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197 Cards in this Set

  • Front
  • Back
How much does the human brain weigh?
1.3 kilograms
neuron
Pg 41. Neurons are cells that are specialized for the reception, conduction, and transmission of electrochemical signal that come in a variety of sizes
. Who was the man who played a key role in the emergence of biopsychology and wrote The Organization of Behaviors?
D. O . Hebb
Neuroanatomy
The study of the structure of the nervous system pg.8
neurophysiology
The study of the functions and activities of the nervous system pg. 8
neuroscience
The scientific study of the nervous system pg.5
phenotype
An organisms observable traits pg. 21
afferent nerves
Nerves in the somatic nervous system that carry sensory signals from the skin skeletal muscles, joints, eyes, ears, and so on to the central nervous system. Pg 37
efferent nerves
Nerves that carry motor signals from the central nervous system to the skeletal muscles pg 37
2 types of efferent nerves…
efferent and afferent
sympathetic nerves
autonomic motor nerves that project form the CNS in the lumbar and thoracic regions of the spinal cord. Stimulate organize and mobilize energy resources in threatening situations. Sympathetic changes are indicative of psychological arousal.
parasympathetic nerves
autonomic motor nerves that project from the brain and sacral region of the spinal cord. Act to conserve energy. Parasympathetic changes are indicative of psychological relaxation.
where is the PNS located
outside the skull and spine
What part of the PNS projects from only the cranial and sacral portions of the PNS?
parasympathetic nerves- pg 38
vagus nerve
The longest cranial nerves which contain motor and sensory fibers traveling to and from the gut. Pg. 39
meninges
A series of 3 protective membranes that cover the brain and spinal cord. 39
Sequence of the meninges from outside to inside
Dura Matter Meninx, Arachnoid meninx, Subarachnoid meninx. Pg. 39
How many ventricle are there in the brain?
4- the 2 lateral ventricles, 3rd vemtricle and the 4th ventricle
Where does the CSF circulate through?
It fills the Subarachnoid space, the central canal of the spinal cord, and the cerebral ventricles of the brain. It also supports and cushions the brain. Pg 39.
What does the cerebral aqueduct connect?
The 3rd and 4th ventricles pg 40 figure 2.4
What does the blood-brain barrier impede the passage of?
Impedes the passage of many toxic substances from the blood into the brain. BOOK pg.40
synapse
The gaps between adjacent neurons across which chemical signals are transmitted.
axon
The long, narrow process that projects from the cell body
dendrites
The short processes emanating from the cell body, which receives most of the synaptic contacts from other neurons
cell body
The metabolic center o the neurons; also called the soma
neurotransmitter
Molecules that are released from active neurons and influence the acridity of neuron and influence the activity of other cells
Where is most of neurons DNA?
In the nucleolus of the cell body
Where are most of the synaptic vesicles?
terminal buttons
Multipolar neurons (pic. BOOK pg 43)
A neuron with more than two processes extending from its cell body
endoplastic reticulum
System of folded membranes on the cell body; rough portions play a role in the synthesis of proteins; smooth portions play a role in the synthesis fats.
axons
The long, narrow process that projects from the cell body
ganglion
:Clusters of cells in the PNS
nuclei
Clusters of cells in the CNS
interneurons
Neurons with short axon or no axon at all
Tracts are to the nuclei as nerves are to what?
ganglion
myelin
A fatty insulating substance, increase the speed and efficiency of axonal conduction
in the CNS axons are myelinated by
Oligodendrocytes- send out extensions that wrap around the axons of some neurons of the CNS.
purpose of myelination
Keep the surviving neurons myelinated with glial cells.
schwann cells
Guide axonal regeneration (re growth) after damage in the PNS
astrocytes
Largest glial cells
microglia
Glial cell that engulf cellular debris
Golgi stain colors neuron what color
black
What is the cresyl violet stain used for or designed to do?
