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13 Cards in this Set

  • Front
  • Back
Meningitis Infection:

Pharynx → Lymphatics → Meninges
Haemophilus influenzae

most common in infants and young children
Meningitis Infection:

Middle Ear → Contiguous Ts → Meninges
S pneumoniae's usual MO

may also enter via hematogenous dissemination from blood
Meningitis Infection:

Traumatic Wound → Leaking CSF → Meninges
S aureus meningitis/abscess
Meningitis Infection:

Pharynx → Blood → Choroid Plexus → Meninges
Neisseria meningitidis

transmission via respiratory droplets
5% of general pop aSx carrier w/in nasopharynx

Rarely carriers hematogenously disseminate

SSx: Petechial Skin Lesions, Waterhouse Friderichsen Sro:rapid hypotension and death
Meningitis Infection:

Lungs → Blood → Meninges
M tb or S pneumo

Mtb presents as chronic meningitis (Marked ↑ protein, slow progression, mild mononuclear infiltrate)

S pneumo usually enters via direct invasion from otitis media, presents as bacterial (mild ↑ protein, rapid progressino, PMN infiltrate)
S aureus meningitis:

route of infx
Traumatic Wound → Leaking CSF → Meninges

may also produce abscess via same route.
Neisseria
meningitis:

route of infx
Pharynx → Blood → Choroid Plexus → Meninges
transmission via respiratory droplets
5% of general pop aSx carrier w/in nasopharynx

Rarely carriers hematogenously disseminate

SSx: Petechial Skin Lesions, Waterhouse Friderichsen Sro:rapid hypotension and death
S pneumo
meningitis:

route of infx
Middle Ear → Contiguous Ts → Meninges

may also enter via hematogenous dissemination 2° to pneumonia
Mtb
meningitis:

route of infx
Lungs → Blood → Meninges

Mtb presents as chronic meningitis (Marked ↑ protein, slow progression, mild mononuclear infiltrate)

[a route also used by S pneumo, tho S pn 1° route is direct invasion from middle ear]
Haemophilus influenzae
meningitis:

route of infx
Pharynx → Lymphatics → Meninges

most common in infants and young children
HSV1 presentation:

1° vs Reactivation
1° gingivostomatitis: involves most of gums and much or oral mucous membrane

Recurrent: unilateral, area involved 1/10th the size of original; tend to favor facial skin around muscoal orifices
CMV reactivation
interstitial pneumonitis, retinitis, hepatitis, colitis and generalized disease
At what T cell count are HIV+ pts immunocompromised
<200