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24 Cards in this Set
- Front
- Back
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what drugs bind to g protein coupled receptors
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opioids, cannabinoids, GHB, LSD
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what drugs bind to ionotropic receptors and ion channels
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nicotine, alcohol, benzo, phenylcyclidine, ketamine
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drugs that bind to transporters of biogenic amines
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cocaine, amphetamines, ecstasy
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what is the MOA of acute alcohol intoxication
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inhibits NMDA channel opening and enhances GABA
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what is the MOA of chronic alcohol
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increases NMDA receptor and decrease GABA
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what is the purpose of using Naltrexone
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reduced alcohol and opiate cravings and relapse
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what are five factors that precipitate violence
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intoxication, hallucination or delusions, poor impulse control due to neuro psych, character pathology chaotic ER
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what are the drugs of choice for tx violent behavior in the ER
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Benzo (lorazepam), typical antipsychotic (haloperidol, thorazine -aka chlorpromazine), atypical antipsychotic (ziprazidone, olanzapine)
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what are the different scores on a MMSE and what do they mean
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24-30 depressed without dementia
20-24 cognitive impairment <20 dementia, delerium, schizo, MR, affective disorders |
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what dz causes: hyperthermia, hyperreflexia, hypOtension, diaphoresis, confusion, and tremor
can lead to DIC or CV collapse |
serotonin syndrome
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what dz is this: fever. hypotension, diaphoresis, and death ..all secondary to psychotic process
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lethal catatonia
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what is the treatment for lethal catatonia
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fluids, electrolytes, nutrition, antipsychotic ( lorazepam)
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what does MAOI and tyramine interaction cause
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htn crisis
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what is the treatment for MAOI and tyramine interaction
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1. Nifedipine, 2. phenolamine 3. chlorpromazine
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what are the levels of triage for potentially dangerous patients
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level 1: not actively dangerous
level2: suicide precautions, assault precautions level three: requires seclusion or restraint, in danger of hurting others or self |
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__ ___ is the numer of ppl with illness at a specific point in time / total pop
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point prevalence
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____: quality f the measurements precision. Can be reproduced
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reliability
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in studies of ____ sensitivity is a measure of the number of true cases
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validity
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__ ___: number of events or conditions of interest
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numerator data
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__ __: number of ppl in pop of interest at risk of having an event
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denominator data
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what two factors represent frequency:
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incidence and prevalence
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what determines the burden of disease
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prevalence= incidence X duration
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___: the number of events in a defined time period divided by the avg pop at risk
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rate
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outbreak vs epidemic
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outbreak is localized and epidemic doesn't follow usual rate- it is in a widespread area
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