Used in the nissal stain and it penetrates all cells on a slide
What is best to use to study the fine inner details of the neuron?
electron microscopy
Back of head is?
posterior
Top of a dogs head is?
dorsal
The tip of the nose is?
interior and medial
The nose of a rat is?
anterior
anterior
:Toward the nose
posterior
Towards the tail (rostral, caludal)
dorsal
Towards the surface of the back or the top of head
ventral
:Toward the surface of the chest or the bottom of the head
medial
:Towards the midline of the body
lateral
Away from the midline towards the body’s lateral surface
superior
Towards the top of the primate head
inferior
Toward the bottom of the primate head or brain
proximal
:Close, closer to the CNS
distal
Far, Further from the CNS
horizontal sections
Any slice of brain tissue cut in a place that is parallel to the top of the brain
saggital sections
Any sliced of brain tissue cut in a place that is parallel to the side of the brain.
Which part of the diencephalon controls the pituitary?
Hypothalamus. It is located just below the anterior thalamus. It plays an important role in the regulation of several motivated behaviors. It excerpts effects in part by regulating the release of hormones from the pituitary gland.
adrenal cortex
The outer layer of the adrenal gland: it releases hormones that regulate energy, metabolism, mineral balance, and reproductive behavior.
adrenal medulla
The core of the adrenal gland; it is activated by the sympathetic nervous system, and in turn it secretes hormones whose effects are similar to those of the sympathetic nervous system.
autonomic nervous system
The division of the peripheral nervous system that participates in the regulation of the body’s internal environment; it conducts sensory signals to the CNS from receptors in internal organs, and motor signals from the CNS back to the same internal organs.
brain
The part of the CNS that is located in the skull.
central nervous system
The part of the vertebrate nervous system that is located within the skull and spine.
cervical region
The section of the spine that provides the flexible framework of the neck or cervix.
dorsal roots
The 31 pairs of sensory nerves that enter the spinal cord; they enter the spinal cord’s dorsal surface.
gonads
The sex glands (i.e. ovaries in women and testes in men); they release hormones that influence both the development of female and male reproductive behavior of adult.
hypothalamus
The brain structure from which the pituitary is suspended; it secretes releasing hormones, which stimulate the release of tropic hormones from the pituitary.
lumbar region
The section of the spine that supports the small of the back.
parasympathetic nervous system
One of the two motor divisions of the autonomic nervous system; it tends to conserve energy during periods of quiescence; parasympathetic nerves project from the brain and from the sacral region of the spinal cord.
peripheral nervous system
: The part of the vertebrate nervous system that is located outside the skull and spine.
pituitary gland
The gland that hangs from the hypothalamus; because it releases tropic hormones, it is often referred to as the master gland.
sacral region
The section of the spine to which the bones of the pelvis are attached.
soamtic nervous system
The division of the peripheral nervous system that interacts with the external environment; it conducts sensory signals to the CNS from external receptors and receptors in joints and skeletal muscles, and it conducts motor signals from the CNS to skeletal muscles.
spinal cord
The part of the CNS that is located in the spine.
spinal gray matter
The H-shaped area of gray nervous tissue in the spinal core of the spinal cord.
sympathetic nervous system
One of the two motor divisions of the autonomic nervous system; it tends to mobilize energy resources during periods of threat; sympathetic nerves project from the thoracic and lumbar regions of the spinal cord.
thoracic region
The section of the spine to which the ribs are attached.
ventral roots
: The 31 pairs of motor nerves that exit the spinal cord; they project from the spinal cord’s ventral surface.
contralateral
: Projecting from one side of the body to the other.
ipsilateral
On the same side of the body.
astrocytes
Large star-shaped glial cells whose many projections terminate on other astrocytes, blood vessels, and neurons.
axon
The single long fiber that extends from a neurons cell body; its function is to conduct neural signals from the cell body to other parts of the nervous system
axon hillock
The cone shaped structure between the cell body and axon.
buttons
The button like terminal endings of the axon branches.
cell body
the metabolic center of the neuron; also called the soma.
cell membrane
: the semi-permeable membrane tat encloses the cytoplasm of neurons and other cells; the wall of the cell.
cytoplasm
the clear inner fluid of neurons and other cells
dendrites
: the short bushy fibers that branch out from the cell body; they constitute the major signal-receiving area of the neuron.
dendritic spines
tiny protuberances on dendrites that are the location of many dendritic synapses.
