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229 Cards in this Set

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hives and
angioedema
anaphylactic rxn
treat anaphylactic with
1-epi
2-steroids
3-antihistamines
amyloidsosis
plasma cells
multiple myeloma
amyloidosis
primary amyloidosis
TB
rheumatoid arthritis
familial med fever
secondary amyloidosis
amyloid builds up in
spleen
liver
kidney
adrenal glands
LN
secondary amyloidosis
affect nerves/organs
hereditary amyloidosis
deposits of amyloid
alzheimer's dx
diabetes mellitus type 2
amyloid in diabetes
diabetes mellitus
aschoff body
rheumatic fever
most common damaged valve
mitral
focal interstitial myocardial inflammation
aschoff body
jones criteria
rheumatic fever
carditis
arthritis
chorea
erythema marginatum
subcutaneous nodules
major criteria
rheumatic fever
fever
arthralgias
history
EKG
lab test
minor criteria
rheumatic fever
may follow strept infection
rheumatic fever
not an infection
rheumatic fever
heterophil test
infectious mononucleosis
infectious mononucleosis
viral infection
CMV
EBV
mono
lymphocytosis
atypical lymphocytes
positive heterophile test
rheumatic fever
screen mono
heterophile
no antiviral therapy
mono
burkitt lymphoma
nasopharyngeal carcinoma
hairy leukoplakia
EBV
large amts of protein in CSF
multiple sclerosis
eaton lambert
like myasthenia gravis
inadequate release of
acetylcholine
eaton lambert
improves with rest
myasthenia gravis
attach ACh receptors on muscle side of NMJ
myasthenia gravis
myasthenia gravis a/w
thyrotoxicosis
RA
SLE
outer layer of adrenal gland
addison
partial/ complete
failure of adenocortical
addison
treat addison
cortisol
hemorrhagic necrosis of adrenal cortex
waterhouse-friderichsen
waterhouse-friderichsen a/w
meningococcal meningitis
heberden's nodes
bony swellings
DIP joints
osteroarthritis a/w
heberden's nodes
proximal interphalangeal joint
bouchard's node
most common arthritis
osteoarthritis
morpho changes of osteorthritis
eburnation of bone
oteophyte formation
ivory appearance of bone
eburnation of bone
otephyte formation
bony spur formation
joint mice
osteoarthritis
chronic inflammation that cause articular cartilage to degenerate
ostoarthritis
osteoarthritis mostly affects
intervertebral joint
phalangeal joint
knee
hips
woman
after 50
osteoarthritis
most common pancreatic endocrine disorder
diabetes
polydipsia
polyuria
polyphagia
triad of diabetes
attack on body by immune cells
RA
still's dx
type of RA that occurs in young people
proliferative inflammation of synovial membrane
RA
osteophyte
osteoarthritis
collagen dx
1-RA
2-SLE
3-polyarteritis nodosa
4-dermatomyositis
5-scleroderma
inflammatory damage to CT & BV
collagen dx
deposition of fibrinoid material
collagen dx
increase in immune cell
histiocye
monocyte
macrophage
dendritic
mandible
males 20
benign
oral lesion
eosinophilic granulom
infants
skin rash
anemia
hemorrhage
no oral lesion
lettere-siwe
5
triad:
1-exophthalmos
2-diabetes insipidus
3-bone destruction
TXT:radiation
hand
schuller
christian dx
uterica
fever
lymphadenopathy
edema
arthritis
serum sickness
autoimmune dx
SLE
inflammation of joints
tendons
CT
SLE
second most common autoimmune
rheumatic disorder
sjogren
chronic
systemic
inflammatory dx
peripheral joints
RA
BV dx
polyarteritis nodosa
BV attacked by immune cells
polyarteritis nodosa
immune complex dx
type III hypersensitivity rxn
doesnt have a role in type 3 hypersensitivity rxn
histamine
type 2 hypersensitivity
cytotoxic
