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10 Cards in this Set

  • Front
  • Back
routes of administration for bisphosphonates
PO, IV
use of bisphosphonates
treatment and prevention of osteoporosis
MOA of bisphosphonates
inhibit osteoclast activity
osteopenia
low BMD, not low enough to be considered osteoporosis
directions for administration of bisphosphonates
take 30 minutes before a meal

stay upright for 30-60 minutes after dose


drink a full glass of water

Why are bisphosphonates given on an empty stomach?
very low bioavailability (0.7%)
suffix that indicates a bisphosphonates
-dronate
What two vitamins/mineral levels should be corrected or supplemented before starting bisphosphonate therapy?
Vitamin D and calcium
What mineral deficiency can be worsened by bisphosphonates?
Hypocalcemia
Which bisphosphonate SHOULD be given with food?
risedronate (Atelvia)