G-protein
A protein molecule that is activated inside a neuron when a neurotransmitter molecule binds to the receptor on its associated signal protein.
golgi appartaus
systems of smooth plate-shaped membranous sacs in the cytoplasm of cells; they package proteins and other molecules in small membrane sacs
ion channels
specialized pores in the neuron cell membrane through which ions can pass; some are chemical gated and some are voltage gated.
ionotropic receptors
receptors that are associated with ion channels; when activated they typically induce rapid brief signals in the neuron by opening or closing the ion channel.
macroglia
large glial cells such as oligodendrocytes, Schwann cells, and Astrocytes.
metabotropic receptors
receptors that are associated with signal proteins and g proteins; when activated they typically induce slow, long-lasting changes in the neuron by changing its internal chemistry.
microglia
small glial cells; their function is phagocytosis.
microtubules
Fine tubes that course through the neural cytoplasm; they provide routes for the transport of molecules within neurons.
mitochondria
: structures of the cytoplasm that play a role in its respiration and in its production and use of energy.
neurofilaments
fine thread-like structures that form a matrix in the cytoplasm; they provide support for the cell membrane and maintain the shape of the neuron.
neurotransmitter molecules
molecules that are released from the buttons of active neurons and influence the activity of other cells.
nodes of ranvier
: the gaps between adjacent glial segments on a myelinated axon
nucleus
the large spherical structure in the cytoplasm of every cell; it contains the genetic material; in neurons it is located in the cell body.
oligodendrocytes
Glial cells that myelinate CNS axons
postsynaptic membrane
the section of the cell membrane of a postsynaptic neuron that is adjacent to the synaptic cleft; the postsynaptic membrane contains postsynaptic receptors.
presynaptic membrane
: the section of the button membrane that is adjacent to the synaptic cleft; the site from which neurotransmitter molecules are released into a synapse.
receptive area
: the dendrites and cell body of a neuron; the area of a neuron that receives most of its synaptic input.
receptors
molecules in the neuron cell membrane to which neurotransmitter molecules bind in key in lock fashion and, in doing so, induce signals in the neuron.
ribosomes
the structures on which each cells protein are synthesized; ribosomes are attached to the rough endoplasmic reticulum.
endoplasmic reticulum
the system of rough plateshaped membranous sacs in the cytoplasm of cells; its rough appearance stems from the fact that it is covered with ribosomes in neurons it is located in the cell body.
schwann cells
glial cells that myelinate PNS axons.
signal proteins
: proteins that snake back and forth through the cell membrane seven times and conduct signals into the neuron when their associated receptors are activated.
synapse
the narrow cleft between a terminal button on of neuron and the receptive membrane of another
synaptic vesicles
: membrane sacs that store neurotransmitter molecules ready for release near the pre-synaptic membrane; they are manufactured by the Golgi apparatus.
anterior commisure
The commissure that is located just inferior to the anterior tip of the corpus Callosum; a major route of communication between the left and right temporal lobes.
arachnoid membrane
The middle menynx; it has the texture of a gauze-like spider web.
brain stem
: The Central Neural Stem on which the two cerebral hemispheres sit; many brain stem structures play key roles in the regulation of body’s inner environment.
central canal
The cerebrospinal-fluid-filled internal space that runs the length of the spinal cord.
cerebral aqueduct
The narrow channel that connects the third and fourth ventricle; most of it is located in the Mesencephalon.
cerebral hemisphere
Two large neural structures that sit atop the vertebrate brain stem, one on the left and one on the right; they meditate complex psychological processes.
cerebrospinal fluid
The fluid that fills both the subarachnoid space and the hollow core of the brain and spinal cord; it supports, nourishes, and cushions the CNS.
corpus callosum
By far the largest cerebral commissure; it is composed of about 200 million axons.
diencephalon
The region of the brain between the Telencephalon and the Mesencephalon; one of the two divisions of the forebrain (the other is the Telencephalon); the most anterior region of the brain stem.
dura mater
The outermost and toughest of the three meninges.
fourth ventricle
The cerebral ventricle of the metencephalon; it connects the cerebral aqueduct and the central canal.
ganglia
Structures of the PNS that are composed largely of neural cell bodies; their function is the local analysis of neural signals (singular ganglion).
lateral ventricles
The ventricle of the left and right cerebral hemispheres; they are the largest of the four cerebral ventricles
longitudinal fissures
: The deep midline chasm between the two cerebral hemispheres.
