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31 Cards in this Set
- Front
- Back
|
kids
2/3 |
ALL
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most responsive to therapy
|
ALL
|
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most common in adults
|
AML
CLL |
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spleen / liver enlarged
LN enlarged |
ALL
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fever
ESR high |
ALL
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absence of granulocytes
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infection
inflammation |
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absence of granulocytes
thrombocytopenia anemia |
acute leukemias
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malignant prolif of white blood cell precursors in
1-bone marrow 2-lymph node |
acute leukemias
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30,000-100,000
immature forms myeloblasts/lymphoblasts |
acute leukemia
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null cell
not T/B cell |
acute leukemia
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insidious onset
recurrent hemorrhage above 100,000 philadelphia chromosome |
chronic leukemia
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uncontrolled increase of white blood cells=leukocytes
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leukemia
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leukocytes
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defend body against infection
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most malignant
|
AML
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least malignant
|
CLL
|
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2 distinct phases
invariably fatal |
CML
|
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leukemia classified by
|
dominant cell type
duration from onset to death |
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leukemic cells accumulate >
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lessen production of erythrocytes
platelets leukocytes |
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chromosome marker
|
CML
|
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|
philadelphia
|
CML
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long arm is translocated
|
philadelphia
|
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what induces chromosomal abnormality
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radiation
carcinogenic chemicals |
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overgrowth of granulocytic precursors
=myeloblast =promyelocytes |
CML
|
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insidious
blastic crisis |
CML
|
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risk factors for leukemia
|
1-genetic=down> acute
2-chemical 3-radiation 4-virus= HTLV-1 |
|
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60 YRS OLD
|
CLL
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3-5
|
ALL
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MOSTLY ADULTS
|
AML
|
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OVER 60
|
CLL
|
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ANY AGE
|
CML
|
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abnormal small lymphocytes in
-lymphoid -blood -bone marrow |
CLL
|
