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13 Cards in this Set
- Front
- Back
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Stereotaxic Surgery
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When experimental devices are positioned in the brain.
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Bregma
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Point on the top of the skull where two major seams in the skull intersect.
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Stereotaxic Instrument
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It has a head holder (holds brain in place) and an electrode holder (holds the device that will be inserted).
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Lesion Methods
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The structure is destroyed, and once it recovers, the effects on the behavior can be assessed.
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Electrolitic Brain Lesions
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Electric brain lesions.
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Aspirations Lesion
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Part of the tissue is vacuumed, and then other structures are cut.
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Stimulation Methods
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Involve passing tiny currents across the tip of a permanently implanted electrode to activate neurons, and then assessing effects.
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Recording Methods
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Recording patterns of brain activity.
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Unit recording vs. Multiple-unit recording
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Unit recording: records activities of individual neurons.
Multiple-unit recording: records overall firing rate of many neurons around the electrode tip, to combine and provide a general measure of neural activity in the area. |
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EEG Recording
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Records moment-to-moment variations in the electrical potential between two large electrodes. This can be measures from electrodes places on scalp, therefore it is noninvasive.
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Agonist Pharmacological Methods
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Use of a drug that increases the neurotransmitter's effects.
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Antagonist Pharmacological Methods
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Use of a drug that reduces the neurotransmitter's effects.
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Steps in Neurotransmitter Action
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1) Synthesis of the neurotransmitter.
2) Storage in vesicles. 3) Breakdown in cytoplasm of any neurotransmitter that leaks from vesicle. 4) Exocytosis (release of neurotransmitters into synapse). 5) Released neurotransmitters bind with autoreceptors and stop more neurotransmitters from being released. 6) Activation of postsynaptic receptors. 7) Deactivation. |