massa intermedia
The commissure that is located in the middle of the third ventricle; it is a route of communication between the left and right diencephalon, which is largely separated by the third ventricle.
mesencephalon
: The midbrain; the region of the brain stem between the diencephalon and the metencephalon.
metencephalon
: The region of the brain stem between the Mesencephalon and the lyelencephalon; one of the two divisions of the hindbrain (the other is the Myelencephalon).
meyelincephalon
: The most posterior region of the brain, the area of the brain stem between the metencephalon and the spinal cord; one of the two divisions of the hindbrain ( the other is the metencephalon).
nerves
Structures of the PNS that are composed largely of axons; their function is to conduct action potentials from one part of the PNS to another.
nuclei
Structures of the CNS that are composed largely of neural cell bodies; their function is the local analysis of neural signals. (Singular: nucleus)
olfactory nerves
: The first pair of cranial nerves; they carry sensory signals from the olfactory bulbs to the brain.
optic nerves
: The second pair of cranial nerves; they carry sensory signals from the visual receptors of the eyes to the brain.
pia mater
the innermost and most delicate of the three meninges; it adheres to the surface of the CNS.
subarachnoid spave
The space between the arachnoid membrane and the pia mater; it contains cerebrospinal fluid, the weblike processes of the arachnoid layer, and many blood vessels.
telencephalon
The cerebral hemispheres, one of the two divisions of the forebrain (the other is the diencephalon).
third ventricle
The cerebral ventricle of the diencephalon; it is a vertical sheet-shaped chamber that lies along the midline.
tracts
: Structures of the CNS that are composed largely of axons; their function is to conduct action potentials from one part of the CNS to another.
trigeminal nerves
: The fifth pair of cranial nerves, each of which has three major branches; they conduct motor signals from the brain to the muscles involved in chewing, and sensory signals from the same muscles and from other parts of the face to the brain.
vagus nerves
The tenth and longest pair of cranial nerves; they conduct signals to and from the organs of the gut (e.g., to and from the heart, liver, and stomach).
vestibulocohlear nerves
The eighth pair of cranial nerves, which carry sensory signas from the inner ear to brain; one branch carries sensory signals from the organs of balance (i.e., from the vestibular organs), and the other branch carries sensory signals from organs of hearing (i.e., from the cochlea).
how many ventral and dorsal roots are there in the body?
31
what is myelencephalon often called
myelin
where is the reticular formation located?
in the central core of the brain stem
what parts make up the diencephalon
thalamus and hypothalamus
4 lobes
frontal parietal occipital temporal
hippocampus
role in memory. Part of the limbic system. Located at medial edge of the cerebral cortex. Hippocampus means “sea horse” (because of its shape).
limbic system
Plays a role in motivated behaviors: fleeing, feeding, fighting, and sexual behavior. A circuit of midline brain structures that circle the thalamus. (thalamus means “ring”). Circuit of brain structures include the: cingulated cortex, fornix, hippocampus, amygdala, mammilary body, and the septum. See figure 2.27 on p 57.
fornix
major tract of the limbic system. Fornix means “arc”.
amygdala
an almond shaped nucleus in the anterior temporal lobe. Amygdala means “almond”. The amygdala is a part of the limbic system and the basal ganglia.
septum
the midline nucleus located at the anterior tip of the cingulate cortex.
basal ganglia
a group of subcortical structures with a role in voluntary movement. See figure 2.28 on p 57. This group includes the amygdala, caudate, putamen, and the globus pallidus
absolute refractory period
): a brief period, usually 1-2 milliseconds, after an action potential has fired in which it is impossible for another action potential to fire in the same neuron.
relative refractory period
): a period after an absolute refractory period in which it is possible to initiate a new action potential, but doing so requires higher than normal stimulation.
resting potential
the steady membrane potential of a neuron at rest, usually -70 mV. (membrane potential – the difference in electrical charges inside and outside of a cell.)
microelectrodes
extremely fine recording electrodes used for intercellular recording (to measure electrical charges inside and outside a cell).
ions
): positively or negatively charged particles. (for this class context we mostly deal with sodium, potassium, or chloride).
ion channels
specialized pores in neural membranes through which specific ions pass.
sodium potasium pumps. 66-67
): pumping mechanisms which pump many positively charged sodium (NA+) outside the cell and fewer positively charged potassium (K+) ions inside the cell. (Large quantities of sodium outside the cell majorly contribute to resting potential).
depolarize 68
to decrease the resting membrane potential. (reduce the negative membrane potential from -70mV to -67 mV).
