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16 Cards in this Set
- Front
- Back
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pre natal stages of hemopoiesis
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mesoblastic (blood islands in the yolk sac), hepatic, splenic, myeloid
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postnatal hemopoiesis location
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exclusively in bone marrow, skull ribs sternum vertebrae pelvis proximial end of femurs
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what is the common ancestor of myeloid and lymphocyte stem cells
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PHSC pluripotential stem cell
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hemopoiesis of erythrocytes
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CFU-GEMM--- BFU-E-------CFU-E---ERYTROCYTES
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steps after CFU-E
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proerythorblast- basophilic erythroblast- polychromatophilic erythroblast- normoblast or orthochromatophilic erythroblast (eccentric nucleus)--- reticulocyte (no nucleus)----mature erythrocyte
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what is the first step where no nucleus can be see in erythrocyte development
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reticulocyte
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granulocytopoiesis steps
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CFU- (EO, Ba, G- for neutrophil)---myeloblast--- promyelocyte---myelocyte---metamyelocyte---band (stab)--- eosinophil basophil or neutrophil
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special feature of the myelocyte
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specific granules discernible
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special features of the metamyelocyte
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indented nucleus
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hemopoiesis of monocytes
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CFU GEMM---CFU-GM--CFU-M---monoblast---- promonocyte--- monocyte----
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megakaryocyte hemopoiesis
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CFU-MEG--- megakaryoblast--- promegakaryocyte--- mature megakaryocyte
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maturation of the megakaryocyte
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exponential division of the committed cell, nuclear replication without cell division:endoreduplication (endomitosis), cytoplasmic maturation, platelet release
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platelet formation steps
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cytoplasmic invaginations surrounded by demarcation membranes, chains of platelets released into sinuses
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lymphocyte hemopoiesis
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PHSC---CFU-Ly---- (splits to CFU LyB or Lyt)---- lymphoblast---prolymphocyte---lymphocyte
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where does CFU LyT go to become immunocompetent
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thymus
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CFU-LyB goes where to become immunocompetent
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bone marrow
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