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109 Cards in this Set
- Front
- Back
reproduction of cells
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cell division
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the life of a cell from the time it is first formed from a dividing parent cell until its own division into two cells
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cell cycle
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a cell's endowment of DNA, its genetic information
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genome
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packaged DNA
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chromosomes
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all body cells except the reproductive cells
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somatic cells
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reproductive cells (sperm and eggs)
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gametes
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a complex of DNA and associated protein molecules
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chromatin
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two chromatids, each containing an identical DNA molecule, that are attached to each other initially
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sister chromatids
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a specialized region where the two chromatids are most closely attached
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centromere
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the division of the nucleus, resulting in two, identical daughter cells
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mitosis
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cell division that results in 4, nonidentical daughter cells
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meiosis
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the phase which included both mitosis and cytokinesis, and is usually the shortest part of the cell cycle
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mitotic (M) phase
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the stage in which the cell grow and copies its chromosomes in preparation for cell division
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interphase
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the phase in which chromosomes are duplicated
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S phase
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a structure consisting of fibers made of microtubules and associated protiens
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mitotic spindle
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a subcellular region containing material that functions throughout the cell cycle to organize the cell's microtubules
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centrosome
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a radial array of short microtubules, extends from each centrosome
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aster
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a structure of proteins associated with specific sections of chromosomal DNA at the centromere
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kinetochore
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the imaginary plane midway between the spindle's two poles where the centromeres of all the duplicated chromosomes line up
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metaphase plate
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a shallow groove in the cell surface near the old metaphase plate
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cleavage furrow
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produced by vesicles derived from the Golgi apparatus move along microtubules to the middle of the cell, where they coalesce
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cell wall
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a type of cell division that involves asexual reproduction of single-celled eukaryotes
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binary fission
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a specific place on the chromosome where the chromosome begins to replicate
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origin of replication
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a cyclically operating set of molecules in the cell that both triggers and coordinates key events in the cell cycle
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cell cycle control system
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a control point where stop and go-ahead signals can regulate the cell cycle
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checkpoint
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a nondividing state
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G-zero phase
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enzymes that activate or inactivate other proteins by phosphorylating them
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protein kinases
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a protein that gets its name from its cyclically fluctuating concentration in the cell
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cyclin
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kinases that must be attached to cyclin to be active
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cyclin-dependent kinases (Cdks)
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the complex that triggers the cell's passage past the G2 checkpoint into M phase
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maturation-promoting factor/ M-phase promoting factor/ MPF
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a protein released by certain cells that stimulates other cells to divide
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growth factor
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a phenomenon in which crowded cell stop dividing
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density-dependent inhibition
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a phenomenon in which cells must be attached to a substratum, such as the inside of a culture jar or the extracellular matrix of tissue, to divide
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anchorage dependence
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the process that converts a normal cell to a cancer cell
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transformation
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a lump in which the abnormal cells remain at the original cell
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benign tumor
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a lump that becomes invasive enough to impair the functions of one or more organs
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malignant tumor
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the spread of cancer cells to locations distant from their original site
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metastasis
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the transmission of traits from one generation to the next
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heredity
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hereditary units
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genes
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reproductive cells in animals and plants
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gametes
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a single individual is the sole parent and passes copies of all its genes to its offspring
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asexual reproduction
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two parents give rise to offspring that have unique combinations of genes inherited from the two parents
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sexual reproduction
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the generation-to-generation sequence of stages in the reproductive history of an organism, from conception to production of its own offspring
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life cycle
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any cell other than those involved in gamete formation
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somatic cell
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an ordered display of chromosomes arranges in pairs, starting with the longest chromosomes
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karyotype
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the two chromosomes composing a pair that have the same length, centromere position, and staining pattern
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homologous chromosomes
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the X and Y chromosomes
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sex chromosomes
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chromosomes other than the sex chromosomes
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autosomes
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any cell with two chromosome sets
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diploid cell
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any cell with a single chromosome set
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haploid cell
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the union of gemetes, culminating in fusion of their nuclei
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fertilization
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the result of a fertilized egg
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zygote
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a type of life cycle that included both diploid and haploid stages that are multicellular
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alternation of generations
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the multicellular diploid stage in alternation of generations
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sporophyte
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Meiosis in a sporophyte produces haploid cells called:
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spores
