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62 Cards in this Set

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cystic fibrosis
genetic disease in which a membrane transport protein is not formed properly, leading to problems with chloride ion transport and damage to tissues as a result of very thick mucus
囊肿性纤维化
nucleic acids
nucleic acids are the information molecules of he cell. they are polymer built up nucleotide monomers, eg deoxyribose nucleic acid and ribose nucleic acid which are the main molecules of inheritance
核酸
where do the information needed to form new cells stored?
in the chromosomes in the nucleus of the cell
形成新细胞的信息被储存在哪里?
DNA - deoxyribonucleic acid
nucleic acid that forms the genetic material of the cell
DNA - 脱氧核糖核酸
RNA - ribonucleic acid
a nucleic acid that is vital for protein synthesis in all living cells and carries the genetic information in many viruses
RNA - 核糖核酸
nucleotide/mononucleotides
monomer of nucleic acid made up of a pentose suger, organic nitrogenous base and a phosphate group.
核苷酸/单核苷酸
pentose suger
monosaccharide that contains five carbon atoms
戊糖
nitrogen-containing base
one of the three parts of nucleotides
氮基
purine
base in nucleic acids with two nitrogen-containing rings
嘌呤
a phosphoric acid
one of the three parts of nucleotides
磷酸
pyrimidines
base in nucleic acids with one nitrogen-containing ring
嘧啶
adenine (A)
a purine base in DNA and RNA
腺嘌呤
guanine (G)
a purine base in DNA and RNA
鸟嘌呤
cytosine (C)
a pyrimidines in DNA and RNA
胞嘧啶
thymine (T)
a pyrimidines base in DNA
胸腺嘧啶
uracil (U)
a pyrimidine base in RNA
尿嘧啶
double helix
molecular structure made famous by DNA that involves two strands twisted together like a spiral staircase
双螺旋结构
complementary base pairs
purine and pyrimidine bases that always pair up in the formation of DNA or RNA
互补碱基对
gene
unit of inheritance
基因
X-ray diffraction
scattering of X-rays by the components of a molecule, used to build up a complex pattern for interpretation of molecule shape
X射线衍射
replicate
to copy
复制
translation
process by which the genetic code is converted into new protein molecules directed by RNA
翻译
ribosome
cell organelle that is the site of protein synthesis
核糖体
triplet code
three bases of DNA which code for a single amino acid
三重码
codon
three base pairs of DNA or RNA coding for a particular amino acid
密码子
complementary strand
the mRNA strand formed alongside the original DNA strand during translation of the genetic code into proteins
互补链
messenger RNA (mRNA)
RNA that carries information from the DNA in the nucleus out into the cytoplasm to be translated into proteins on the ribosomes
信使RNA
antisense strand
the stand of DNA which acts as a template for the formation of mRNA
反义链
transfer RNA (tRNA)
small unit of RNA that codes for a specific amino acid and attaches to it in the cytoplasm before carrying it to the surface of a ribosome for protein synthesis
转移RNA
mutation
change in the genetic code
变异
gamete
sex cell with half the chromosome number of an ordinary cell
配子
thalassaemia
genetic disease in which blood proteins are not manufacturated properly, leading to severe anaemia
地中海贫血
somatic cells
body cell
配子体细胞
point mutation
mutation in one or a small number of nucleotides
基因点突变
chromosomal mutation
mutation involving changes in the position of genes within the chromosome
染色体突变
whole-chromosome mutation
mutation resulting in loss or duplication of whole chromosome
全染色体突变
mutagen
something that causes mutation, eg some chemicals and ionising radiation
诱变剂
meiosis
cell division which results in the production of four daughter cells each with half of the chromosome number of the original cell
减数分裂
Down's syndrome
唐氏综合症
phenotype
the physical and chemical characteristics that make up the appearance of an organism
表型
polypeptide
polymer made of many amino acids
多肽
anaemia
贫血
anabolic reactions
reaction that builds new chemical from more than one reactant
合成代谢反应
catabolic reactions
reaction that breaks down a chemical into more than one product
分解反应
metabolism
combination of anabolic and catabolic reactions that take place in body cells
新陈代谢
metabolic chain/pathway
sequence of metabolic reactions
代谢链/通路
catalyst
a substance that speeds up the rate of a reaction or process
催化剂
specificity
the property of enzymes which means that they only catalyze one particular reaction or type of reaction
特异性
intracellular enzyme
enzyme that works inside a cell
细胞内酶
proteases
蛋白酶
extracellular enzyme
an enzyme that works outside cells, such as digestive enzymes
细胞外酶
substrate
substance that enzyme works on
底物
activation energy
the energy needed to make or break bonds at the beginning of a chemical reaction
活化能量
lock-and-key hypothesis
model of enzyme action based on the idea of an active site which fits specific reactants
锁和钥匙假说
active site
area of enzyme with specific shape which fits the shape of substrate molecules
活动点
induced fit hypothesis
modified version of the lock-and-key hypothesis of enzyme action that proposes a flexible shape for the active site which is modified once the substrate molecule is bound to form an active complex
诱导契合假说
globular protein
protein with tertiary and sometimes quaternary levels of 3D organisation, holding them into globular shapes
球状蛋白质
molecular activity
the number of substrate molecules transformed per minute by a single enzyme molecule
分子活性
turnover number
the number of substrate molecules transformed per minute by a single enzyme
周转次数
saturated
when all of the active sites on an enzyme are taken up
饱和
temperature coefficient, Q10
the effect of temperature on the ratio of a reaction
温度系数,辅酶Q10
thermophilic
heat-loving
嗜热