Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
229 Cards in this Set
- Front
- Back
|
hives and
angioedema |
anaphylactic rxn
|
|
|
treat anaphylactic with
|
1-epi
2-steroids 3-antihistamines |
|
|
amyloidsosis
|
plasma cells
|
|
|
multiple myeloma
amyloidosis |
primary amyloidosis
|
|
|
TB
rheumatoid arthritis familial med fever |
secondary amyloidosis
|
|
|
amyloid builds up in
spleen liver kidney adrenal glands LN |
secondary amyloidosis
|
|
|
affect nerves/organs
|
hereditary amyloidosis
|
|
|
deposits of amyloid
|
alzheimer's dx
diabetes mellitus type 2 |
|
|
amyloid in diabetes
|
diabetes mellitus
|
|
|
aschoff body
|
rheumatic fever
|
|
|
most common damaged valve
|
mitral
|
|
|
focal interstitial myocardial inflammation
|
aschoff body
|
|
|
jones criteria
|
rheumatic fever
|
|
|
carditis
arthritis chorea erythema marginatum subcutaneous nodules |
major criteria
rheumatic fever |
|
|
fever
arthralgias history EKG lab test |
minor criteria
rheumatic fever |
|
|
may follow strept infection
|
rheumatic fever
|
|
|
not an infection
|
rheumatic fever
|
|
|
heterophil test
|
infectious mononucleosis
|
|
|
infectious mononucleosis
|
viral infection
|
|
|
CMV
EBV |
mono
|
|
|
lymphocytosis
atypical lymphocytes positive heterophile test |
rheumatic fever
|
|
|
screen mono
|
heterophile
|
|
|
no antiviral therapy
|
mono
|
|
|
burkitt lymphoma
nasopharyngeal carcinoma hairy leukoplakia |
EBV
|
|
|
large amts of protein in CSF
|
multiple sclerosis
|
|
|
eaton lambert
|
like myasthenia gravis
|
|
|
inadequate release of
acetylcholine |
eaton lambert
|
|
|
improves with rest
|
myasthenia gravis
|
|
|
attach ACh receptors on muscle side of NMJ
|
myasthenia gravis
|
|
|
myasthenia gravis a/w
|
thyrotoxicosis
RA SLE |
|
|
outer layer of adrenal gland
|
addison
|
|
|
partial/ complete
failure of adenocortical |
addison
|
|
|
treat addison
|
cortisol
|
|
|
hemorrhagic necrosis of adrenal cortex
|
waterhouse-friderichsen
|
|
|
waterhouse-friderichsen a/w
|
meningococcal meningitis
|
|
|
heberden's nodes
|
bony swellings
DIP joints |
|
|
osteroarthritis a/w
|
heberden's nodes
|
|
|
proximal interphalangeal joint
|
bouchard's node
|
|
|
most common arthritis
|
osteoarthritis
|
|
|
morpho changes of osteorthritis
|
eburnation of bone
oteophyte formation |
|
|
ivory appearance of bone
|
eburnation of bone
|
|
|
otephyte formation
|
bony spur formation
|
|
|
joint mice
|
osteoarthritis
|
|
|
chronic inflammation that cause articular cartilage to degenerate
|
ostoarthritis
|
|
|
osteoarthritis mostly affects
|
intervertebral joint
phalangeal joint knee hips |
|
|
woman
after 50 |
osteoarthritis
|
|
|
most common pancreatic endocrine disorder
|
diabetes
|
|
|
polydipsia
polyuria polyphagia |
triad of diabetes
|
|
|
attack on body by immune cells
|
RA
|
|
|
still's dx
|
type of RA that occurs in young people
|
|
|
proliferative inflammation of synovial membrane
|
RA
|
|
|
osteophyte
|
osteoarthritis
|
|
|
collagen dx
|
1-RA
2-SLE 3-polyarteritis nodosa 4-dermatomyositis 5-scleroderma |
|
|
inflammatory damage to CT & BV
