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11 Cards in this Set

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  • Back

What is cellular respiration and what are its 3 stages?

- Harvests energy from glucose in the presence of oxygen


1. Glycolysis: breaks down glucose into 2 pyruvate molecules


2. Kreb's Cycle/Citric Acid Cycle/TCA Cycle: completes breakdown of glucose


3. Oxidative phosphorylation: accounts for most of the ATP synthesis

Fermentation

- Harvests energy from glucose in the absence of oxygen

Redox reactions


- what happens in oxidation?


- what happens in oxidation?


- define reducing agent and oxidizing agent

- aka oxidation-reduction reactions


- oxidation: substance loses an electron (LEO)


- reduction: substance gains an electron (GER)


- reducing agent: electron donor


- oxidizing agent: electron acceptor

Give a brief summary of what happens during cellular respiration

- Glucose is oxidized (loses electrons/Hs) and yields CO2


- O2 is reduced (gains electrons/Hs) and yields H20


- The transfer of electrons releases energy stored in organic molecules, which makes ATP

Why do animals need to breathe oxygen to live?

- it is the giant electronegative "catcher's mitt" of the electron transport chain

3 things that mess with cellular respiration

1. arsenic: inhibits succinate dehydrogenase in Kreb's cycle


2. cyanide: blocks Complex IV by binding irreversibly to Cytochrome Oxidase


3. DNP (diet drug in the 50s) makes inner membrane of mitochondria "leaky, allows H+ to flow back into the matrix without going through ATP synthase

What are the two different ways to make ATP in cellular respiration?

1. substrate-level phosphorylation (ATP produced from phosphorylated substrate)


2. oxidative phosphorylation (ATP production from oxidation-reduction reactions)

What are the 4 steps of oxidative phosphorylation?

1. a rotor spins clockwise when H+ flows past


2. a stator holds the knob stationary


3. a stalk extending into the knob spins, activating catalytic sites


4. three catalytic sites in the stationary knob join Pi + ADP to produce ATP

What are the steps in substrate-level phosphorylation?

sfsa

Hans Adolf Krebs

discovered citric acid cycle

Fritz Albert Lipmann

discovered coenzyme A