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13 Cards in this Set
- Front
- Back
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Na absorption |
Na/glucose or Na/AA co-transporter found in jejunum and ileum Na/H enchanger in duodenum and jejunum Na/H and Cl/HCO3 exchangers in ileum and proximal colon Epithelial sodium channel in distal colon |
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Cl absorption and secretion |
Passive absorption mostly in jejunum and distal colon, some in ileum |
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K absorption and secretion |
Passive K absorption in jejunum and ileum Passive K secretion in proximal and distal colon Active K secretion in proximal and distal colon Active K absorption in distal colon |
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Aldosterone effet on K secretion |
Aldosterone enhances K secretion by two mechanisms: 1. increases passive K secretion by increasing Na/K pump activity: increase sodium absorption to increase lumen negative charge which increases K secretion 2. Stimulate active K secretion by increasing activity of both apical K channels and basolateral Na/K pumps |
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Where does carbohydrate absorption occur? |
Mostly in duodenum, less in jejunum, even less in ileum |
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Where does calcium, iron, and folate absorption occur? |
Calcium, iron, and folate absorbed at proximal duodenum, immediately after pylori Calcium is absorbed also in jejunum and ileum |
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Where does bile acid absorption occur? |
Mostly occurs in the ileum Also occurs in duodenum, jejunum, and ascending colon |
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Where does cobalamin absorption occur? |
Cobalamin absorption occurs in ileum |
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What are the monosaccharide products? Where are they absorbed? |
Glucose, galactose, fructose Glucose and galactose absorbed with Na - SGLT1 Fructose absorbed through GLUT5 All three absorbed through basolateral GLUT2 |
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Stimulants of HCl secretion |
Acetylcholine Gastrin Histamine |
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Somatostatin |
Regulation of gastric acid secretion Decreases acid by acting on parietal cell D cells Important in antrum because stomach can handle all of the acid but the intestine doesn't have a barrier, so need to control acid with somatostatin |
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Activation of pepsinogen |
acidic pH |
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Where does majority of protein digestion and absorption occur? |
Jejunum |