|
collagen dx
|
|
|
deposition of fibrinoid material
|
collagen dx
|
|
|
increase in immune cell
histiocye |
monocyte
macrophage dendritic |
|
|
mandible
males 20 benign oral lesion |
eosinophilic granulom
|
|
|
infants
skin rash anemia hemorrhage no oral lesion |
lettere-siwe
|
|
|
5
triad: 1-exophthalmos 2-diabetes insipidus 3-bone destruction TXT:radiation |
hand
schuller christian dx |
|
|
uterica
fever lymphadenopathy edema arthritis |
serum sickness
|
|
|
autoimmune dx
|
SLE
|
|
|
inflammation of joints
tendons CT |
SLE
|
|
|
second most common autoimmune
rheumatic disorder |
sjogren
|
|
|
chronic
systemic inflammatory dx peripheral joints |
RA
|
|
|
BV dx
|
polyarteritis nodosa
|
|
|
BV attacked by immune cells
|
polyarteritis nodosa
|
|
|
immune complex dx
|
type III hypersensitivity rxn
|
|
|
doesnt have a role in type 3 hypersensitivity rxn
|
histamine
|
|
|
type 2 hypersensitivity
|
cytotoxic
|
|
|
antigens combine with
IgE on mast/basophil |
type I hypersensitivity
|
|
|
antigen antibody rxn
|
type I hypersensitivity
|
|
|
cause release of vasoactive
inflammatory mediators |
type I
|
|
|
cytotoxic rxn
t |
type 2
|
|
|
antigen-antibody activate cytoxic cells (killer T, macrophages)
|
type 2
|
|
|
cell mediated cytotoxicity
|
type 2
|
|
|
involves complement
|
type 2
|
|
|
immune complex
|
type 3
|
|
|
immune complex activate
|
complement
|
|
|
acute inflammation
|
type 3
|
|
|
cellular
cell mediated delayed tuberculin type |
type 4
|
|
|
sensitized T lymphocytes
|
type 4
|
|
|
circulating antibodies
NOT involved |
type 4
|
|
|
adenoma
|
primary hyperparathyroidism
|
|
|
hypocalcemia of chronic renal dx
|
secondary hyperparathyroidism
|
|
|
thyroidectomy
|
HYPOparathyroidism
|
|
|
defective end-organ responsiveness to PTH
|
PSEUDOparathyroidism
|
|
|
hyperthyroidism persists after definitive therapy for secondary hyperparathyroidism
|
tertiary hyperparathyroidism
|
|
|
rare
HYPOparathyroidism a/w congenital thymic hypoplasia |
digeorge
|
|
|
manifestations of
hyperparathyroidism |
osteoporosis
giant cell granulomas metastatic calcifications |
|
|
certain drugs may induce
|
SLE
|
|
|
what is common cause of death of SLE
|
renal failure
|
|
|
a/w SLE
|
raynaud
|
|
|
acrocyanosis
|
raynaud
|
|
|
specific for SLE
|
anti-DNA
anti -Sm antibodies |
|
|
stiffness in
muscles of neck shoulders hip |
polymyalgia rheumatica
|
|
|
medium sized arteries are inflamme >
reduce blood supply to organs |
polyarteritis
nodosa |
|
|
chronic inflammatory of large arteries
|
temporal
|
|
|
inflammation of joints
inflmmation of conjunctica |
reiter's syndrome
|
|
|
CT disease
inflammation of spine large joints |
ankylosing spondylitis
|
|
|
chronic
relapsing painful mouth sores |
bechets
|
|
|
pus like fluid in anterior chamber of eye
|
bechets
|
|
|
increased melanin
|
addison
|
|
|
jaundice >
|
hemolytic anemia
biliary obstruction hepatocellular dx |
|
|
derived from ferritin
|
hemosiderin
|
|
|
witin macrophages of
bone marrow liver spleen |
hemosiderin
|
|
|
a/w thalassemia major
|
hemodiderosis
|
|
|
