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17 Cards in this Set
- Front
- Back
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What is frequency coding a general feature of and how is the strength of a stimulus encoded?
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The PNS: Strength of a stimulus is encoded in frequency of AP's that are stimulated.
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what is spike timing?
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It is in the CNS, and it is how the information in then nervous system is carried
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When you increase the weight what affect does it have on the AP?
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Increasing the weight increases the frequency of an AP in a sensory neuron however does not affect the strength of an AP because an AP is a all or none event.
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What does an axon do?
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Axon sends output (AP's) and makes synapses
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What does a Dendrite do?
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receives input: synapses, sensory
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What are axons surrounded by?
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myelin from oligodendrocites
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What are the specific stains that stain only neurons and what happens?
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1. golgi silver stain, reduced AG and neuron is stained jet black
2. Nissl, stains rough ER by staining the rRNA and revealed the different layers of the cerebral cortex. |
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What is the difference between horseradish peroxides (HRP) and golgi?
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HRP enzymes have a useful amplification quality and stains jet black like golgi, but specific, unlike the golgi stain.
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If you put a fluorescent tag on an antibody, what can you see?
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Can see that this protein is localized here
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What do oligodendrocytes do and where are they?
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They make myelin and speed conduction of AP. In the CNS
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What do Astrocytes do and where are they?
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biochemical support of endothelial cells that form the blood–brain barrier, provision of nutrients to the nervous tissue, maintenance of extracellular ion balance, and a role in the repair and scarring process of the brain and spinal cord following traumatic injuries. They are in the CNS.
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What do Ependymal cells do and where are they?
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They line the walls of the ventricles (cavities in the brain) and make cerebrospinal fluid, which cushions the brain. In the CNS
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What do Radial glia do and where are they?
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Development role. In the CNS
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What do Micro glia do and where are they?
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immune function, more TBD. In the CNS
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What do Schwann cells do and where are they?
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make myelin in the PNS
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What are the rapid functions of glia?
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1. Myelin production--> speeds the conduction of AP's
2. K+ buffering--> astrocytes, as K+ leaves the cell during APs, K+ levels can get quite high w/o something to sequester it. 3 Excitability--> makes APs, release NTs 4. NT uptake--> astrocytes |
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What are the slow functions of glia?
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1. Blood brain barrier: astrocytes, keep things from leaving the capillary and getting into the brain
2. ependymal cells: CSF 3. microglia: scavenging function and immune function 4. Generation of neurons: radial glia 5. Guidance of axons to targets during development: radial glia 6. glia affect regeneration |
