt (RLS)
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G6PD
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pyramidine sythesis (RLS)
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CPS2 (cytosol from glutamine nitrogen)
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purine synthesis (RLS)
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PRPP amidotransferase
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urea cycle (RLS)
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CPS1 in mitochondria N from ammonium
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FA oxidation (B ox) (RLS)
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CAT1 (inhib by malonyl CoA)
carnitine acyltransferase 1 |
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FA synthesis (RLS)
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ACC acetyl CoA carboxylase
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lipolysis (RLS)
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hormone sensitive lipase
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heme synthesis (RLS)
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ALA synthase
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cytosol biochem places
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glycolysis PPP and FA synthesis
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mitochondria only biochem places
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CAC, ketognesis, B oxidaiton
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both mitochondria and cytosol biochem places
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urea cycle and gluconeognesis
RBC heme syntehsis |
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sulfa allergies drugs
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celacoxib, iduretics (furosimide acetazolamide, thiazide), probeencid, TMP/SMX, sulfasalazine, sumatriptan (sorta)
causes fever rash poss SJSJ hemolytic anemia TP agranulocytosis urticaria hives photsn |
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2 narrow spectrum drugs for anaerobes
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clindamycin metronidazole
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drugs causing ototoxicity and neprotoxicity
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aminlygocides, vancomycin diretics ciplastin
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gray man syndrome
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amioderone
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red man sy ndroem
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vanco
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gray baby syndrome
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chloramphenicol
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photosensitvity drugs
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amioderone sulfonamides tetracyclines
SAT for a photo |
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SJS drugs
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ehtosuxaide maidridine, sulfa, lamotrigine, carbamaziepine, phenobarbital pheytoin PCN allopurinol
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disulfiram reaction drugs
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antabuse inhib aldehyde DH
metronidazole cephalosporins sufonureas procarbazine vanco/linezolide |
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lupus causing drugs
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hydrazoline sufla phenytoin isoniazid procainide
it's not HIPPS to have lupus |
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drugs to avoid in preg
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SAFE Moms Take Really Good Care
sulfonamides (kernicterus) aminoglycodies (oto), fluoquinolone (cartilage) metrodizole 9mutagenesis) tetraycline (disclored teeth and bone) ribavirn (teraatrogenic) griseofulvin (terato) chloramphenical (gray baby) |
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ginigival hyperplasia drugs
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pheytoin
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gout drugs
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corticosteroids heparin
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osteoporosis drugs
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corticosteroids and heparin give bisphos to treat
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tendonitis, tendon ruptur and cartilage damage in kids DRUG
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fluorquinolones
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fanconi's syndrome drugs
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expired tetracycline heavy metal exposure
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drugs causing interstitial nephritis
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methicillin NSAIDs, furosemide
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drugs causing hemorrhagic cystitis
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cyclophosphamide, ifosfamide (give MESNA)
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drugs causing cinchonism
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dizzy HA vision tinnitis
quinididne quinine |
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drugs causing diabetes insipidus
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lithium democlocycline
treat w/ HCT |
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drugs causing parkinson like syndorme
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haloperidol, chlorpormazine, reserpine, metoclopramide
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drugs causing seizure
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buprioopion (dec threshold) imipenem/cilastin, meropenaum IZD, n flurane (gen anethestic), primrose oil ; benzo/alcohol withdrawl
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drugs causing tardive dyskinesia
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antipsychotics
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drugs cuasing nephrotox/neurotox
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polymyxins
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drugs causing
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MetHb: CQ, PQ, dapson, sulfonimides, lidocaine, metoclopromide, nitroglycerine (nitro)
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ACEi teratogenic
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renal damage (in mom prevents proteinuria)
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fetal alcohol syndrome teratogenic
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newborns inc congeital abnormalities pre/post dev retardation microcephaly homoproscencephaly facial abnormlaities limib dislocation heart/lung fistuals
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teratogenic alkylating agents
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absence of digits multple amalies
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teratogenic coacin
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abnormalal fetal dev/addiction insuff bf spont abortion IUGR
placental abruptions (hypoai to fetus) abrutio placentae |
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teratogenic valproate
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folate antag, neural tube defects
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teratogenic iodide
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congeital goiter or hypothyroidism
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teratogenic lithium
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bipolar mom ebstein's anomaly---tricuspid valve dipalced TR/TS into RV so hypopolastic
ASD inc RA inc risk SVt and WPW wie split S2 |
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teratogenic maternal diabetes
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transposition of arch, hypoglycmeia, large (LGA-erb ducenne, shoulder dystocial clavical fracture long labor); caudal regression syndrome (mermaid) flaccid paralysis anal atresia and sirenomelia
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teratogenic smoking
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preterm labor IUGR ADHD
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teratogenic thalidomide
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limb defects flipper
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valproate teratogen
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no folate absorption
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vit A excess teratogen
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spont abortions and birth defects cleft palate cardiac abnormalites
ACCUTANE |
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warfarin teratogen
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bone deformities fetal hemorrhage abortion
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pneumonic for capsules in bact
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some killers have nice shiny bodies
strep pneumo klebsiella HIb conjugated w/ diptheria toxin DTP neisseria menigntis salmonella GBS quellung reaction swells prevents phagocytosis |
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apo A 1
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activates LCAT esterfies tissue Ch picked up by HDL (a1 on your lCAT)
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apo C2
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activates CLL releases FAs and glycerol from CM VLDL and IDL
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apo C3
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inhib CLL
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apo B48
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CM fro intestinal mucosa into the lymphatics to peripheral circultion
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apo B100
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binds LDL Rc to tissues secretion assemly of VLDL IDL LDL in liver
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apo E
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extra remant uptak eo fCM and IDL y liver
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tryptophan makes what NT?
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niacin (need B6); serotonic (needs BH4 dihydropterin reductase)
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phenyalanine makes what NT?
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melatonin tyrosine
dopa, Nor EPi |
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histidine makes what?
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histimine (B6)
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glyciene is needed in what pathway?
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heme (ALA synthase) +B6 to porphyrin and heme
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gutamate makes what?
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B6 and GABA and glutathione?
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PK deficiency
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AR in glycolytic dec ATP damages cell membrane loss of water to dehydrated and speculted
damaged RBCs mac destrcution in sleep inc 2, 3BPG hemolytic anemia work hypertorphy of the spleen and juandice at birth but MILD right shift |
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pyruvated DH
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AR inc pyruvate w/ alanine via transamination
dc acetyl coA dec ATP inc LA, enurologic myopathy fatal early intake nutrients w/ acetyl coA fats ketogenic AA lycine and leucine |
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alport's syndrome
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T4 collagen split BM nerve disorders ocular disorders XD
can't see can't pee can't hear |
