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75 Cards in this Set

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Plasma makes up __ % of the total blood and is itself
___ % water.
52 - 62%

91% water
The normal pH range of blood is:
7.35 - 7.45, slightly alkaline
Plasma carries many types of substances; ______ from the Gi tract to body, ______ products from body to kidneys, and _____ from endocrine glands to target organs. And antibodies.
Nutrients
Wast
Hormones
Plasma proteins include, clotting factors such as ____________ and __________ that are made in the liver and circulate until they meet damaged tissue and are activated to form a clot.
prothrombin
and
fibrinogen
The plasma protein that helps maintain blood volume by pulling tissue fluid into cappillaries is:
albumin
Red Blood cells are also called _________.
erythrocytes
What number of RBCs per cubic millimeter- volume of one droplet.
4.5 - 6 million
_______________ is the total blood cells measured by percentage of cells and plasma.
Hematocrit
Normal Hct (hematocrit) is _____ %.
38 - 48
The oxygen carring protein of RBCs are ?
hemoglobin
Each RBC contains about ______ million hemoglobin molecules, each of which can bind with ___ oxygen molecules.
300

4
Normal range of hemoglobin is _______ g/1--ml of blood.
12 -18%
The cells in the hemopoietic tissues that undergo mitosis to produce all the types of blood cells (mostly RBCs)are called:
stem cells
In a state of _________, the kidneys release erythyopietin which stimulates RBM to increase rate of production.
hypoxia
The extrinsic factor needed for DNA synthesis in the red bone marrow is ?
Vitamin B12
_____ factor: chemical produced by the lining of the stomach, it combines with ____ factor to prevent its deigestion and promotes absorption in the small intestine.
Intrinsic

extrinsic
_____ acid and Vit. ___ are required for DNA synthesis in stem cells.
Folic

B12
RBCs live for only _____ days, then become fragile and are destroyed.
120
What are big eaters, found in the liver, spleen and RBM.
macrophages
_______ is part of the Hgb(hemoglobin) molecule that can't be recycled; it is released bile.
Heme
When old RBCs are destroyed, the converted waste product _____ is then excreted by the bile.
bilirubin
IDA (Iron Deficiency Anemia)
is lack of dietary ____.
Iron (Fe)
_____ Anemia is deficiency of Vit B12 or Intrinsic factor.
Pernicious
____ anemia is a genetic disorder, deforming RBC and this clogs capillaries and causes them to _____.
SS (Sickle Cell)

rupture
____ anemia is caused by radiztion, or certain medications.
Aplastic
_____ anemia is any disorder that causes rupture of RBCs before the end of their normal life span.
Hemolytic
The red bone marrow produces ______________________.
all the types of blood cells.
Blood type refers to ________ present on the blood cells. These are inherited traits.
antigens
Type A person has A _____ and anit- __ antibodies.
antigen

B antibodies
Type B person has ___ antigen and anti-__ antibodies.
B

A antibodies
Type AB has A and B ______ but neither antibody.
antigens
Type O has ________ antigens, but anti-A and anti-B antibodies.
neither A or B
_____ factor is another antigen that may be found on the RBCs.
Rh
Rh positive = Rh factor is ______.
present
Rh ________ = Rh factor is not present.
negative
The Rh factor is an antigen thta is found on the RBCs of people who are Rh ________.
positive
Blood transfusion need to be of the same type and Rh of the recipient, or it causes _________.
agglutination
_________ is when RBCs clump together, then hemolysis- RMCs rupture.
Agglutioination
WBC (white blood cells) are also called ?
leukocytes
Normal WBC count is ______ thousand/mm3.
5 -10 thousand/mm3
WBC are classified in 2 groups; ___________ and ___________.
Granular

Agranular
Granular WBCs are produced in the _______.
RBM
Neutrophils, Eosinophils, and Basophils are ________.
granular or agranular
granular
Agranular WBCs are produced in the _______________.
lymphatic tissue of spleen, lymph nodes and Thymus and RBM.
Lymphocytes and monocytes are ___________.
granular or agranular
agranular
A CBC shows percentage of each type of __________.
leukocyte
The WMCs that carry out most phagocytosis of pahtogens are the _______________.
monocytes and neutrophils
The WBC that detoxifys foreign proteins is _____.
Eosinophils
The WBC that has a natural response of histamine and herparin is the ___________.
Basophils
Lymphocytes are 2 types of cells, what are they?
T cells and B cells
___cells recognize anitgens and destroy.
T
____ cells produce antibodies, fight the next time the antigens come in.
B
_BCs may travel to seek and destroy pathogens.
W
WBCs
Leukocytosis is: ____ WBC count and often indicate _________.
high

infection
Leukopenia is: _____ WBC count and maybe caused by ______.
low

disease
Leukemia is: ______ of leukocyte, _____production of immature WBCs.
cancer

over
Thrombocytes are also called _________.
platelets
Thrombocytes are _________ of cells.
fragments/ pieces
Normal platelet count is _________/mm3.
150,000 - 300,000
Thrombocytopenia is ________ platlet count.
low
Some stem cells become megakaryoctes, which _________ that enter circulation.
break up into pieces
Platelets survive ________ days if not used first.
5 - 9 days
Vascular spasm, Platelet plugs and Chemical clotting are ways the platelets ____________.
prevent blood loss/ hemostatsis
_____________ - platelets release serotonin, constricts blood vessels and blood clot stops hemorrage.
Vascular spasm
____________ - seals breaks in capillaries.
Platelet plugs
_________________ - rough surface in a blood vessel, begins in 15-120 seconds, and faster with more damage.
Chemical clotting
A blood clot is made of ?
Clots are made of this thread-like protein called ?
fibrin
An abnormal clot that forms on a rough surface in an intact vessel is called ?
a Thrombus
A clot circulating in the blood stream that lodges in and obstructs a vessel is ?
a Embolism
_________ is genetic, sex-linked trait, blood can't clot due to deficiency of clotting factor 8.
Hemophilia
________ have nuclei when mature.
WBCs
_______ tells body to get more RBCs.
hypoxia
______- measures % counts RBC and Hct.
CBC
___, _____ and _____ are formed in hematopoietic tissues; red bone marrow and lymphatic tissue (spleen, lymph nodes & thymus gland)
RBCs
WBCs
Platelets
Globulins - made in liver and transports _____.
fats