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21 Cards in this Set
- Front
- Back
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Recessive- Somewhere between1st and 2nd chromosome. One in 20 white americans carries the recessive allele._________ results in the formation and accumulation of thick mucas in the lungs an digestive track.
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Cystic Fibrosis
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Recessive disorder- In _______, a recessive allele results in the absence of an enzyme that normally breaks down a lipid produced and stored in tissues of the central nervous system.
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Tay Sachs
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Recessive disorder that results from the absence of an enzyme that converts one amino acid, Phenolalanine, to a different amino acid , Thyrosine.
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Phenylketonuria
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Lethal genetic disorder caused by a rare dominant allele. It results a break down of certain areas of the brain.
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Huntington's Disease
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~Heterois intermediate between those of the 2 homo. (averages)
~Everything is capitol because nothing is recessive. |
Incomplete Dominance
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Both alleles are expressed equally
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Codominance
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~Trait Controlled by more than 2 alleles.
~Study Whole Population ~Depends on what you enherit ~Over a whole population there are many different colors/choices. |
Multiple Alleles
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Traits controlled by genes on sex-chromosomes.
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Sex-Linked Traits
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~Put allele directly on x-Chromosome
~23rd pair- Sex Chromosome |
Sex Linked Inheritance
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~Continus range of a phentotype
~3 genes control height and 2 alleles control plant weight. |
Polygenic Inheritance
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~Pretty Common
~Autosomal Recessive Disorder ~Biconcave Disc ~Hemogloban carry's oxygen to tissue, gives oxygen off @ tissues, picks up carbon dioxide & takes to lungs to breath ~People have shorter life spans, anemic, and achy joints ~No treatment |
Sickle Cell Anemia
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A protein on the Red Blood Cell
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Anitgen
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In Liquid part (serium/plasma)
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Antibodies
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Blood Doesnt Clot
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Hemophelia
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Abnormal numbers of chromosomes
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Aneuploidy
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Breed for things we like
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Selective Breeding
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Prove animal had been breed with a known homozygous recessive animal.
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Test Cross
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3 steps to make a trangenic organism:
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1. Find the foreign DNA to be used
2. Attach the DNA to a vector that will introduce the DNA segment to the host 3. Transfer the DNA vehicle into the host organism |
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How We Do it?
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1. Restriction enzyme cut the DNA at a specefic nucleotide sequence.
2. New piece is introduced by a vector to carry the pieces to Host Cell. 3. Insert into another cell & the DNA rejoins. |
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Application of this knowledge to help our world:
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1. Industry- break downs oil pollutants
2. medicine- human disease treatment and transgenic animals to study resistance. 3. Agriculture- Bigger, better, more. |
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Why do we want to know about the Human Genome Project?
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1. Diagnosis of Genetic disorder or disease
2. Gene therapy 3. DNA Fingerprinting |