HYPERPOLARIZE
(68): to increase the resting membrane potential. (to increase the negative membrane potential from -70 mV to -72 mV).
axon hillock
the conical structure at the junction between the cell body and the axon. (It used to be thought that action potentials started here, but it has been found that APs actually begin in the adjacent first section of the axon when the sum of depolarizations and hyperpolarizations reaching this first section of the axon reach the threshold of excitation.)
threshold of excitation
(69): The level of depolarization required to generate an action potention (AP), usually -65 mV.
action potential
(69): a massive, momentary, all-or-none reversal of the membrane from about -70 mV to +50 mV, lasting for only about 1 millisecond.
voltage activated ion channels
(71): ion channels that open or close in response to changes in the level of the membrane potential.
nodes of ranvier
73): the gaps between adjacent myelinated segments in myelinated axons.
velocity of axonal conduction
(73): the velocity (speed) of conduction depends on 2 properties: (1) conduction = faster in axons with larger diameters. & (2) conduction = faster in myelinated axons.
ionotropic receptors
-:Are those receptors that are associated with ligand-activated ion channels.
metabotropic receptors
Are those receptors that are associated with signal proteins and G proteins (guanosine-triphosphate-sensitive proteins).
reuptake
Drawing back the neurotransmitter into the presynaptic terminal. Reuptake is the more common of the two deactivating mechanisms
enzymatic degredation
chemical breakdown of neurotransmitter
aminp acids
Building blocks of protein. (The four most widely acknowledged amino acid neurotransmitters are glutamate, aspartate, glycine, and gamma-aminobutyric acid).
golgi complex
:A system of membranes that packages molecules in vesicles.
Where are protein neurotransmitters synthesized in the cell body?
Small-molecule neurotransmitters are typically synthesized in the cytoplasm and the terminal button and packaged there in synaptic vesicles.
autoreceptors
Are metabotropic receptors that have two unconventional characteristics: They bind to their neuron’s own neurotransmitter molecules; and they are located on the presynaptic, rather than the postsynaptic, membrane. pg 78
What are neurotransmitters deactivated by after release? Pg 78
Reuptake or enzymatic degradation (reuptake is more common)
What neurotransmitter is considered to be the most prevalent? Pg 79
Glutamate is the most prevalent excitatory neurotransmitter in the mammalian CNS; GABA is the most prevalent inhibitory neurotransmitter.
Monoamines- pg 79
Are another class of small-molecule neurotransmitters. Each is synthesized from a single amino acid-hence the name monoamine (one amine).
Catecholamines- pg 79 (definition in glossary)
A group of small-molecule neurotransmitters (dopamine, norepinephrine, and epinephrine).
What is synthesized from tyrosine?
Pg 79
Dopamine, norepinephrine, and epinephrine.
What do adrenergic neurons release?
They release epinephrine (pg 80 )
bregma
The point on top of the skull where two of the major sutures intersect (the seams in the skull)
sterotaxic surgery
: Experimental devices that are precisely positioned in the depths of the brain ( pg 82 )
suction lesion
: The easy way to explain is to see figure 3.15 (pg84)
aspiration legion
The surgeon deftly draws away the target tissue through the fine tip of glass pipette attached to a vacuum pump. (pg 85 ) again see figure 3.15
antagonists
Drugs that reduce (pg 85)
agonists
Drugs that increase (pg 85)
cocaine
Potent agonist (increases activity of both dopamine and norepinphrene by blocking their uptake synapses (pg 89)
Curare x- ray techniques that locate Vascular abnormalities in the brain?
Cerebral angiography (pg 89)
What is the most detailed 3-D view of the brain is done by what?
Structural MRI ( pg 90)
How is the CT scan presented?
Horizontal sections of the brain (pg 90 )
What do PET scans do?
Provide images rather than structure (pg 90)