Bloodimmune

Front 1

Can trauma cause the release of WBC from the marrow?

Back 1

Yes. The majority of WBC are stored in the bone marrow, waiting for an increased level of cytokines to stimulate their release. However, trauma can cause a premature release of WBC into the circulation. This would not be due to an inflammatory response.

Front 2

What is the proper pathway for the extrinsic clotting pathway/

Back 2

The extrinsic pathway involves damage to the tissue, then the subsequent formation of prothrombin activator. tissue trauma results in the release of tissue factor or tissue thromboplastin, whichs functions as a proteolytic enzyme. the binding of tissue factor with factor V11 results in an activation of factor X. There is then a subsequent activation of prothrombin activator, conversion of prothrombin to thrombin, and conversion of fibrinogen to fibrin threads. The extrinsic pathway is fast b/c of the small number of enzymatic reactions.

Front 3

During the 2nd trimester of pregnancy, where is the predominant site of RBC production?

Back 3

RBC production begins in the yolk sac during the first trimester. It then decreases at the start of the 2nd trimester, and the liver becomes the predominant source of red cell production. During the 3rd trimester, RBC production increases from the bone marrow and continues throughout life.

Front 4

Helper T cells are destroyed by the AIDS virus, leaving the patient unprotected against infectious diseases. TRUE/FALSE

Back 4

TRUE.

Front 5

Monocytes circulate and then move into the interstitium, where they expand to become macrophages. macrophages, if not activated can remain in the tissue for the life of a person. TRUE/FALSE

Back 5

TRUE.