doesnt cause tissue/organ damage
|
hemosiderosis
|
|
|
bronze dx
|
hemochromatosis
|
|
|
tissue and organ damage
|
hemochromatosis
|
|
|
inherited disorder of
purine metabolism |
gout
|
|
|
gout >
|
kidney stones
|
|
|
painful arthritis caused by deposits of Ca pyrophosphate crystals
|
pseudogout
|
|
|
bile =
|
bile salts
lecithin cholesterol |
|
|
gallstones in gallbladder =
|
cholelithiasis
|
|
|
gallstones in bile ducts
|
choledocholithiasis
|
|
|
strawberry gallbladder
|
cholesterolosis
|
|
|
gallstones block common bile duct >
|
OBSTRUCTIVE JAUNDICE
|
|
|
hypothyroidism =
|
myxedema
|
|
|
dental findings in hypothyroidism
|
underdev mandible
overdev maxilla delayed eruption of teeth deciduous teeth remain longer |
|
|
thyroid disorders may result from
|
thyroid
pituitary hypothalamus |
|
|
sign of kidney dx
|
proteinuria
|
|
|
alcohol intoxication
|
ketouria
|
|
|
uncontrolled diabetes
|
ketouria
|
|
|
lethal head injury
|
subdural hematoma
|
|
|
bridging veins
|
subdural
|
|
|
fluctuating levels of consciousness/com
|
subdural
|
|
|
dizziness
cold perspiration visual prob loss of consciousness |
concussion
|
|
|
recover compleely within hrs/say
|
concussion
|
|
|
intracranial tumor
|
meningioma
|
|
|
infarction of cerebrum
|
cerebral infarction
|
|
|
arterial occlusion by
thrombus embolus |
cerebral infarction
|
|
|
sudden paralysis on one side of body
|
cerebral infarction
|
|
|
numbness on one side of body
|
cerebral infarction
|
|
|
neurologic dysfxn
|
vit E
|
|
|
tendency to hemorrhage
|
vit K
|
|
|
antioxidant
|
vit E
|
|
|
def of vit E
|
neurologic dysfxn
|
|
|
clot blood
|
vit k
|
|
|
body growth
of specialized tissue: especially retina |
vit A
|
|
|
rhodopsin
|
vit A
|
|
|
85% Hyperthyroidism
|
graves
|
|
|
2 types of hyperthyroidism
|
graves
plummers |
|
|
toxic nodular goiter
|
plummer
|
|
|
no protruding eyes
|
plummer
|
|
|
female
60 longstanding simple goiter |
plummer
|
|
|
autoimmune
woman 20-40 |
graves
|
|
|
following an infection/physical emotional stress
anxiety EXOPHTHALMOS |
GRAVES
|
|
|
calcification in
degenerated necrotic tissu |
dystrophic calcification
|
|
|
metastatic
pathologic eggshell |
types of calcifications
|
|
|
nonosseous
viable tissue |
metastatic calcification
|
|
|
in stomach
lung kidney secrete acid |
metastatic calcification
|
|
|
metastatic occurs
|
hyperparathyroidism
hypervit D |
|
|
occurs in
excretory secretory |
pathologic calcification
|
|
|
bone
teeth |
pathologic
|
|
|
intrathoracic LN
|
eggshell
|
|
|
calcifications underskin
|
calcinosis
|
|
|
a/w scleroderma
|
calcinosis
|
|
|
kidney stones =
|
calculi in kidney
|
|
|
pellagra
|
vit B3
|
|
|
glossitis
|
B2
|
|
|
megaloblastic anemia
|
B12
folic acid |
|
|
cobalamin
|
b12
|
|
|
pyridoxine
|
B5
|
|
|
neurologic dysfxn
|
B12
|
|
|
defective formation of mesenchymal tissue
|
vit c
|
|
|
cheilosis
glossitis |
B 2
B6 |
|
|
wet beriberi
dry beriberi |
B1
|
|
|
preventable blindness
|
trachoma
|
|
|
trachoma caused
|
chlamydia trachomatis
|
|
|
newborns
|
inclusion conjunctivitis
|
|
|
pink eye >
|
