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86 Cards in this Set
- Front
- Back
Certain bones serve as the site of blood cell formation known as:
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Hemopoiesis
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Hemopoiesis occurs in:
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red marrow of certain bones
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Name given to red marrow in flat bones:
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Dipole
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Yellow marrow of bone contains:
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Adipose Tissue
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Forms outer walls of bones
Consists of osteons solid and strong deposited over spongy bone |
Compact Bone
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Found at ends ends of long bones and in the middle portion of most other bones
Consists of trabeculae open spaces between trabeculae |
Spongy Bone
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Interconnected Bars of bone:
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Trabeculae
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4 Classifications of Bone
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Long
Short Flat Irregular |
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Posses long axis with expanded ends
diaphysis(shaft) epiphysis (expanded ends) - contains spongy bone inside |
Long Bone
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cube shaped
compact bone over spongy bone wrist and ankle |
Short Bone
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Bones that form inside a tendon
(patella) |
Sesamoid
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relatively flat bone and may have curved surfaces,
compact bone over spongy bone the spongy bone contains hematopoietic tissue |
Flat
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Unusual shapes that don't fit other categories
(vertebrae,sphenoid) |
Irregular
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Membranes of Bone 2
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Periosteum
Endosteum |
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Dense irregular CT that covers outside of bone except at articular surfaces:
(very vascularized) |
Periosteum
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tufts of collagen fibers that anchor periosteum to underlying compact bone:
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Sharpey's fibers
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Bottom layer of periosteum that rests on top of the bone:
(also found in endosteum) |
Osteogenic Layer of Periosteum
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Oteogenic layer of periosteum contains 2 cells:
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Osteoblasts and Osteoclasts
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Covers the internal surfaces of bones:
(including trebeculae of spongy bone) (areolar ct) |
Endosteum
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Shaft of long bone is called:
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Diaphysis
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Diaphysis is hollow and filled with:
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adipose tissue (yellow marrow)
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Top and bottom of long bone:
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Epihysis
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Epiphysis is filled with:
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Spongy bone
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You can find what cells in Epiphysis:
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Hemopoetic Cells
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Hemopoetic Cells are located:
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Between Trabeculae
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Loomen of diathesis is called:
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Medullary Cavity
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Compact bone is made of structural unit called:
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Osteon
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Canal through the middle of the osteon:
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Central Canal
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Concentric rings of osteons:
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Lamela
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Within the lamela there are cavities called:
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Lacuna
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Within the lacuna there are:
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Osteocytes
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Between the lacuna is the:
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Bony Matrix (filled with calcium salts)
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Tiny canals that connect the central canal to the osteocytes in the lacuna
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Canaliculi
(Filled with interstitial fluid) |
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Compact bone is pierced by ____________ that go from the outside of bones to the inside to provide vascular supply and pass through the central canal of the ostenons
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Perforating Canals
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Bone forming cells:
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Osteoblasts
(bone deposition) |
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Osteoblasts are found:
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In osteogenic layer of
periostium and endostium |
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Osteoblasts make:
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Osteoid
(Bony matrix) |
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How do calcium salts get into osteoids?
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Calcium slats diffuse through capillary walls into the osteoid
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Osteoblasts make:
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osteons and trabeculi in spongy bone
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Osteoblast traped in lacuna:
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osteocyte
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Maintain the health of the bony matrix:
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Osteocytes
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The breaking down of bone:
(bone resorption) |
Osteoclasts
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Osteoclasts are found:
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In the osteogenic layer
(bottom portion of perioseum and endosteum on surface of bone) |
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Osteoclasts secrete an enzyme that breaks down collagen in the bony matrix:
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collagenase
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How does osteoclast work:
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Secrete an acid that brings Ca salts into a solution which then wash out of bones
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When bone shapes itself as it grows and when new bone is created during repair process:
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Bone Remodeling
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Bone Remodeling Includes:
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Osteoblastic Deposition
Osteoclastic Resorption |
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Law that states bone will increase or decrease its strength in response to stress:
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Wolfe's Law
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term given for bones growing
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Osteogenesis (ossification)
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Bones form during:
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6th week of pregnancy
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Way in which flat bones of the skull and clavicles form (dense CT):
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Intramembranous Ossification
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Involves formation of hyaline cartilage models:
(All bones except clavicles and skull) |
Endochondrial Ossification
(humerus, femur, etc) |
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Around the diaphysis region of the cartilage model during fetal life
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Collar of Bones
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Develops in the center of the Diaphysis when osteoblasts and osteoclasts form in shaft of hylaine cartilage model which form:
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Primary Ossification Center (POC)
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Breakdown the hylaine cartilage and replace it with bone:
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Osteoblasts and Osteoclasts of POC
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Forms the Shaft of bones (diaphysis)
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POC
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Forms the Epiphyses:
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Secondary Ossification Center (SOC)
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Replaces hylaine cartilage of epiphysis with bone:
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Osteoclast and Osteoblasts of SOC
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All parts of the epiphysis turn to bone except 2 locations:
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Articular Cartilage
Epiphyseal Plate (EP) |
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Cartilage that caps the ends of long bones at joints:
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Articular Cartilage
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Bone elongation is made possible by:
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Epiphyseal Plates
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Plate of hyaline cartilage between each epiphysis and daiphysis and is involved with elongation of bones:
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Epiphyseal Plates
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2 major zones of Epiphyseal Plates:
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Zone of Cartilage Formation (ZCF)
(Epiphyseal side) Zone of Ossification (Diaphysis Side) |
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Zone where new hyaline cartilage is formed:
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Zone of Cartilage Formation
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Zone where hyaline cartilage is being converted to bone at the same rate new cartilage forms:
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Zone of Ossification
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Elongation stops when:
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Epiphyseal Plates Close
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Inhabit activity of chondroblasts that build new cartilage of EP and result in EP closure
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Testo
and Estrogen |
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Which has a greater effect Estrogen or Testo in epiphyseal plate closure?
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Estrogen
(EP plates close earlier in women) |
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Causes the rate of ossification of epihyseal plate to exceed new cartilage formation result:
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Epiphyseal Plate Closure
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Calcium Ions are Essential to:
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Skeletal Muscle Contractions
proper beating of heart Exocytosis |
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too little calcium in body:
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Diaphram doesn't contract properly
Breathing Difficulty |
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too much calcium in body:
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irregular heart beat
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Produced by thyroid gland and lowers calcium levels when they rise too high and promote bone growth:
Increase osteoblasts inhibit osteoclasts |
Calcitonin (CT)
(not important) |
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Raises calcium levels when they drop in blood plasma when calcium falls too low:
(between meals) Increase osteoclasts inhibit osteoblasts |
Parathyroid hormone (PTH)
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2 Vitamin D Deficiencies
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Rickets
Osteomalacia |
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Decreases density of bony matrix
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Vit D Deficience
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Decreases density of bony matrix in kid (bowed legs) bones become soft:
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Rickets
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Essential for formation of collagen fibers:
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Vitamin C
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Vitamin C Deficiency is called:
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Scurvy
effects strength of all connective tissue |
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Source of Growth Hormone;
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Pituitary Gland
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Pituitary Gland is located:
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Sella Turcica of the Sphenoid bone
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Excess of growth hormone that occurs in the adult causes bones to thicken
(such as cranial vault and crushes the brain) |
Acromegaly
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Bacterial infection of bone marrow
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Osteomyelitis
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OSteomyelitis is caused by:
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Staph
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Natural part of aging net loss of bones and bones become lighter and more brittle. More common on females
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Osteoporosis
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Prevention of osteoporosis
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Exercise
Don't Smoke Estrogen HRT |