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13 Cards in this Set

  • Front
  • Back
ventricular arrhythmias when used with halothane
Epi
How do small and large doses of Epi differ?
small - beta 2
large- alpha 1
which has the lowest incidence of cardiac arrhythmias?
dobutamine
dopamine
epi
isoproteronol
dobutamine
what increases as alkyl substituents on the catechol N increase in size
beta receptor affinity in relation to alpha receptors
What increases as you remove the OH from the ring and the beta carbon
lipophilicity --> CNS action
(amphetamine)
What happens if you make an alpha C substitution
block metabolism by MAO
--> prolong action
(ephedrine)
what causes reflex inc in HR and CO
alpha 1 antagonist
may cause postural hypotension, nasal stuffiness, reflex cardiac stimulation, and imaired ejaculation
prazosin
What causes dec Hr, and dec CO that is more pronounced during exercise?
propranolol
What is the net effect of propranolol in HT patients?
dec BP even though the beta 2 block effects inc TPR
-may be from dec cardiac output, dec renin or CNS mediated
What slows the recovery of glucose after insulin administration
propranolol
what may exacerbate insulin-induced hypoglycemia and mask reflex tachycardia normally seen?
beta antagonists
Where exactly does clonidine work?
alpha 2 receptors in medulla oblangata- vasomotor center in ventrerolateral reticular formation and NTS