HEMOPHILUS
AEGYPTIUS |
|
|
long standing dryness of eye
|
keratoconjunctivitis sicca
|
|
|
dry symtom in
|
RA
SLE sjogren |
|
|
def of enzyme
hexosaminidase A |
tay sach
|
|
|
inborn errors in lipid metabolism
|
lipid storage disease
|
|
|
accumulation of ganglioside
|
tay sach
|
|
|
accumulation of sphingomyelin
|
neimann pick
|
|
|
accumulation of sphingomyelin in
|
brain
spleen liver |
|
|
painful
accumulation of glycolipid |
fabry
|
|
|
def of
alpha galactosidase |
fabry
|
|
|
accumulation of
glucosylceramide |
gaucher
|
|
|
def of enzyme
glucocerebrosidase |
gaucher
|
|
|
elevated in acute pancreatitis
|
lipase
amylase |
|
|
diagnosis of acute pancreatitis
|
type of pain
detecting elevated lipase/amylase in serum/urine |
|
|
sever knife like
upper pain |
acute pancreatitis
|
|
|
hashimoto
|
autoimmune
|
|
|
cause of hypothyroidisim is
|
hashimoto
|
|
|
rxn of immune system against thyroid
|
hashimoto
|
|
|
production of antibodies in response to
|
thyroid antigen
|
|
|
in hashimoto see
replacement of thyroid with |
lymphocytes
lymphoid germinal centers |
|
|
excessive amt of GH >
|
acromegaly
|
|
|
iris
target lesion |
erythema multiforme
|
|
|
acute self limited eruption
|
erythema multiforme
|
|
|
type of hypersensitivity
|
EM
|
|
|
EM in occurs in response to
|
meds
infections illness |
|
|
lesions aw mucous membrane
|
steven johnson
|
|
|
multiple large blisters
|
toxic epidermal necrolysis
|
|
|
impetigo
|
invasion of epi by
staph strep |
|
|
similar to cellulitis but more superficial
|
impetigo
|
|
|
contagious
|
impetigo
|
|
|
txt impetigo
|
-erythromycin
-dicloxacillin |
|
|
renal disease of kids
|
acute glomerulonephritis
|
|
|
peptic ulcers in
|
duodenum
|
|
|
circumscribed lesion in mucosal membrane
|
peptic ulcer
|
|
|
in lower esoph
stomach pylorus duod jejunum |
peptic ulcer
|
|
|
stomach mucosa
|
gastric ulcer
|
|
|
repeated regurgitation of HCL
|
esophageal ulcer
|
|
|
erosion of lining of duodenum
|
duod ulcer
|
|
|
type of peptic ulcer
imbalance btw acid/pepsin secretion |
duod ulcer
|
|
|
precipitated inflammation by
aspirin NSAID |
duod ulcer
|
|
|
common complication of peptic ulcer
|
hemorrhage
|
|
|
common symptom of peptic ulcer is
|
pain
|
|
|
perforation
|
peptic ulcer
|
|
|
perforation can lead to
|
acute peritonitis > death
|
|
|
damage to hypothalamus
|
diabetes insipidus
|
|
|
lack of ADH
|
diabetes insipidus
|
|
|
nuclei of hypothalamus
|
ADH
|
|
|
secreted by post pit
|
ADH
|
|
|
defefect of kidney tubules with
passage of lot of urine |
nephrogenic insipidus
|
|
|
partial /complete failure of receptors located on tubules
|
nephrogenic insipidus
|
|
|
very large amt of dilute urine
|
NI
|
|
|
damage to supraoptic nuclei
|
diabetes insipidus
|
|
|
allergic asthma
|
most common
|
|
|
severe episode of asthma
|
status asthmaticus
|
|
|
treat acute astmatic attack
|
beta 2 agonist
|
|
|
beta 2 agonist
|
terbutaline
albuterol |
|
|
nitrous oxide safe for
|
asthma
|
|
|
indicated for asthmatics triggered by anxiety
|
nitrous oxide
|
|
|
provokes asthma
|
aspirin
NSAIDS |
