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86 Cards in this Set

  • Front
  • Back
Certain bones serve as the site of blood cell formation known as:
Hemopoiesis
Hemopoiesis occurs in:
red marrow of certain bones
Name given to red marrow in flat bones:
Dipole
Yellow marrow of bone contains:
Adipose Tissue
Forms outer walls of bones
Consists of osteons
solid and strong
deposited over spongy bone
Compact Bone
Found at ends ends of long bones and in the middle portion of most other bones
Consists of trabeculae
open spaces between trabeculae
Spongy Bone
Interconnected Bars of bone:
Trabeculae
4 Classifications of Bone
Long
Short
Flat
Irregular
Posses long axis with expanded ends
diaphysis(shaft)
epiphysis (expanded ends) - contains spongy bone inside
Long Bone
cube shaped
compact bone over spongy bone
wrist and ankle
Short Bone
Bones that form inside a tendon
(patella)
Sesamoid
relatively flat bone and may have curved surfaces,
compact bone over spongy bone
the spongy bone contains hematopoietic tissue
Flat
Unusual shapes that don't fit other categories
(vertebrae,sphenoid)
Irregular
Membranes of Bone 2
Periosteum
Endosteum
Dense irregular CT that covers outside of bone except at articular surfaces:
(very vascularized)
Periosteum
tufts of collagen fibers that anchor periosteum to underlying compact bone:
Sharpey's fibers
Bottom layer of periosteum that rests on top of the bone:
(also found in endosteum)
Osteogenic Layer of Periosteum
Oteogenic layer of periosteum contains 2 cells:
Osteoblasts and Osteoclasts
Covers the internal surfaces of bones:
(including trebeculae of spongy bone)
(areolar ct)
Endosteum
Shaft of long bone is called:
Diaphysis
Diaphysis is hollow and filled with:
adipose tissue (yellow marrow)
Top and bottom of long bone:
Epihysis
Epiphysis is filled with:
Spongy bone
You can find what cells in Epiphysis:
Hemopoetic Cells
Hemopoetic Cells are located:
Between Trabeculae
Loomen of diathesis is called:
Medullary Cavity
Compact bone is made of structural unit called:
Osteon
Canal through the middle of the osteon:
Central Canal
Concentric rings of osteons:
Lamela
Within the lamela there are cavities called:
Lacuna
Within the lacuna there are:
Osteocytes
Between the lacuna is the:
Bony Matrix (filled with calcium salts)
Tiny canals that connect the central canal to the osteocytes in the lacuna
Canaliculi
(Filled with interstitial fluid)
Compact bone is pierced by ____________ that go from the outside of bones to the inside to provide vascular supply and pass through the central canal of the ostenons
Perforating Canals
Bone forming cells:
Osteoblasts
(bone deposition)
Osteoblasts are found:
In osteogenic layer of
periostium
and
endostium
Osteoblasts make:
Osteoid
(Bony matrix)
How do calcium salts get into osteoids?
Calcium slats diffuse through capillary walls into the osteoid
Osteoblasts make:
osteons and trabeculi in spongy bone
Osteoblast traped in lacuna:
osteocyte
Maintain the health of the bony matrix:
Osteocytes
The breaking down of bone:
(bone resorption)
Osteoclasts
Osteoclasts are found:
In the osteogenic layer
(bottom portion of perioseum and endosteum on surface of bone)
Osteoclasts secrete an enzyme that breaks down collagen in the bony matrix:
collagenase
How does osteoclast work:
Secrete an acid that brings Ca salts into a solution which then wash out of bones
When bone shapes itself as it grows and when new bone is created during repair process:
Bone Remodeling
Bone Remodeling Includes:
Osteoblastic Deposition
Osteoclastic Resorption
Law that states bone will increase or decrease its strength in response to stress:
Wolfe's Law
term given for bones growing
Osteogenesis (ossification)
Bones form during:
6th week of pregnancy
Way in which flat bones of the skull and clavicles form (dense CT):
Intramembranous Ossification
Involves formation of hyaline cartilage models:
(All bones except clavicles and skull)
Endochondrial Ossification
(humerus, femur, etc)
Around the diaphysis region of the cartilage model during fetal life
Collar of Bones
Develops in the center of the Diaphysis when osteoblasts and osteoclasts form in shaft of hylaine cartilage model which form:
Primary Ossification Center (POC)
Breakdown the hylaine cartilage and replace it with bone:
Osteoblasts and Osteoclasts of POC
Forms the Shaft of bones (diaphysis)
POC
Forms the Epiphyses:
Secondary Ossification Center (SOC)
Replaces hylaine cartilage of epiphysis with bone:
Osteoclast and Osteoblasts of SOC
All parts of the epiphysis turn to bone except 2 locations:
Articular Cartilage
Epiphyseal Plate (EP)
Cartilage that caps the ends of long bones at joints:
Articular Cartilage
Bone elongation is made possible by:
Epiphyseal Plates
Plate of hyaline cartilage between each epiphysis and daiphysis and is involved with elongation of bones:
Epiphyseal Plates
2 major zones of Epiphyseal Plates:
Zone of Cartilage Formation (ZCF)
(Epiphyseal side)
Zone of Ossification (Diaphysis Side)
Zone where new hyaline cartilage is formed:
Zone of Cartilage Formation
Zone where hyaline cartilage is being converted to bone at the same rate new cartilage forms:
Zone of Ossification
Elongation stops when:
Epiphyseal Plates Close
Inhabit activity of chondroblasts that build new cartilage of EP and result in EP closure
Testo
and
Estrogen
Which has a greater effect Estrogen or Testo in epiphyseal plate closure?
Estrogen
(EP plates close earlier in women)
Causes the rate of ossification of epihyseal plate to exceed new cartilage formation result:
Epiphyseal Plate Closure
Calcium Ions are Essential to:
Skeletal Muscle Contractions
proper beating of heart
Exocytosis
too little calcium in body:
Diaphram doesn't contract properly
Breathing Difficulty
too much calcium in body:
irregular heart beat
Produced by thyroid gland and lowers calcium levels when they rise too high and promote bone growth:
Increase osteoblasts
inhibit osteoclasts
Calcitonin (CT)
(not important)
Raises calcium levels when they drop in blood plasma when calcium falls too low:
(between meals)
Increase osteoclasts
inhibit osteoblasts
Parathyroid hormone (PTH)
2 Vitamin D Deficiencies
Rickets
Osteomalacia
Decreases density of bony matrix
Vit D Deficience
Decreases density of bony matrix in kid (bowed legs) bones become soft:
Rickets
Essential for formation of collagen fibers:
Vitamin C
Vitamin C Deficiency is called:
Scurvy
effects strength of all connective tissue
Source of Growth Hormone;
Pituitary Gland
Pituitary Gland is located:
Sella Turcica of the Sphenoid bone
Excess of growth hormone that occurs in the adult causes bones to thicken
(such as cranial vault and crushes the brain)
Acromegaly
Bacterial infection of bone marrow
Osteomyelitis
OSteomyelitis is caused by:
Staph
Natural part of aging net loss of bones and bones become lighter and more brittle. More common on females
Osteoporosis
Prevention of osteoporosis
Exercise
Don't Smoke
Estrogen HRT