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26 Cards in this Set
- Front
- Back
Annual Pap smear reduces a woman's risk of dying of cervical CA by how much ?
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90%
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6th leading cause of CA death in women.
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cervical cancer
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Number of deaths / year due to cervical CA
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5000
#1 CA killer of women in developing countries |
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Primary cause of cervical CA.
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HPV
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Cases of cervical CA dx annually.
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15,000
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Annual Pap smears.
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anyone who has reached 18 or has begun sexual activity
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cervical transformation zone ?
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squamo-columnar junction
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sample the endocervical canal with ?
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a cytobrush
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Within the layer of cells that form the surface or lining of an organ.
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intraepithelial
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Persistent infection & progression to CA
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HSIL
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Preceed directly to colposcopy.
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ASC-H (H -Cannot R/O High grade lesion)
LSIL HSIL |
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Bethesda mapping:
LSIL |
CIN-I
MCD (mild cervical dysplasia) HPV infectious changes |
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Bethesda mapping:
HSIL |
CIN-II (moderate dysplasia)
CIN-III (severe dysplasia) = CIS |
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Colposcopy indications
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ASC-US for 2 years.
ASC-H (means "ASC- cannot exclude HSIL") LSIL (CIN-I, MCD (mild cervical dysplasia), HPV inf changes) HSIL (CINII, CINIII) |
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Abnormal colposcope findings:
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acetowhite epithelium
atypical vessels mosaicism punctuations |
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CIN-II, III tx ?
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conization
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reversible ?
not reversible ? |
dysplasia & metaplasia
neoplasia (BM intact = CIS) |
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Cervical ds progression:
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dysplasia
CIN invasive carcinoma |
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Pap smear findings:
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Negative for intraepithelial lesion
Atypical squamous cells (ASC-US, H) LSIL HSIL SCC |
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7 years
4 years |
LSIL to cervical CA
LSIL to HSIL |
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LEEP & Lletz for:
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HSIL (CIN II or CIN II)
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top hat procedure
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endocervix & exocervix
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90% of all cervical cancers
10% of all cervical cancers |
SCC
Adenocarcinoma |
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SCC cervical CA types
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large-cell keratinizing
large-cell non-keratinizing small cell |
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Clear cell adenocarcinoma:
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DES in utero
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Classic cervical CA presentation:
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post-coital bleeding
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