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96 Cards in this Set
- Front
- Back
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Specific Antidote to Acetaminophen?
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N-acetylcysteine
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Specific Antidote to Salicylates?
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NaHCO3 (alkalinize urine)
Dialysis |
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Specific Antidote to Amphetamines (basic)?
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NH4Cl (acidify urine)
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Specific Antidote to Anticholinesterases and organophosphates?
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Atropine
Pralidoxime |
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Specific Antidote to Antimuscarinic, anitcholinergic agents?
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Physostigmine salicylate
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Specific Antidote to Beta Blockers?
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Glucagon
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Specific Antidote to Digitalis?
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Stop dig
Normalize K+ Lidocaine Anti-dig Fab fragments Mg2+ |
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Specific Antidote to Iron?
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Deferoxamine
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Specific Antidote to Lead?
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CaEDTA
Dimercaprol Succimer Penicillamine |
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Specific Antidote to Mercury, Arsenic, or Gold?
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Dimercaprol (BAL)
Succimer |
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Specific Antidote to Copper, Arsenic, or Gold?
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Penicillamine
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Specific Antidote to Cyanide?
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Nitrite
Hydroxocobalamin Thiosulfate |
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Specific Antidote to Methemoglobin?
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Methylene blue
Vitamin C |
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Specific Antidote to Carbon Monoxide?
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100% O2
Hyperbaric O2 |
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Specific Antidote to Methanol or Ethylene Glycol
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Ethanol
Dialysis Fomepizole |
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Specific Antidote to Opioids?
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Naloxone/Naltrexone
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Specific Antidote to Benzodiazepines?
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Flumazenil
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Specific Antidote to TCA's?
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NaHCO3 (serum alkalinization)
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Specific Antidote to Heparin?
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Protamine
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Specific Antidote to Warfarin?
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Vitamin K
Fresh Frozen Plasma |
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Specific Antidote to tPA or Streptokinase?
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Aminocaproic Acid
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Specific Antidote to Theophylline?
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Beta-Blocker
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Sx's of Lead Poisoning?
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Burton's Lines
Lines on Epiphyses of long bones on x-ray Encephalopathy Erythrocyte Basophilic Stippling Abdominal Colic Sideroblastic Anemia Wrist and Food Drop |
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Mnemonic for Lead Sx's?
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L = lead lines
E = encephalopathy and erythrocyte baso stippling A = Abd colic and Anemia D = drops and dimercaprol and eDta |
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Different Rx's for Lead poisoning for different pts?
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Adults get Dimercaprol and EDTA as first line
Kids get Succimer |
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How does Iron Poisoning kill you?
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Cell death due to peroxidation of membrane lipids
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Sx's of Iron Poisoning?
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Acute: gastric bleeding
Chronic: metabolic acidosis, scarring leading to GI obstruction |
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Which drugs can cause Atropine-like SE's on the CV system?
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Tricyclics
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Which drugs can cause Coronary Vasospasm?
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Cocaine
Sumatriptan |
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What drugs can cause Cutaneous Flushing (CV system)?
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Niacin
CCB's Adenosine Vancomycin |
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What drugs can cause Dilated Cardiomyopathy?
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Doxorubicin (adriamycin)
Daunorubicin |
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What drugs can cause Torsades de pointes?
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Class III Antiarrhythmics (sotalol)
Class IA Antiarrhythmics (quinidine) Cisapride |
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What drugs can cause Agranulocytosis?
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Clozapine
Carbamazepine Colchicine Propylthiouracil Methimazole |
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What drugs can cause Aplastic Anemia?
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Chloramphenicol
Benzene NSAIDs Propylthiouracil Methimazole |
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What drug can cause a Positive Direct Coombs Test and Hemolytic Anemia?
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Methyldopa
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What drug causes Gray Baby Syndrome?
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Chloramphenicol
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What can cause Hemolysis in G6PD Deficient patients?
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Isoniazid (INH)
Sulfonamides Primaquine Aspriin Ibuprofen Nitrofurantoin |
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What Drugs can cause Megaloblastic Anemia?
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Phenytoin
Methotrexate Sulfa Drugs |
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What class of drugs can have Thrombotic Complications?
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OCP's
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What class of drugs can cause coughing?
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ACE-I's
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What Drugs can cause Pulmonary Fibrosis?
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Bleomycin
Busulfan Amiodarone |
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What drugs can cause Acute Cholestatic Hepatitis?
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Macrolides
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What drugs can cause focal to massive hepatic necrosis?
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Halothane
Valproic Acid Acetaminophen Amanita phalloides |
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What drugs can cause Hepatitis?
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INH
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What drugs can cause Pseudomembranous colitis?
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Clindamycin
Ampicillin |
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What drugs are associated with causing Adrenocortical Insufficiency?
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Glucocorticoid withdrawal (HPA Suppression)
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Which Drugs can cause Gynecomastia?
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Spironolactone (Some)
Digitalis (Drugs) Cimetidine (Create) Alcohol (Awesome) Estrogens Ketoconazole (Knockers |
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Which drugs can cause hot flashes?
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Tamoxifen
Clomiphene |
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What drugs can cause Gingival Hyperplasia?
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Phenytoin
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What drugs can cause Gout?
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Furosemide
Thiazides |
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What drugs can cause Osteoporosis?
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Corticosteroids
Heparin |
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What drugs can cause Photosensitivity?
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Sulfonamides
Amiodarone Tetracycline |
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What drugs can cause Stevens-Johnson Syndrome?