antigens combine with
IgE on mast/basophil
type I hypersensitivity
antigen antibody rxn
type I hypersensitivity
cause release of vasoactive
inflammatory mediators
type I
cytotoxic rxn
t
type 2
antigen-antibody activate cytoxic cells (killer T, macrophages)
type 2
cell mediated cytotoxicity
type 2
involves complement
type 2
immune complex
type 3
immune complex activate
complement
acute inflammation
type 3
cellular
cell mediated
delayed
tuberculin type
type 4
sensitized T lymphocytes
type 4
circulating antibodies
NOT involved
type 4
adenoma
primary hyperparathyroidism
hypocalcemia of chronic renal dx
secondary hyperparathyroidism
thyroidectomy
HYPOparathyroidism
defective end-organ responsiveness to PTH
PSEUDOparathyroidism
hyperthyroidism persists after definitive therapy for secondary hyperparathyroidism
tertiary hyperparathyroidism
rare
HYPOparathyroidism a/w congenital thymic hypoplasia
digeorge
manifestations of
hyperparathyroidism
osteoporosis
giant cell granulomas
metastatic calcifications
certain drugs may induce
SLE
what is common cause of death of SLE
renal failure
a/w SLE
raynaud
acrocyanosis
raynaud
specific for SLE
anti-DNA
anti -Sm antibodies
stiffness in
muscles of
neck
shoulders
hip
polymyalgia rheumatica
medium sized arteries are inflamme >
reduce blood supply to organs
polyarteritis
nodosa
chronic inflammatory of large arteries
temporal
inflammation of joints
inflmmation of conjunctica
reiter's syndrome
CT disease
inflammation of spine
large joints
ankylosing spondylitis
chronic
relapsing
painful mouth sores
bechets
pus like fluid in anterior chamber of eye
bechets
increased melanin
addison
jaundice >
hemolytic anemia
biliary obstruction
hepatocellular dx
derived from ferritin
hemosiderin
witin macrophages of
bone marrow
liver
spleen
hemosiderin
a/w thalassemia major
hemodiderosis
doesnt cause tissue/organ damage
hemosiderosis
bronze dx
hemochromatosis
tissue and organ damage
hemochromatosis
inherited disorder of
purine metabolism
gout
gout >
kidney stones
painful arthritis caused by deposits of Ca pyrophosphate crystals
pseudogout
bile =
bile salts
lecithin
cholesterol
gallstones in gallbladder =
cholelithiasis
gallstones in bile ducts
choledocholithiasis
strawberry gallbladder
cholesterolosis
gallstones block common bile duct >
OBSTRUCTIVE JAUNDICE
hypothyroidism =
myxedema
dental findings in hypothyroidism
underdev mandible
overdev maxilla
delayed eruption of teeth
deciduous teeth remain longer
thyroid disorders may result from
thyroid
pituitary
hypothalamus
sign of kidney dx
proteinuria
alcohol intoxication
ketouria
uncontrolled diabetes
ketouria
lethal head injury
subdural hematoma
bridging veins
subdural
fluctuating levels of consciousness/com
subdural
dizziness
cold perspiration
visual prob
loss of consciousness
concussion
recover compleely within hrs/say
concussion
intracranial tumor
meningioma
infarction of cerebrum
cerebral infarction
arterial occlusion by
thrombus
embolus
cerebral infarction
sudden paralysis on one side of body
cerebral infarction
numbness on one side of body
cerebral infarction
neurologic dysfxn
vit E
tendency to hemorrhage
vit K
antioxidant
vit E
def of vit E
neurologic dysfxn
clot blood
vit k
body growth
of specialized tissue:
especially retina
vit A
rhodopsin
vit A
85% Hyperthyroidism
graves
2 types of hyperthyroidism
graves
plummers
toxic nodular goiter
plummer
no protruding eyes
plummer
female
60
longstanding simple goiter
plummer
autoimmune
woman 20-40
graves
