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43 Cards in this Set
- Front
- Back
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what are the low grade lymphomas
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CLL/SLL
marginal zone MALT follicular |
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t(14;18)
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follicular lymphoma
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gene associated with t(14;18)
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BCL2 and heavy chain
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what are the aggressive B cell lymphomas?
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diffuse large cell
mediastinal large cell primary effusion mantle cell burkitt's |
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t(8;14)
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burkitt
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t(2;8) and t(8;22)
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burkitt
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gene associated with t(8;14)
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C-MYC
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unusual lymphomas
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CNS lymphoma
cutaneous T cell mante cell anaplastic large cell |
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what cells proliferate in cutaneous T cell lymphoma?
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CD4+ lymphocytes
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2 syndromes associated with cutanous T cell lymphoms
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mycosis fungoides-cutaneous involvement
cezary syndrome - CTLC cells circulate |
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t(11;14)
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mantle cell
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gene associated with t(11;14)
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BCL-1 and cyclin D
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CD5 and CD23
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mantle cell lymphoma
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t(2;5)
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anaplastic large cell lymphoma (aggessive T cell)
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AIDS defining lymphoma
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CNS lymphoma
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CD15 and CD30
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lacunar cells in HL
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Auer rods present in
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AML
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most acute leukemia in adults is
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AML
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most acute leukemia in kids is
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ALL
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t(9;22)
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PreB ALL and CML
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genes associated with t(9;22)
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BCR-ABL
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RARa-PML mutation found in
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AML M3
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TEL-AML mutation found in
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preB ALL
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t(12;21)
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preB ALL
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ex of point mutation in acute leukemia
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activated RAS in AML and ALL
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which mutations mean poor prognosis in AML
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5q-
monosomy 7 trisomy 8 11q23 |
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t(15;17)
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AML M3 - good prognosis
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gene associated with t(15;17)
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PML-RARa
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myeloperoxidase and sudan black positive in
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AML
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CD 13 and 33
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AML
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PAS and acid phosphatase positive in
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ALL
and M6 AML |
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CD19, 22, and maybe 10
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ALL
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testicular swelling found in
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ALL
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DIC almost always present in
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ALL M3
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prognosis of Ph+ in ALL
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poor
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markers of good prognosis in AML
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t(8,21)
t(15;17) inv(16) |
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smudge cells are foud in
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CLL
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CD: 5, 19, 20, 23
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CLL
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poor prognosis in CLL marked by
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trisomy 12, p53
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13q14 mutation prognosis
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good prognosis in CLL
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LDH, CD38+, ZAP70+ means…
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poor prognosis in CLL
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high LDH, B2M, CRP means…
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poor prognosis in Multiple Myeloma
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t(4;14) , t(14;16) , 17p- means…
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poor prognosis in Multiple Myeloma
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