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37 Cards in this Set
- Front
- Back
where is interstitial fluids located?
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between cells and vessels
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what is the formula for (pressure) aka blood pressure?
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flow x resistance
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what does blood viscosity mean?
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thickness
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what makes resistance?
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small constricted blood vessels make high pressure
big dilated blood vessels makes low pressure |
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sympathetic nervous system
what catacholamines are produced? |
epi and norepi
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what does alpha do?
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vasoconstrict arms and legs
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what does beta do?
B1? B2? |
B1- increases heart rate (receptor in the heart)
B2- bronchodilates (receptor in lungs) |
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what does the RAA system do in fight or flight?
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angiotensin 1 converted to angio II which is a potent vasoconstrictor
aldosterone- secreted which is an antidiuretic hormone therefore retains sodium and water urine becomes more concentrated therefore thicker less sodium in urine and more potassium in urine |
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Shock can be acute
widespread or impaired which means? |
sudden
whole body tissue perfusion (blood can't get there) cell metabolism (cells have no energy) or hemodynamics |
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S and S for all shocks?
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SBP <90
Hr is either brady or tachy altered mental status narrow blood pressures- ex. 70/50 |
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what is the formula for pulse pressure?
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systolic - diastolic = pulse pressure
normal *40* d/t 120 - 80 = 40 |
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what are the four stages of shock?
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initial
compensatory progresive refractory |
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what happens in initial stage of shock?
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decreased Cardiac output
impaired tissue perfusion (check 02 sats) lactic acidosis (can be determined by blood test) |
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what happens in compensatory stage of shock?
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SNS
inc HR and contractability artery and venous vasoconstriciton shunt to vital organs RAA stim ant pit- ADTH adrenal medulla- release epi and norepi Chemical- hyperventilate |
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what happens in progressive shock?
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Na-K pump fails
cell energy production fails digestive organelles swell |
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what happens in refractory shock?
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unresponsive to therapy
MODS (multi organ dysfunction syndrome) ultimately death regardless of cause d/t ineffective tissue perfusion |
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cardiovascular patho to all shocks?
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mycardial depressant factor (MDF) excreted from the pancreas d/t lack of blood flow to the pancreas and other organs (wants to slow the heart to conserve energy)
lactic acidosis |
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neurologic patho to all shocks?
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can't regulate temp, HR, Resp, etc. d/t the SNS failing
Brain not getting enough blood Vessels dilate leads to pooling of blood into the lower extremities increased cap. permeability therefore 3rd spacing small blood clots |
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Hematologic patho to all shocks?
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decreased BP
hypoxemia acidosis (retaining Co2) stasis of cap blood DIC (disseminated intravascular coagulation)- clot then bleed out |
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pulmonary patho to all shocks?
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increased pulmonary cap permeability
micro emboli vasoconstriction resp. failure and acture resp. distress (ARDS) |
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renal patho to all shocks?
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vasoconstriction and hypofusion
acute tubular necrosis (need to monitor kidney function) |
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gastrointestinal patho to all shocks?
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vasoconstriction- gut starts leaking out therefore gram negative bacteria in the GI tract
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what is cardiogenic shock?
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failure of heart to pump
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what causes cardiogenic shock?
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most commonly caused by MI
**high mortality** |
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patho of cardiogenic shock?
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decreased cardiac output
injured ventricles can't push blood so stroke volume is decreased poor emptying d/t not being able to push everythin gout increased pulmonary pressure d/t things backing up pulmonary edema dec oxygenation (can't transfer Co2 and O2 through fluids in the lungs) |
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left S and S of cardiogenic shock?
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crackles in lungs
dec peripheral pulses dec O2 sats altered mental status hyperventilation acidosis dec renal output |
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right S and S of cardiogenic shock?
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edema in LE
JVD ascites hepatomegaly inc central venous pressure |
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cardiogenic management?
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intraaortic balloon
+ inotropes (digoxin) vasodilators (nitro) diuretics antidysrhythmics ventricular assist device |
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when is ventricular assist device used?
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when waiting for a heart transplant
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what are complications of intraaortic balloon?
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if slips too low it will cut off renal flow
if too high it will cut off blood flow through the subclavian and carotid arteries |
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when intraaortic balloon is inflated, the aortic valve is?
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closed
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hypovolemic shock?
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too low blood volume
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causes of hypovolemic shock?
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absolute loss
relative loss |
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absolute loss?
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bleeding out on the floor, can see the blood
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relative loss
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intravascular to extravascular
3rd spacing can't see the blood loss from the blood vessels |
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patho of hypovolemic shock?
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everything decresed
intravascular volume venous return stroke volume cardiac output tissue perfusion cellular metabolism |
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what is the intial sign of hypovolemic shock?
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resp. alkalosis, because of hyperventilation and blowing off too much CO2
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