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Ethosuximide
Lamotrigine CarbamazepinePhenobarbital Phenytoin Sulfa Drugs Penicillin Allopurinol |
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Drugs that can cause a SLE-like Syndrome?
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Hydralazine
INH Procainamide Phenytoin |
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Drugs than can cause Tendonitis, tendon rupture, and cartilage damage (kids)
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Fluoropuinolones
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What drugs can cause Fanconi's Syndrome?
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Expired Tetracycline
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What drugs can cause Interstitial Nephritis?
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Methicillin
NSAIDs Furosemide |
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What drugs can cause Hemorrhagic Cystitis?
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Cyclophosphamide
Ifosfamide |
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How do you prevent Hemorrhagic Cystitis caused by Ifosamide?
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Coadminister w/ mesna
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What is Cinchonism and what drugs cause it?
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Caused by Quinidine or Quinine
Sx's hearing loss or ringing in ears blurred vision or blindness arrhythmias |
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What Drugs can cause Diabetes Insipidus?
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Lithium
Demeclocycline |
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What drugs can cause Parkinson-like-syndrome?
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Haloperidol
Chlorpromazine Reserpine Metoclopramide |
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What drugs can cause Seizures?
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Bupropion
imipenem/cilastatin Isoniazid |
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What drugs can cause Tardive Dyskinesia?
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Antipsychotics
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What drugs can cause Disulfiram-like reactions?
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Metronidazole
certain Cephalosporins Procarbazine 1st Gen Sulfonylureas |
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What drugs can cause nephro and neuro-toxicity?
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Polymyxins
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What drugs can cause both nephrotoxicity and ototoxicity?
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Aminoglycosides
Vancomycin Loop Diuretics Cisplatin |
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7 Inducers of P-450 and their mnemonic
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Quinidine
Barbituates St. John's Wart Phenytoin Rifampin Griseofulvin Carbamazepine Queen Barb Steals Phen-phen and Refuses Greasy Carbs |
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Kicker about Quinidine and P450?
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it can inhibit and induce, but the inducing is more important
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6 Inhibitors of P450?
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Sulfonamides
Isoniazid Cimetidine Ketoconazole Erythromycin Grapefruit Juice SICKEG |
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Drugs that inihibit Ethanol metabolism and what they specifically do?
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Fomepizole inhibits alcohol dehydrogenase (great for staying drunk or fixing methanol/ethylene glycol poisoning)
Disulfiram inhibits Acetylaldehyde dehydrogenase --> super hangover |
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who are Sulfa Drugs?
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Furosemide
Thiazides TMP-SMX Probenecid Celecoxib Sumatriptan Sulfasalazine Sulfonylureas |
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Sx's of Sulfa allergy?
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Fever
Pruritic rash Stevens-Johnson Syndrome Hemolytic Anemia Thrombocytopenia Agranulocytosis Urticaria |
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Common Drug Suffixes and what they are used for? ex?
-afil |
Erectile Dysfxn
sildenafil |
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Common Drug Suffixes and what they are used for?
-ane |
Inhalational general anesthetic
halothane |
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Common Drug Suffixes and what they are used for?
-azepam |
benzodiazepine
diazepam |
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Common Drug Suffixes and what they are used for?
-azine |
Phenothiazines
neuroleptic, antiemetic ex: chlorpromazine |
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Common Drug Suffixes and what they are used for?
-azole |
Antifungal
ex: ketoconazole |
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Common Drug Suffixes and what they are used for?
-barbital |
Barbituate
ex: phenobarbital |
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Common Drug Suffixes and what they are used for?
-caine |
local anesthetic
ex: lidocaine |
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Common Drug Suffixes and what they are used for?
-cillin |
Penicillins
ex: methicillin |
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Common Drug Suffixes and what they are used for?
-cycline |
antibiotic, Protein Synthesis Inhibitor
ex: tetracylcine |
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Common Drug Suffixes and what they are used for?
-etine |
SSRI
ex: fluoxetine |
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Common Drug Suffixes and what they are used for?
-ipramine |
TCA
ex: imipramine |
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Common Drug Suffixes and what they are used for?
-navir |
Protease Inhibitor
ex: saquinavir |
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Common Drug Suffixes and what they are used for?
-olol |
Beta Blocker
propranolol |
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Common Drug Suffixes and what they are used for?
-operidol |
Butyrophenone's
neuroleptic ex: haloperidol |
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Common Drug Suffixes and what they are used for?
-oxin |
Cardiac glycoside (inotropic)
ex: digoxin |
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Common Drug Suffixes and what they are used for?
-phylline |
Methylxanthine
ex. theophylline |
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Common Drug Suffixes and what they are used for?
-pril |
ACE Inhibitor
ex. captopril |
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Common Drug Suffixes and what they are used for?
-terol |
Beta2-agonist
ex: albuterol |
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Common Drug Suffixes and what they are used for?
-tidine |
H2 Antagonist
ex: Cimetidine |
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Common Drug Suffixes and what they are used for?
-triptan |
5-HT-1a agonists (migraines)
ex: Sumatriptan |
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Common Drug Suffixes and what they are used for?
-triptyline |
TCA's
ex: Amitriptyline |
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Common Drug Suffixes and what they are used for?
-tropin |
Pituitary Hormones
ex: somatotropin |
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Common Drug Suffixes and what they are used for?
-zosin |
Alpha-1 antagonist
ex: Prazosin |
