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7 Cards in this Set

  • Front
  • Back

3 main processes in Platelet Plug Formation?

Platelet Adhesion to damaged portion of blood vessel walls



Platelet Release Response when platelets stimulate each other with newly formed extensions to release chemicals from their vesicles



Platelet Aggregation when sticky platelets adhere together forming the platelet plug

3 mechanisms of Hemostatic Response:

Vascular Spasm


Platelet Plug Formation


Blood Clotting

Vascular Spasm

damaged arteries and arterioles contract the smooth muscle in their walls to reduce blood loss

Vascular Spasm is due to what 3 things?

Damage of the smooth muscle in the wall of the vessel


Chemicals releaed by activated platelets


Reflexes stimulated by pain receptors

Blood Clot

Formed from a network of insoluble fibres called fibrin that trap formed elements

3 main stages of Fibrin Formation:

Production of prothrombinase;



Prothrombinase converts prothrombin (plasma protein) into thrombin (enzyme);



Thrombin converts soluble fibrinogen into insoluble fibrin, which forms the threads of the clot

The enzyme prothrombinase can be formed in two ways:

Intrinsic Pathway



Extrinsic Pathway