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34 Cards in this Set

  • Front
  • Back
long bone
longer than wide, serve as levers

ex: humerus
short bones
equal in length and width
glide across one another

ex: carpals
flat bones
encircle; protection for organs, muscle attachment

ex: scapula/hip bones
irregular bones
don't fit into other categories

ex: sphenoid
medullary cavity
cylindrical part of long bone, houses bone marrow
diaphysis
shaft of bone
epiphysis
head of bone
periosteum
outer sheath covering compact bone with 2 layers

Outer: fibrous layer of collagen
Inner: osteogenic layer of bone-forming cells
endosteum
inner lining of bone, contains bone cells
epiphyseal plate
"growth zone" of hyaline cartilage that eventually calcifies
diploe
spongy bone of cranium
osteogenic cells
bone cells that give rise to osteocytes and osteoblasts
osteoblasts
nonmitotic bone cells that form bone; deposit soft matter of bone matrix (that eventually calcifies)
osteocytes
osteoblasts that have become trapped in the matrix they deposited; are "strain sensors"

-reside in lacunae
-connected by canaliculi
-also connected by gap junctions to spread nutrients
osteoclasts
bone-dissolving cells, arise from blood stem cells, have multiple nuclei and ruffled border to increase bone resabsortion efficiency
rickets
when the bone composite lacks enough ceramic material and bones are too 'bendy'
osteogenis imperfecta
"brittle bone disease" bone composite lacks protein and are too brittle
concentric lamellae
onionlike layers of compact bone around a central canal
perforating (Volkman) canals
passageways that connect osteons
collagen fibers in compact bone
"corkscrew" down the lamellae of osteons to increase strength
Interstitial lamellae
irregular regions that are the remains of old osteons that broke down as the bone grew and underwent remodeling
calcitriol
Raises blood calcium levels, most active form of vitamin D
hydroxyapatite
main ceramic component of bone
lamella
layer (of bone)
primary ossification center
area where blood vessels invade bony collar in middle of former cartilage model, eventually becomes primary marrow cavity
metaphysic
region of transition at each end of primary marrow cavity

cartilage--bone
secondary ossification center
located at each epiphysis, formed when chondrocytes here enlarge and die and then blood vessels invade and give rise to bone-forming cells
ectopic ossification
when calcification occurs in areas it shouldn't
acid phosphatase
secreted by osteoblasts to dissolve collagen matrix
hypocalcemia
low blood calcium, causes spasms and tetany

corrected by PHT and Cacitriol (vitamin d)
hypercalcimia
fairly fair, excess of Calcium in the blood, causes muscles to be LESS excitable

-corrected by Calcitonin
Calcitonin
secreted by C cells of the thyroid gland, corrects hypercalcemia

-reduces osteoclast activity
-important role in children
-fast-acting
Parathyroid Hormone
raises blood calcium concentration; promote absortion by kidneys

-can both increase AND decrease bone mass
Calcitriol
Raises blood calcium as well as phosphate levels
-form of vitamin D