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47 Cards in this Set

  • Front
  • Back
What is the indication for heparin?
Prevent DVT, PE, Stroke
What are the side effects for heparin?
Bleeding
Cyanosis
Temperature
Pain and Tingling
HIT- allergic response
What are the nursing implications for heparin?
-always check PTT before giving
Normal: 40 sec
If on heparin - should be 60 to 80 sec
- Dont give if more than 80 sec
-Monitor/educated bleeding gums, nose
-Use electric razors
-If cut, apply pressure for 10 min with no peeking
*check lab for platelet count*
*Give Protamine sulfate for OD
What is HIT?
Heparin Induced Thrombocytopenia - an allergic reaction to heparin. FIRST SIGN: Low platelet counts below 150,000
What is the antidote for a heparin OD?
Protamine Sulfate
What is the indication and side effects for enoxaparin (Lovenox)?
Prevent DVT, PE, MI, Stroke

SE:
-Bleeding: less than heparin
-Cyanosis
-Temp
-Pain and Tingling
-Allergy (HIT) - 10X less likely
What is the indication and side effects for dalteparin (Fragmin)?
Prevent DVT, PE, MI, Stroke

SE:
-Bleeding: less than heparin
-Cyanosis
-Temp
-Pain and Tingling
-Allergy (HIT) - 10x less likely
What is the indication and side effects for tinzaparin (Innohep)?
Prevent DVT, PE, MI, Stroke

SE:
-Bleeding: less than heparin
-Cyanosis
-Temp
-Pain and Tingling
-Allergy (HIT) - 10X less likely
What are the nursing implications for enoxaparin (Lovenox)?
*LEAVE AIR BUBBLE*
-Inject in lovehandles
-Always use 90 degree angle
-Check platelet counts
What are the nursing implications for dalteparin (Fragmin)?
*LEAVE AIR BUBBLE*
-Inject in lovehandles
-Always use 90 degree angle
-Check platelet count
What are the nursing implications for tinzaparin (Innohep)?
*LEAVE AIR BUBBLE*
-Inject in lovehandles
-Always use 90 degree angle
-Check platelet count
What is the indication and side effects for fondaparinux (Arixtra)?
to prevent DVTs

SE:
-Bleeding
-Anemia, fever
-No chance of HIT - not heparin-derived.
What is the indication and side effects for danaparoid (Organon)?
To prevent DVTs

SE:
-Bleeding
-Anemia, fever
-No chance of HIT - not heparin-derived
For whom is Arixtra and Organon contraindicated for?
-Patients with kidney impairment
-Weight < 110 lbs
-Elderly
-Plateles <100,000
What are the nursing implications for Arixtra and Organon?
-Once a day administration
-No PTT or PT needed
-Watch for bleeding
What are the indications for warfarin (Coumadin)?
Drug of choice for longterm prevention of DVTs
-Atrial Fibrillation
-Heart valve replacement
What are the side effects for warfarin (Coumadin)?
-Hemorrhage/Bleeding
-Red or black stools
-Bleeding gums, nose, urine
-Skin rash or bruising
What are the nursing implications for warfarin (Coumadin)?
*Monitor PT values: normal = 12 sec.
-Educate about electric razor
-Educate signs of bleeding
-No ASA or NSAIDS
-Keep Vitamin K intake constant
-Vitamin K is the antidote
What is the antidote for a warfarin (Coumadin) OD?
Vitamin K
What is the indication and side effects for streptokinase (Sstreptase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the indication and side effects for alterplase (tPA, Activase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the indication and side effects for tenecteplase (TNKase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the indication and side effects for reteplase (Retavase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the indication and side effects for antistreplase (Eminase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the indication and side effects for urokinase (Abbokinase)?
Ind: Acute MI, DVT, PE

SE:
-Bleeding
-Intracranial bleeding
*Allergic reaction
-Hypotension
-Fever
What is the first thing to watch for when administering a clot buster (-ase)? What would you do?
Allergic reaction. Discontinue and administer epinephrine, antihistamine, or steriod.
What do clot busters do? Who can administer them?
Dissolve thrombi that have already formed. Only given by skilled clinicians - serious risk of bleeding.
What is the indication for aspirin (ASA)?
prevention of MI and stroke
What are the side effects for aspirin (ASA)?
GI bleeding
hemorrhagic stroke
What are the nursing implications for aspirin (ASA)?
-Use enteric-coated forms
-Monitor for bleeding (GI)
-Avoid other anticoagulants
-Stop taking at least 10 days before surgery
What is the indication for clopidogrel (Plavix)?
Prevention of ischemic stroke and TIA
What are the side effects of clopidogrel (Plavix)?
-GI bleeding
-hemorrhagic stroke
-abdominal pain
-dyspepsia
What is Aggrenox indicated for?
extended release aspirin used to prevent recurrent ischemic stroke in patients with a previous stroke or TIA. Prevents clots.
What is epoetin alfa (Erythropoietin , Epogen, Procrit) indicated for?
Anemia with CRF, AIDS, or chemo
What are the side effects for epoetin alfa?
-Hypertension
-Tachycardia
-Seizure
-Pain in bones/joints
-chest pain
-clotting of shunt for dialysis
What are the nursing implications for epoetin alfa?
-Monitor labs
-Costly treatment
-Monitor BP - medicate prn
-contraindicated in patients with HTN.
-Need iron supplement
-Need to increase dietary intake of iron, folic acid, B12
What is the indication for darbapoetin alfa?
Long acting erythropoietin for pts with CRF.
What is the indication for filgrastim (Neupogen)?
Severe chronic neutropenia (lack of WBCs)
What are the side effects of filgrastim (Neupogen)?
*Bone pain*
leukocytosis
What are the nursing implications for filgrastim (Neupogen)?
*Store at ROOM TEMP*
-Monitor CBCs
What is the indication for pegfilgrastim (Neulasta)?
long acting G-CSF
What is the indication for oprelvekin (Interleukin-11, Neumega)?
Stimulates the production of platelets for patients on chemotherapy.
What are the side effects for oprelvekin (Interleukin-11, Neumega)?
-Fluid retention
-Cardiac Dysrhythmias
What are the nursing implications for oprelvekin (Interleukin-11, Neumega)?
-Use within 3 hours
-Monitor CBC/Platelets
-Monitor fluid/electrolyte status
What is the normal range for RBCs?
4.2 - 6.2
What is the normal range for WBCs?
5,000 - 10,000
What is the normal range for platelets?
150,000 - 400,000