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23 Cards in this Set
- Front
- Back
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Is albumin in higher concentration in the plasma, lymph or interstitial fluid?
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plasma
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How much of a role does albumin play in the colloid osmotic pressure of plasma?
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albumin accounts for the majority of the colloid pressure of the plasma
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What does colloid osmotic pressure depend on and what about albumin makes it have such a great effect?
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colloid osmotic pressure depends on the hydrophilicity of a protien and albumin is one othe the most hydrophilid protiens studied
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What is an abnormal level for albumin?
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below 2 g/dl
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What does albumin bind?
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a great variety of drugs and small molecules, very versatile, has sites for bilirubin, heme, cotisol...
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how do albumin levels affect drug levels?
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free serum albumin will reversibly bind to some drugs
if plasma albumin levels are low than there will be more unbound drug than anticipated which could be toxic |
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What blood protien is involved in transporting retinol from the liver to other tissues and in transporting thyroid hormones?
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Transthyretin, aka prealbumin
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What protien is more sensitive to nutritional levels than albumin?
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transthyretin
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How does transthyretin transport retinol?
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transthyretin is in the blood and it can bind to retinol binding protein which is bound to retinol when the liver releases it
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What protien transports thyroid hormone and binds thyroxine 100 times stronger than transthyretin?
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thyroxine binding protein
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what protien binds to glucocorticoids?
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transcortin
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What escapes from ruptured erythrocytes as an alpha-beta dimer?
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hemoglobulin
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What binds to alpha beta dimer hemoglobulin in order to prevent renal excretion and loss of iron?
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haptoglobin
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Ig found in tonsils and peyer's patches
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IgA
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most abundant Ig
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IgG
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Ig that can pass through placenta
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IgG
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Bence Jones Proteins
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tumor cells that have lost a lamda or gamma chain and are excreted in the urine
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Ig with the shortest half life
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IgE
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Ig that is dimer
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IgA
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Ig that fixes complement
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IgG
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main antigen in secondary response to antigen
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IgE
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has membrane bound secretory component that triggers transport across mucosa
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IgA
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mediates allergic reaction
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IgE
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