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7 Cards in this Set

  • Front
  • Back
What type of drug is Donezepil?
AChE inhibitor
How does Donezepil affect the course of AD?
Does NOT alter the course of AD
What two main types of drugs are employed in AD?
AChE inhibitors
NMDA-receptor antagonists
What type of drug is Memantine?
NMDA-receptor antagonist
(low-moderate affinity, NON-competitive inhibitor)
How does Memantine affect AD?
Shown to improve symptoms

Shown to reduce the rate of deterioation
(in moderate-severe AD)
What are secretases?
Enzymes that cleave amyloid precursor protein
(could play a rold in plaque aggregration)
How do NSAIDs affect AD?
Thought to offer modest prophylaxis via down-regulation of gamma-secretase