following an infection/physical emotional stress

anxiety
EXOPHTHALMOS
GRAVES
calcification in
degenerated necrotic tissu
dystrophic calcification
metastatic
pathologic
eggshell
types of calcifications
nonosseous
viable tissue
metastatic calcification
in stomach
lung
kidney

secrete acid
metastatic calcification
metastatic occurs
hyperparathyroidism
hypervit D
occurs in
excretory
secretory
pathologic calcification
bone
teeth
pathologic
intrathoracic LN
eggshell
calcifications underskin
calcinosis
a/w scleroderma
calcinosis
kidney stones =
calculi in kidney
pellagra
vit B3
glossitis
B2
megaloblastic anemia
B12
folic acid
cobalamin
b12
pyridoxine
B5
neurologic dysfxn
B12
defective formation of mesenchymal tissue
vit c
cheilosis
glossitis
B 2
B6
wet beriberi
dry beriberi
B1
preventable blindness
trachoma
trachoma caused
chlamydia trachomatis
newborns
inclusion conjunctivitis
pink eye >
HEMOPHILUS
AEGYPTIUS
long standing dryness of eye
keratoconjunctivitis sicca
dry symtom in
RA
SLE
sjogren
def of enzyme
hexosaminidase A
tay sach
inborn errors in lipid metabolism
lipid storage disease
accumulation of ganglioside
tay sach
accumulation of sphingomyelin
neimann pick
accumulation of sphingomyelin in
brain
spleen
liver
painful
accumulation of glycolipid
fabry
def of
alpha galactosidase
fabry
accumulation of
glucosylceramide
gaucher
def of enzyme
glucocerebrosidase
gaucher
elevated in acute pancreatitis
lipase
amylase
diagnosis of acute pancreatitis
type of pain
detecting elevated lipase/amylase in serum/urine
sever knife like
upper pain
acute pancreatitis
hashimoto
autoimmune
cause of hypothyroidisim is
hashimoto
rxn of immune system against thyroid
hashimoto
production of antibodies in response to
thyroid antigen
in hashimoto see
replacement of thyroid with
lymphocytes
lymphoid germinal centers
excessive amt of GH >
acromegaly
iris
target lesion
erythema multiforme
acute self limited eruption
erythema multiforme
type of hypersensitivity
EM
EM in occurs in response to
meds
infections
illness
lesions aw mucous membrane
steven johnson
multiple large blisters
toxic epidermal necrolysis
impetigo
invasion of epi by
staph
strep
similar to cellulitis but more superficial
impetigo
contagious
impetigo
txt impetigo
-erythromycin
-dicloxacillin
renal disease of kids
acute glomerulonephritis
peptic ulcers in
duodenum
circumscribed lesion in mucosal membrane
peptic ulcer
in lower esoph
stomach
pylorus
duod
jejunum
peptic ulcer
stomach mucosa
gastric ulcer
repeated regurgitation of HCL
esophageal ulcer
erosion of lining of duodenum
duod ulcer
type of peptic ulcer
imbalance btw
acid/pepsin secretion
duod ulcer
precipitated inflammation by
aspirin
NSAID
duod ulcer
common complication of peptic ulcer
hemorrhage
common symptom of peptic ulcer is
pain
perforation
peptic ulcer
perforation can lead to
acute peritonitis > death
damage to hypothalamus
diabetes insipidus
lack of ADH
diabetes insipidus
nuclei of hypothalamus
ADH
secreted by post pit
ADH
defefect of kidney tubules with
passage of lot of urine
nephrogenic insipidus
partial /complete failure of receptors located on tubules
nephrogenic insipidus
very large amt of dilute urine
NI
damage to supraoptic nuclei
diabetes insipidus
allergic asthma
most common
severe episode of asthma
status asthmaticus
treat acute astmatic attack
beta 2 agonist
beta 2 agonist
terbutaline
albuterol
nitrous oxide safe for
asthma
indicated for asthmatics triggered by anxiety
nitrous oxide
provokes asthma
aspirin
NSAIDS