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26 Cards in this Set

  • Front
  • Back
Annual Pap smear reduces a woman's risk of dying of cervical CA by how much ?
90%
6th leading cause of CA death in women.
cervical cancer
Number of deaths / year due to cervical CA
5000
#1 CA killer of women in developing countries
Primary cause of cervical CA.
HPV
Cases of cervical CA dx annually.
15,000
Annual Pap smears.
anyone who has reached 18 or has begun sexual activity
cervical transformation zone ?
squamo-columnar junction
sample the endocervical canal with ?
a cytobrush
Within the layer of cells that form the surface or lining of an organ.
intraepithelial
Persistent infection & progression to CA
HSIL
Preceed directly to colposcopy.
ASC-H (H -Cannot R/O High grade lesion)
LSIL
HSIL
Bethesda mapping:
LSIL
CIN-I
MCD (mild cervical dysplasia)
HPV infectious changes
Bethesda mapping:
HSIL
CIN-II (moderate dysplasia)
CIN-III (severe dysplasia) = CIS
Colposcopy indications
ASC-US for 2 years.
ASC-H (means "ASC- cannot exclude HSIL")
LSIL (CIN-I, MCD (mild cervical dysplasia), HPV inf changes)
HSIL (CINII, CINIII)
Abnormal colposcope findings:
acetowhite epithelium
atypical vessels
mosaicism
punctuations
CIN-II, III tx ?
conization
reversible ?
not reversible ?
dysplasia & metaplasia
neoplasia (BM intact = CIS)
Cervical ds progression:
dysplasia
CIN
invasive carcinoma
Pap smear findings:
Negative for intraepithelial lesion
Atypical squamous cells (ASC-US, H)
LSIL
HSIL
SCC
7 years
4 years
LSIL to cervical CA
LSIL to HSIL
LEEP & Lletz for:
HSIL (CIN II or CIN II)
top hat procedure
endocervix & exocervix
90% of all cervical cancers
10% of all cervical cancers
SCC
Adenocarcinoma
SCC cervical CA types
large-cell keratinizing
large-cell non-keratinizing
small cell
Clear cell adenocarcinoma:
DES in utero
Classic cervical CA presentation:
post-coital bleeding