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mitotic division generating a multicellular haploid stage in alternation of generations
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gametophyte
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stage that produces a diploid cell with replicated chromosomes
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meiosis 1
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stage that produces haploid cells with unreplicated chromosomes
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meiosis 2
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the process in which replicated homologs pair up and become physically connected along their lengths by a zipper-like protein structure
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synapsis
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genetic rearrangement between nonsister chromatids
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crossing over
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X-shaped region where nonsister chromatids remain connected while being pulled slightly apart
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chiasma
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individual chromosomes that carry genes derived from two different parents
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recombinant chromosomes
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a heritable feature that varies among individuals
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character
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varieties that, over many generations of self-pollination, produce on the same variety as the parent plant
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true-breeding
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the mating of two true-breeding varieties
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hybridization
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the true-breeding parents in a hybridization cross
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P generation
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the hybrid offspring of the P generation
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F1 generation
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the offspring resulting in F1 hybrids that self-pollinate
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F2 generation
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the two alleles for a heritable character segregate during gamete formation and end up in different gametes
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law of segregation
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a diagrammatic device for predicting the allele composition of offspring from a cross between individuals of known genetic makeup
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Punnett square
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an organism that has a pair of identical alleles for a character
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homozygous
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an organism that has two different alleles for a gene
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heterozygous
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an organism's appearance or observable traits
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phenotype
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an organism's genetic makeup
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genotype
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breeding an organism of unknown genotype with a recessive homozygote
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testcross
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heterozygous for one character
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monohybrid
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individuals heterozygous for two characters
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dihybrid
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each pair of alleles segregates independently of each other pair of alleles during gamete formation
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law of independent assortment
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phenomenon where the F1 offspring always looked like one of the two parental varieties because one allele in a pair shows ___________ over the other
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complete dominance
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phenomenon where neither allele is completely dominant, and the F1 hybrids have a phenotype somewhere between those of the two parental varieties
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incomplete dominance
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phenomenon in which the two alleles both affect the phenotype in separate, distinguishable ways
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codominance
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when one gene has multiple phenotypic effects
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pleiotropy
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a gene at one locus alters the phenotypic expression of a gene at a second locus
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epistasis
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characters that vary in the population along a continuum (in gradations)
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quantitative characters
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an additive effect of two or more genes on a single phenotypic character
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polygenic inheritance
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phenotypic range for a genotype
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norm of reaction
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a family tree describing the certain traits of parents and children across generations
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pedigree
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heterozygotes that can transmit the recessive allele to their offspring
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carriers
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technique of extracting amniotic fluid to perform genetic tests
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amniocentesis
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technique of extracting a sample of tissue in the placenta to perform genetic tests
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chorionic villus sampling (CVS)
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the theory that Mendelian genes have specific loci along chromosomes, and it is the chromosomes that undergo segregation and independent assortment
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chromosome theory of inheritance
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the phenotype for a character most commonly observed in natural populations
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wild type
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a gene located on either sex chromosome
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sex-linked gene
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disease in males characterized by a progressive weakening of the muscles and lack of coordination
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Duchenne muscular dystrophy
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a sex-linked recessive disorder defined by the absence of one or more of the proteins required for blood clotting
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hemophilia
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genes located on the same chromosome that tend to be inherited together in genetic crosses
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linked genes
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offspring that inherit a phenotype that matches one of the parental phenotypes
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parental types
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offspring with a phenotype combination unlike either parent
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recombinant types (recombinants)
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genetic map based on recombination frequencies
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linkage map
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the distance between genes
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map units (centimorgans)
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when the members of a pair of homologous chromosomes do not move apart properly during meiosis 1 or sister chromatids fails to separate during meiosis 2
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nondisjunction
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condition in which a zygote has an abnormal number of a chromosome
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aneuploidy
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an aneuploidic zygote with 2n-1 number of chromosomes
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monosomic
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an aneuploidic zygote with 2n+1 number of chromosomes
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trisomic
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condition in which an organism has more than two complete chromosome sets in all somatic cells
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polyploidy
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when a chromosomal fragment is lost
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deletion
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when a chromosomal fragment reattaches to the original chromosome but in the reverse orientation
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inversion
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when a fragment from one chromosome joins a different nonhomlogous chromosome
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translocation
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aneuploidy condition resulting from an extra chromosome 21, often called trisomy 21
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Down syndrome
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