Reading...
Play button
Play button
Use LEFT and RIGHT arrow keys to navigate between flashcards;
Use UP and DOWN arrow keys to flip the card;
H to show hint;
A reads text to speech;
8 Cards in this Set
- Front
- Back
|
Why is most blood that is given leukoreduced?
|
WBC induce HLA exposure and pts make antibodies to HLA antigens so in subsequent transfusions, can get reactions
|
|
|
In addition to HLA rxns, what negative side effect can WBC contaminants in packed red cells have?
|
WBC induce immune suppression even in healthy recipient. (T suppressor cells)
increased infection rates |
|
|
when you give platelets, each individual UNIT should increase platelet count by how much?
A DOSE of ___ units should raise the count by at least ____ |
Each individual unit should increase platelet count by 5 to 15,000.
Thus a dose of 6 units should raise the count by at least 30 K/ul |
|
|
why are platelets more likely to be contaminated with bacteria than blood?
|
They cannot be refrigerated
|
|
|
what is the first sign of a transfusion rxn?
|
Temp goes up by more than 2 derees, you must stop the transfusion; temperature spike is the first indicatory of a hemolytic reaction and we can’t afford that risk
|
|
|
what normally causes anaphylactic tranfusion rxns?
|
an IgA deficient person with anti-IgA antibodies gets blood with IgA in it
|
|
|
Why do you NEVER EVER run blood into a pt through a line that has other drugs running through it?
|
if it has a different tonicity, you could lyse the red blood cells
|
|
|
Most common reported cause of death from transfusion?
|
Transfusion related acute lung injury (TRALI)
Majority associated with granulocyte antibodies or HLA antibodies in DONOR that react with patient white cells. implicated in women donors who have had babies |
