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18 Cards in this Set
- Front
- Back
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Different Types of Transfused Products
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Whole Blood
Red Blood Cells Leukocyte Reduced RBC's Platelet Concentrate Granulocyte Concentrate Fresh Frozen Plasma Cryoprecipitate Plasma Derivatives |
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Whole Blood
1. Uses 2. Limitations 3. Possible Rxns |
1. Increase Blood Volume and O2-carrying capacity at same time
2. No viable Platelets or Granulocytes. Also, reduced V and VIII 3. hemolytic, febrile, allergic, infectious, hypervolemic |
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Red Blood Cells
1. uses 2. limitations 3. reactions |
1. increase O2 carrying capacity
2. not for nutritional def. and no viable plts or grans 3. same as whole blood w/o hypervolemic |
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Leukocyte Reduced RBC's
1. why? |
1. Decrease risk of: Febrile Rxns, CMV transmission, HLA alloimmunization
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Platelet Concentrate
1. Uses 2. Possible Rxns |
1. Thrombocytopenia
Thrombocytopathy 2. Febrile, Allergic, Infectious |
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Granulocyte Concentrate
1. Uses 2. Limitation |
1. Fever
Neutropenia Bacterial Infection that doesn't respond to Antibiotics BM Hypoplasia 2. Not for prophylaxis Febrile and/or pulmonary rxns |
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Fresh Frozen Plasma
1. uses 2. limitation |
1. Coagulation Factor Replacement
2. Not for volume or protein replacement Not a Concentrate |
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Cryoprecipitate
1. Constituents |
1. Factor VIII
Fibrinogen Von Willebrand Factor Factor XIII |
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Plasma Derivatives:
Different kinds and examples |
1. Coagulation Factor Concentrates
Factor VIII Factor IX Anti-Inhibitor Complex Antithrombin III 2. Volume Expanders Albumin Plasma Protein Fraction 3. Immune Globulins Immune Serum Globulin Rh Immune Globulin |
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Factor VIII Concentrate
1. uses |
AntiHemophilia A
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Factor IX Concentrate
1. uses 2. Cautions |
1. Hemophilia B
Factor VIII Inhibitors 2. Risk of Thrombosis Risk of Transfusion Transmitted Diseases Risk of nonhemolytic transfusion rxns |
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Albumin and Plasma Protein Fraction
1. Uses 2. limitations 3. cautions |
1. Acute hypovolemia
2. Not for Chronic Hypoproteinemia No Coag factors or gamma globulin expensive 3. Hypervolemia |
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Types of Therapeutic Apheresis
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1. Plasma
2. Platelet 3. Leukocyte 4. Red Cell |
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Plasmapheresis
1. Rationale 2. Example |
1. Remove Ig's or pathogenic substance
2. Myeloma with hyperviscosity (MM) TTP |
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Thrombopheresis
1. Rationale 2. Example |
1. Reduce risk of hemorrhage or thrombosis
2. Essential Thrombocythemia |
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Leukopheresis
1. Rationale 2. example |
1. Reduce Leukostasis
2. Leukemia |
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Erythropheresis
1. Rationale 2. Example |
1. Exchange abnormal cells
2. Sickle Cell Crisis |
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Complications of Apheresis
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Hypotension
Syncope fluid overload resp/cardiac arrest anaphylaxis noncardiogenic pulmonary edema seizures loss of venous access (thrombosis, etc) |
