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30 Cards in this Set

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Bacteriophage
Viruses that infect bacteria

T4, lambda, phi29 are examples in lecture

In most phage, genome is dsDNA
Host species for T4 and phi phages
E. coli
Host species for lambda29 phage
Bacillus subtilis
Steps of replication
AIR EAR

Attachment
Injection (Entry)
Replication

Expression
Assembly
Release
Typical role of EARLY proteins
Involved in preparation for DNA replication
Typical role of LATE proteins
Involved in structural components
Lysogen
A cell carried an INTEGRATED phage genome
Prophage
The phage genome in a lysogen
Cell surface receptor for Rhinovirus
ICAM-1
Cell surface receptor for HIV-1
CD4
Chemokine (co-receptor) [CCR5 or CXCR4]
Cell surface receptors for Rabies virus
Acetylcholine receptor
Cell surface receptor for influenza
Sialic acid
Virus fusion protein of influenza
Hemagglutinin
Virus fusion protein of retroviruses
gp120
Location of fusion for influenza viruses
Endocytic vesicle
Virus types that FUSE with endocytic vesicles
Influenza virus (Orthomyxo)
Rhabdoviruses

Alphaviruses and ADENOviruses PENETRATE vesicles
Fuseon
Anti-HIV drug
Targets the membrane fusion process
Location of poxvirus replication
Cytoplasm
(unusual for DNA viruses)
Location of influenza replication
Nucleus
(unusual for RNA viruses)
Viruses that can cause cancer
KSHV
HPV
EBV
Hep B, C
HTLV-1
DNA polymerase used by papillomaviruses
HOST cell-encoded
N-protein
Coats RNA of MINUS strand viruses
Coating is there at ALL stages
Viruses that have sub-genomic mRNAs
Coronaviruses
Alphaviruses
Viruses with segmented RNA
BOAR

Bunyaviridae
Orthomyxoviruses
ARENAviruses
Reoviridae
VHS
HSV gene that causes degradation of host cell mRNAs

Only LATE HSV-1 mRNAs are spliced
(restriction against splicing is lifted)
Viruses that have a pre-formed, nucleic acid-free capsid
Herpesviruses
Reoviruses
Location that HSV buds through
Trans-Golgi membrane
This virus family can spread by promoting local areas of fusion
Herpesvirus

Virus passes through channel @ fusion site
Cell surface receptors for HSV-1
Heparan sulfate
Nectin 1
Circular DNA viruses
Papovaviridae
Hepadnaviridae

Herpesviridae DNA becomes circular during replication